Friday, October 8, 2021

Bowhead whale (Balaena mysticetus): Aging reversal? ... "The bridge between molecular and cellular worlds is being built. It’s a whole new world …" Ewan Birney * * * Derek & The Dominos live October '70, Allman Bros '73 Cow Palace SF, Grateful Dead, with & 4 great rock concerts


Derek & The Dominos live October '70, Allman Bros '73 Cow Palace SF, Grateful Dead, with  & 4 great rock concerts


Derek & The Dominos October '70
https://youtu.be/Y15yBIE_sDI
The #AllmanBros Band Featuring #JerryGarcia ‎– Live Cow Palace '73
https://youtu.be/DNAmXz8kc6I
#DuaneAllman & #EricClapton '70 - Studio Jams 1 thu 6
https://youtu.be/9u_HmIg6V4M
#GratefulDead '72
https://youtu.be/6F6cMDnzrGQ in #wuAsVR ?








--


-- 
- Scott GK MacLeod  
Founder, President, CEO & Professor
World Univ & Sch (WUaS) - PO Box 442, Canyon, CA 94516 
1) non-profit World University and School - http://worlduniversityandschool.org  
2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 

World Univ & Sch Innovation Research -  scottmacleod.com 

- CC World University and School - like CC Wikipedia with best STEM-centric CC OpenCourseWare - incorporated as a nonprofit university and school in California, and is a U.S. 501 (c) (3) tax-exempt educational organization. 




*

Aging reversal ... "The bridge between molecular and cellular worlds is being built. It’s a whole new world …" Ewan Birney 


Ma, Sandy, All,



Interesting that the head of the NIH stepped down the other day. Here's Stanford Law & 'ethical, legal, and social implications of new biomedical technologies' Prof Hank Greely -

"Can't say I've always agreed w/what he {Francis Collins} has done but, on balance, I think he has been a very positive influence at NIH. I hope he is able to enjoy a long and healthy retirement. (And work on his guitar playing!)"

In what ways could this lead to the large central National Institute of Health (NIH) agency focusing on aging reversal with a new head?

What do you think?

And what do you think Greely is referring to -
" “I don’t think people are going to do that,” says Stanford University bioethicist Hank Greely ..." - https://law.stanford.edu/press/george-church-wants-to-make-matchmaking-a-reality/ ? ... And  (and https://twitter.com/HankGreelyLSJU/status/994204874400202752) ?

Thoughts questions ideas suggestions?

Warmly, Scott


PS 
Here's an article on Covid-19 and aging reversal research -

COVID-19 the new disease of growing old, hastening the work of anti-aging scientists: 
The scientists are searching for drugs and diet supplements that could tweak human biology to better withstand the ravages of time

https://nationalpost.com/health/cutting-edge-science-seeking-treatment-for-aging-itself-is-one-good-thing-to-come-out-of-deadly-pandemic


* 

Timothy Lenderking

2:02 AM (9 hours ago)

to me

Thanks.  I don’t give much thought to aging reversal and I am curious about your interest in it.  To what end?  Yes, I do love life and fully intend to live to 100, but aging reversal seems a bridge too far and not sure it’s worth pursuing.   What am I missing?? 

Sent from my iPhone

On Oct 8, 2021, at 6:53 AM, Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote:



* 

Re: Aging Reversal

Tym, thanks!

If there's some possibility that we could reverse aging per Harvard & MIT Professor of Genetics' George Church in this 60 Minutes' minute-long video  - 

https://youtu.be/bnCEIPQFNnk (by adding genes back in) - via genetic engineering and also live for 100s of years + (even in 30 year olds' bodyminds), the world would be a very very different place.

(Calorie restriction with good nutrition has been the only proven way to extend life an incredible ~10-15 %, across species up to this point - https://sitn.hms.harvard.edu/flash/2020/can-calorie-restriction-extend-your-lifespan/ - which I think I learned about at Reed, but was interested to read this Harvard article published last August 2020, in the midst of the Covid-19 pandemic). 

It's a radical re-envisioning of life in the middle of the genetic engineering revolution, that might work, especially with the advances in vaccine production of the past 18 months. Looking forward to talking with you at 150 years of age+ if it does! 

Could this be further facilitated with new IT tools in a realistic virtual earth for genetics -

  https://twitter.com/TheOpenBand/status/1383620317059244037 - at Work World University and School even, and at the molecular and the cellular levels too (think Google Street View with Time Slider). Was glad to find these recent Tweets from geneticist Ewan Birney + at Cambridge University - 

"The bridge between molecular and cellular worlds is being built. It’s a whole new world …

https://twitter.com/ewanbirney/status/1446213948437639169


Further thoughts questions ideas suggestions?


