Sunday, September 15, 2024

Mountain goat (Oreamnos americanus): Dear @geochurch @DrCaliff_FDA @amplesa Frontier in #ExtremeLongevity questions: How to live for 123 years & what genes to add for this per https://youtu.be/bnCEIPQFNnk? I'd like to live to ~2085 & for my mother to live to 149 yo (~2111) How w a #RealisticVirtualEarthForLongevity too? * * How to develop an #AgingReversalMachine in a #RealisticVirtualEarth #ForAgingReversal (& #ForExtremeLongevity) w #AlphaFold3Server for #MLprediction of ALL #LifesMolecules #GeneticDrugTherapies & re #GStreetView w #TimeSlider interoperable with #AvatarAgentElectronicHealthRecords? Sunday Plan * How was Dolly the sheep cloned - steps involved (in enzyme activity)?


Dear @geochurch @DrCaliff_FDA @amplesa Frontier in #ExtremeLongevity questions: How to live for 123 years & what genes to add for this per https://youtu.be/bnCEIPQFNnk? I'd like to live to ~2085 & for my mother to live to 149 yo (~2111) How w a #RealisticVirtualEarthForLongevity too?


Dear @geochurch @DrCaliff_FDA @amplesa Frontier in #ExtremeLongevity questions: How to live for 123 years & what genes to add for this per https://youtu.be/bnCEIPQFNnk? I'd like to live to ~2085 & for my mother to live to 149 yo (~2111) How w a #RealisticVirtualEarthForLongevity too?

Pic of my mother in her garden today 9/15/24


Pic of Roaring Plains West Wilderness area, WV, South Prong trail sign on September 14, 2024



Video of George Church 60 Minutes 




AND 


retweeting 



AND

retweeting







* * 

How to develop an #AgingReversalMachine in a #RealisticVirtualEarth #ForAgingReversal (& #ForExtremeLongevity) w #AlphaFold3Server for #MLprediction of ALL #LifesMolecules #GeneticDrugTherapies & re #GStreetView w #TimeSlider interoperable with #AvatarAgentElectronicHealthRecords?  








Retweeting 

Can we reverse aging? 
7 yrs ago, Ocampo et al. showed that partial reprogramming can ameliorate aging hallmarks. But, OSKM induction has safety limitations & no new factors have emerged since. Here, biorxiv.org/content/10.110… we used 🧬 screens to find new rejuvenation factors🧵1/8





1

https://x.com/amplesa/status/1737852952407326906


2

https://x.com/amplesa/status/1737852956572266885


3

https://x.com/amplesa/status/1737852961467039803


4

https://x.com/amplesa/status/1737852964830953802


5

https://x.com/amplesa/status/1737852968597442653


6

https://x.com/amplesa/status/1737852974599418175


7

https://x.com/amplesa/status/1737852982539239770


8

https://x.com/amplesa/status/1737852985332687103


9

https://x.com/LaurieGreen36/status/1738574418605973649


11

https://x.com/amplesa/status/1738625223509893273





* * * 

Sunday Plan 


Hi Ma, (Pin, Ed), 


Thanks for your email and the invitation (and after I got the new, newly secure and private, etc., too? Chase credit card yesterday, post lock up of criminal Chase bank Wilkinsburg 15221 employees, like j.w.??? ... which I perhaps saw signs for as I drove out of town on Friday toward Roaring Plains west Wilderness WV ... I think I'll hike on the Southern Prong trail there next time, which I passed this time, kind of scouting out this new wilderness area adjacent to the Dolly Sods Wilderness Area ... ) 

Looking forward to seeing you then (then) ... Dark Hollow park too would be nice as could be the Todd forest area for a walk. 

Will T, after he called 2 Sundays ago I think, be able to make my and WUaS's move into a newly safe Canyon 94516, and the SF Bay Area, happen in 2024? (Otherwise, he said, if not, we could meet in DC at a musical event in the spring and go out with 2 Iranian women, one of whom is a musician in California whom he recently visited) ...  Received a Yemen missile news' message from Google this morning on my smartphone ... AND re my whistle blowing about the sf quaker meeting in around 2017 ... and re the renter from the AFSC upstairs from the middle east ... and the wrongful buying and selling of people in the illegal sex, drugs and violence etc industries internationally ... and with kids even tragically ... and all the cultures' and identities and countries'  logics in the mix ... and  from a US state department and a Washington DC perspective too  ... and re WUaS growing a worldwide abolition movement ... 

Thanks to George re Desiderata - https://www.desiderata.com/desiderata.html - and re wedgie issues ... and re Lacan and his thinking about desire (post Id -thinking re freud perhaps) ... https://scott-macleod.blogspot.com/search/label/Jacques%20Lacan%20MD ... 

How to de-extinct Dad GKM MD with parallels to the spectacular Dolly the Sheep cloning in Scotland too in 1996, brainstorming-wise ...  ?

Fondly, Scott


How to develop an #AgingReversalMachine in a #RealisticVirtualEarth #ForAgingReversal (& #ForExtremeLongevity) w #AlphaFold3Server for #MLprediction of ALL #LifesMolecules #GeneticDrugTherapies & re #GStreetView w #TimeSlider interoperable with #AvatarAgentElectronicHealthRecords?  








Retweeting 

Can we reverse aging? 
7 yrs ago, Ocampo et al. showed that partial reprogramming can ameliorate aging hallmarks. But, OSKM induction has safety limitations & no new factors have emerged since. Here, biorxiv.org/content/10.110… we used 🧬 screens to find new rejuvenation factors🧵1/8




PPS
Just searched - 

How was Dolly the sheep cloned - steps involved (in enzyme activity)? 


How They Cloned a Sheep

udder cells

1. Scientists took udder cells from Dolly’s DNA mother. They let the cells multiply and then they stopped the process when they had divided enough.

egg cells

2. They took an egg cell from a different sheep and removed the nucleus.

udder cell joins to cell without nucleus using electricity

3. They put one udder cell next to the egg cell without a  nucleus and joined them using electricity. The egg cell now contained all the udder cell’s DNA.

cells grow into an embryo

4. The egg cell divided until it developed into an embryo. An embryo is the early stage of an animal before it has been born or hatched. This embryo was placed inside a third sheep. Five months later, this sheep gave birth to Dolly .





PPPS
And how to do this in a realistic virtual earth for genetics ? 







PPPPS

Somehow derive or extrapolate cells from a digital picture re Dad (and especially from Sandy and me, and our biological cousins on Dad's side)?




--

Society, Information Technology, and the Global University (2024, forthcoming)

- Scott GK MacLeod  
Founder, President, CEO & Professor
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* 



























https://en.wikipedia.org/wiki/Mountain_goat

https://commons.wikimedia.org/wiki/Oreamnos_americanus

...



at

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