Thursday, March 18, 2021

Zebrafish: CalTech Hindsight 2020 - Thanks for your great "Jan Huisken, Morgridge Institute for Research" presentation yesterday - "Hindsight 2020 - The Allen Institute Developmental Recording Virtual Series" * In what ways could one send this data through to a single realistic virtual earth for species https://twitter.com/TheOpenBand/status/1367587550274015232?s=19 (think Google Street View with time slider at cell and molecular levels too)? How best to build this for light sheet microscopy as well?" * "A computer-guided design tool to increase the efficiency of cellular conversions" Sascha Jung, Evan Appleton, Muhammad Ali, George M. Church & Antonio del Sol Nature Communications volume 12, Article number: 1659 (2021)


Jo, Jan, (George), CalTech Hindsight 2020 friends, All, 

Thanks for your great "Jan Huisken, Morgridge Institute for Research" presentation yesterday - "Hindsight 2020 - The Allen Institute Developmental Recording Virtual Series"
 https://www.youtube.com/channel/UCrszkCFQtagROYcbqv2lxuQ. Here are my questions from the talk in Zoom - 

"incredible! in what ways could one send this data through to a single realistic virtual earth for species https://twitter.com/TheOpenBand/status/1367587550274015232?s=19 (think Google Street View with time slider at cell and molecular levels too)? How best to build this for light sheet microscopy as well?"

While Light Sheet Microscopy seems with your zebrafish example, and pictures, like it would be very adaptable in creating digital species - eg https://twitter.com/hashtag/RealisticVirtualEarthForSpecies?src=hashtag_click - and at the cellular and potentially molecular levels too, how could this work with a #RealisticVirtualEarthForEvolutionaryBiology - eg https://twitter.com/hashtag/RealisticVirtualEarthForEvolutionaryBiology?src=hashtag_click and a #RealisticVirtualEarthForGenetics too - eg https://twitter.com/hashtag/RealisticVirtualEarthForGenetics?src=hashtag_click in one single realistic virtual earth (think again Google Street View with time slider / Maps / Earth / TensorFlow, with Samsung Neons for realistic avatar bots) ... and even which software is easily group buildable?

And further, how could this be programmed to be coded in what comes after Google Poly (a library of virtual objects), and regarding your digital embryo example, for example, Jan?

And in what ways could a #film-to-3D App - https://twitter.com/hashtag/FilmTo3D?src=hashtag_click - facilitate this, at the STreet View level at first, but later even at the cellular and atomic levels? 

George Church, who gave one of the first talks in this series in 2021 just Tweeted something possibly relevant regarding how genetics and computer design might work -  
Published: 12 March 2021
"A computer-guided design tool to increase the efficiency of cellular conversions" 
Sascha Jung, Evan Appleton, Muhammad Ali, George M. Church & Antonio del Sol
Nature Communications volume 12, Article number: 1659 (2021)

And while your amazing microscope seems relatively stationary, how about a version of Light Sheet Microscopy for the field, and even with a smartphone microscope (have added a few links below from an initial search)? 

How also to begin to model the Axolotl in the very first Open Band Twitter picture and even regarding its genetic engineering with a bird in such software. Could Light Sheet Microscopy even offer research avenues into this ?

https://twitter.com/ReaderMeter/status/1357492535510265857?s=20


https://twitter.com/ReaderMeter/status/1357494302062960643?s=20

eg re also - 
Axolotl https://scientificamerican.com/article/biologys-beloved-amphibian-the-axolotl-is-racing-toward-extinction1 w bird = https://twitter.com/ReaderMeter/status/1357492535510265857?s=19 Could this be a #PokemonGo? #WUaSaugmentedReality  #WUaSgaming #WUaSgeneticEngineeringRevolution ~#RealisticVirtualEarthForSpecies #WUaSgenetics ~ https://scott-macleod.blogspot.com/2021/02/chamaenerion-angustifolium.html ~

https://twitter.com/WUaSPress/status/1367588250236317702?s=20
https://twitter.com/WorldUnivAndSch/status/1367586585672228871?s=20

(And brainstorming-wise, would there even be gaming potential here regarding the Pokemon Go which is based on Google Street View too - eg since the Axolotl looks a little like it could be or become too a Pokemon Go creature)?

Thanks for your superb CalTech presentation on Light Sheet Microscopy and the amazing research you do. Looking forward to staying in communication. Thank you.

All the best, Scott





Hindsight 2020 - The Allen Institute Developmental Recording Virtual Series
 https://www.youtube.com/channel/UCrszkCFQtagROYcbqv2lxuQ


 

for the field ... ?

smartphone microscope

A new smartphone microscope called DIPLE more than doubled its Kickstarter funding goal of about $28,000 well over a month before its December 28 deadline. SmartMicroOptics, the parent company producing the device, said that DIPLE is capable of 1000x magnification while using a smartphone or tablet as a monitor
https://www.popularmechanics.com/technology/gear/a29873640/smartphone-microscope-diple/


pixel smartphone
Smartphone microscope kit promises up to 1,000x magnification
Supercharging the camera in your pocket
By James Vincent  Nov 21, 2019

https://www.theverge.com/circuitbreaker/2019/11/21/20975677/smartphone-microscope-kickstarter-diple-announcement-magnification-zoom
 



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https://upload.wikimedia.org/wikipedia/commons/6/60/Development_of_the_retina.tif





https://en.wikipedia.org/wiki/Zebrafish

https://simple.wikipedia.org/wiki/Zebrafish

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