Scott

Online Chemistry @WorldUnivAndSch in a #RealisticVirtualEarthForChemistry in ONE iterating #RealisticVirtualEarth for EVERYTHING (Think #GoogleStreetView with #TimeSlider, Maps, Earth, #TensorFlowAI at molecular & atomic levels esp.)

https://wiki.worlduniversityandschool.org/wiki/Molecular,_Cellular_and_Developmental_Biology

 /Chemistry @MITOCW ~

https://twitter.com/WorldUnivAndSch/status/1446166692741062666

Same -

https://twitter.com/scottmacleod/status/1446171276624601089


http://scott-macleod.blogspot.com/search/label/longevity




* 

Re: Aging Reversal

Claus, Susan

6:33 AM (5 hours ago)

to me

Since life expectancy has declined for a broad swath of the US population due to regular 'ol health concerns, let's hope all the federal agencies that have a hand in public health work towards universal health care before we worry about extending life expectancy for the part of the population that can afford to live to 90+.

Susan Claus

Librarian, Manager

Children & Teen Services

Northland Public Library

300 Cumberland Road, Pittsburgh PA 15237

412-366-8100 ext. 120  northlandlibrary.org


Northland Library's

Children & Teen Services Department

enables, encourages, empowers, and equips children & teens to become lifelong learners.



From: Scott MacLeod <sgkmacleod@gmail.com>

Sent: Friday, October 8, 2021 12:51 AM

To: Jane MacLeod - V <jkbmacleod@icloud.com>; Sandy MacLeod <sandysculpture@hotmail.com>; Ann Brown <anniebrownbrown@excite.com>; Alden F Briscoe <ABriscoe@brakeleybriscoe.com>; Cathy & Steve Muller <catherinemuller57@gmail.com>; Ed Smyth MD <edlectic@gmail.com>; Kate Williams <klhwilliams@aol.com>; Mark MacLeod <mark_k_macleod@yahoo.com>; Scott MacLeod <sgkmacleod@worlduniversityandschool.org>; Brad & Arlene MacLeod <macleod@usm.maine.edu>; John & Gretchen Kidder <jkidder@vtc.edu>; Joan Kidder <kidderjoan@gmail.com>; Barbara Salisbury <barbsalisbury@gmail.com>; David Byrne <david.stewart.byrne@gmail.com>; Henry Cutter <vfhc@nyc.rr.com>; Claus, Susan <clauss@einetwork.net>; Patti Cobb <pkcobb@pacbell.net>; Claudia Kim Viehland <ckvparsec@comcast.net>; Katie Craig <katie.craig11@gmail.com>; David Newitt <dnewitt@sbcglobal.net>; Greg Highlands <dreadlockcowboy@cheqnet.net>; Pin - Siddartha Mazumdar <sid.mazumdar@gmail.com>; Tym Lenderking <Lenderkingta@yahoo.com>; Charles Field <charles.field@gmail.com>; Nancy Gormley Bevilaqua <nancysdp@gmail.com>; George Riely Dobbin <riely921@yahoo.com>; Hugh M. Thomas <h.thomas@miami.edu>; Jim Spohrer <spohrer@gmail.com>; Ken & Andrea Thompson MD <visiblehands@mac.com>; Viehland, Larry <viehland@chatham.edu>; Matt Lovell <mlovell44@gmail.com>; Peggy Lovell Lynch <plovelllynch@gmail.com>; Peter Norvig <pnorvig@google.com>; Larry & Karen Michalak <otis@berkeley.edu>; Nancy Larson O'Sullivan <n.osullivan@cox.net>; Richard Robb <rrobbmd@verizon.net>; Taylor Andrew Warren <taylorandrewwarren@gmail.com>; Alex Welsh <alexwelsh555@gmail.com>; Jen Warr <jcwarr@hotmail.com>; david.warr@bristolcc.edu <david.warr@bristolcc.edu>; Robin Wilder Younger <robinwyounger@gmail.com>

Subject: Re: Aging Reversal



* 

Scott MacLeod <sgkmacleod@gmail.com>

8:39 AM (2 hours ago)

to Susan


Susan! 


This would be great. And, brainstorming, Work World University and School seeks to code, brainstorming-wise, for all 7.8 billion people on planet for Avatar Bot Electronic Medical Records, each a Wikidata Pin #, ... and even planning for the precision of tele-robotic surgery - http://scott-macleod.blogspot.com/2020/01/greta-oto-avatar-bot-electronic-medical.html?m=0 - with a definition, AND links to the beginning WUaS Medical Schools with Teaching Hospitals. WUaS would seek to facilitate further a kind of actual-virtual, physical-digital universal healthcare. Meanwhile, am appreciative of Obamacare health insurance; and what you think and write makes sense re aging reversal genetic drug therapies' emergence! I don't see either issue in the internet News I read, and haven't heard about these issues re selecting the next NIH head. It looks however like Francis Collins's laboratory at the NIH will continue under his direction after he retires as head, and that it is conducting aging research -


"His lab also seeks to develop new genetic therapies for the most dramatic form of premature aging, Hutchinson-Gilford Progeria Syndrome." 

https://www.nih.gov/news-events/news-releases/francis-collins-step-down-director-national-institutes-health.


Wil UBI Experiments with Stanford Mine Pi to all 7.8 billion people, each a Wikidata Pin # too, on the planet, to distribute also a single cryptocurrency backed by most of ~200 countries' central banks (with Nation States and mutual funds and others investing in Stanford Mine Pi on the Silicon Valley long-term stock exchange even via the WUaS Corporation play a role in planning financially for everyone who might live beyond 90, and even beyond 150+? Will this replace the US dollar, a de facto international currency, and the Euro in 19 of 28 countries in the EuroZone? Nation States' backed cryptocurrency questions will play huge roles in support of this who live beyond 90 and even 150! 

And how will 1 realistic virtual earth help as aging reversal genetic drug therapies emerge, and Avatar Bot Electronic Medical Records, and financing aging? The time slider aspects of Google Street View will aid with machine learning and artificial intelligence. 

Lots of opportunities for developments in health care, research and access!

Cheers, Scott


See upcoming blog post today, and with email to Tym too in the longevity blog label (different from aging reversal!) 


http://scott-macleod.blogspot.com/search/label/longevity




-- 

- Scott GK MacLeod  

Founder, President, CEO & Professor

World Univ & Sch (WUaS) - PO Box 442, Canyon, CA 94516 

1) non-profit World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html


(o) 415 480 4577 - sgkmacleod@worlduniversiryandschool.org 

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com



*

Icelandic mussel named Ming (507 years)


Greenland shark (392 years)


Greenland whale (211 years)


Jeanne Calment (122 years)



* 



! @ewanbirney What about bridges BETW molecular (eg genes) & the #Phenotypes of individuals (in #GoogleStreetView w #TimeSlider) & #species, & BETW the cellular world & #StreetView level too, with #MachineLearning in #RealisticVirtualEarthforGenetics in 1 #RealisticVirtualEarth ?


https://twitter.com/WorldUnivAndSch/status/1446542987115171840?s=20



The bridge between molecular and cellular worlds is being built. It’s a whole new world …
https://twitter.com/ewanbirney/status/1446213948437639169?s=20


Conversation in Twitter
https://twitter.com/scottmacleod/status/1446545850541359109




! @avweigel What about bridges BETW molecular (eg genes) & the #Phenotypes of individuals (in #GoogleStreetView w #TimeSlider) & #species, & BETW the cellular world & #StreetView level too, with #MachineLearning in #RealisticVirtualEarthforGenetics in 1 #RealisticVirtualEarth ?



https://twitter.com/WorldUnivAndSch/status/1446543264421593088?s=20



We are proud to share our work on segmenting up to 35 organelles & macromolecular structures in whole cell isotropic FIB-SEM at 4 & 8nm resolution https://biorxiv.org/content/10.1101/2020.11.14.382143v1 1/12
https://twitter.com/avweigel/status/1328688972793585664?s=20



--


-- 
- Scott GK MacLeod  
Founder, President, CEO & Professor
World Univ & Sch (WUaS) - PO Box 442, Canyon, CA 94516 
1) non-profit World University and School - http://worlduniversityandschool.org  
2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 

World Univ & Sch Innovation Research -  scottmacleod.com 

- CC World University and School - like CC Wikipedia with best STEM-centric CC OpenCourseWare - incorporated as a nonprofit university and school in California, and is a U.S. 501 (c) (3) tax-exempt educational organization. 




* 

At scale #Genomics?

At scale #Genomics? w "The bridge betw #molecular & #cellular worlds is being built. It’s a whole new world " @ewanbirney https://www.genome.gov/player/dCTxYJpilwQ/PL1ay9ko4A8sk0o9O-YhseFHzbU2I2HQQp in 1 #RealisticVirtualEarthForGenetics >http://scott-macleod.blogspot.com/2021/10/bowhead-whale-aging-reversal.html w #FilmTo3D App & #TextInTheSidebar of #StreetView for new publishing?




* 

Ma, Sandy, Tym, All, further, 


O my goodness, here's Brit Ewan Birney, and a leading Geneticist saying "The bridge between molecular and cellular worlds is being built. It’s a whole new world …" - https://twitter.com/ewanbirney/status/1446213948437639169  (https://twitter.com/WorldUnivAndSch/status/1446543264421593088?s=20) - and I've been calling for a single realistic virtual earth at the cellular, molecular/atomic, and Street View levels for a long time now ... with whole new worlds of Information Technology tools ahead here too ... and with much potential for aging reversal genetic engineering drug therapies ahead, and longevity too! 

Here's Ewan Birney in an interesting oral history from the National Human Genome Research Institute here - genome.gov/ with him - https://www.genome.gov/player/dCTxYJpilwQ/PL1ay9ko4A8sk0o9O-YhseFHzbU2I2HQQp ...


Talk with you in 150 years, possibly, and 250 years ... and how far ahead???? (Philosophical & scientific skepticism here is much warranted), but see the emails from Susan and you in these regards too! 

This blog post begins with 4 great rock and roll concerts from the '70s ! :)

Warm regards, 
Scott







* 

















https://en.wikipedia.org/wiki/Bowhead_whale

https://commons.wikimedia.org/wiki/Balaena_mysticetus

(longevity, and even re aging reversal ... 

Icelandic mussel named Ming (507 years)

Greenland shark (392 years)

Greenland whale (211 years)

Jeanne Calment (122 years) )

Saturday Essay |How does it feel to live for centuries? Human immortality is closer than ever, but if it materialized, it would produce a couple of problems
Culture
25.9. 2:00

...




at

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