Saturday, July 27, 2024

Asian elephant: Hi @EwanBirney @CecLindgren @GeoChurch #GeneCoders, on digital side of #PhysicalDigital #RealisticVirtualEarthFor #BirthAndGestation re #WoolyMammoth #Deextinction https://colossal.com/mammoth/ & https://www.cnn.com/2024/03/09/world/woolly-mammoth-elephant-stem-cells-scn/index.html & humans w #AvatarAgentElectronicRecords, how to code #PostPartumBleeding genes genes? * * * Shared this as feedback to Gate.com, partly based in Bulgaria, I think, and which hosts my and WUaS's websites: Wondering how #MITOCW- centric wiki @WorldUnivAndSch can plan for #AIandML & data sources & with the #WUaSwebsite (& for all 200 countries eg #BulgariaWUaS) * * * Paris Olympics live updates ... To https://wiki.worlduniversityandschool. org/wiki/Athletics,_Physical_Education_and_Recreation ? ... and where @WorldUnivAndSch seeks #OlympicStudents fr 200 #WUaScountries ~

 



Hi @EwanBirney @CecLindgren @GeoChurch #GeneCoders, on digital side of #PhysicalDigital #RealisticVirtualEarthFor #BirthAndGestation re #WoolyMammoth #Deextinction https://colossal.com/mammoth/ & https://www.cnn.com/2024/03/09/world/woolly-mammoth-elephant-stem-cells-scn/index.html & humans w #AvatarAgentElectronicRecords, how to code #PostPartumBleeding genes ?


Hi @EwanBirney @CecLindgren @GeoChurch #GeneCoders, on digital side of #PhysicalDigital #RealisticVirtualEarthFor #BirthAndGestation re #WoolyMammoth #Deextinction https://colossal.com/mammoth/ & https://www.cnn.com/2024/03/09/world/woolly-mammoth-elephant-stem-cells-scn/index.html & humans w #AvatarAgentElectronicRecords, how to code #PostPartumBleeding genes genes?










Retweeting - 

Amazing collaboration  
@FinnGen_FI
 
@ESTbiobank
 
@decodegenetics
 
@uk_biobank
 #DBDScohort #MoBAcohort identified genetics involved in postpartum bleeding- the condition accountable for most maternal deaths globally 🌍





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Scientists inch forward in efforts to resurrect an extinct giant
By Katie Hunt, CNN
 5 minute read
Published 3:30 AM EST, Sat March 9, 2024


the elephant's cells could be used to make eggs and sperm and an embryo that could be implanted into some kind of artificial womb.


https://www.cnn.com/2024/03/09/world/woolly-mammoth-elephant-stem-cells-scn/index.html#:~:text=Engineering%20a%20woolly%20mammoth%20hybrid,some%20kind%20of%20artificial%20womb.



Gestation & Birth
https://colossal.com/mammoth/





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Hi @EwanBirney @CecLindgren #GeneticsCoders re #EvergreenTrees vs #DeciduousTrees - what are #GCell & #GMolecular Mechanisms for conifers' '#ExtremeLongevity' greenness vs broadleaf trees' #LeafDeath (re #LongevityGenetics) & how to code in #RealisticVirtualEarth differentially?

https://x.com/WorldUnivAndSch/status/1817207315164004404

https://x.com/Q_YogaMacFlower/status/1817206833443909905

https://twitter.com/scottmacleod/status/1817207490884345988

All languages ever at WUaS (7164 currently)





Retweeting - 

Amazing collaboration  
@FinnGen_FI
 
@ESTbiobank
 
@decodegenetics
 
@uk_biobank
 #DBDScohort #MoBAcohort identified genetics involved in postpartum bleeding- the condition accountable for most maternal deaths globally 🌍

https://x.com/ceclindgren/status/1817106510998315510




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Thnx #EwanBirney re #EvergreenTrees  vs #DeciduousTrees - what are #GCellular & #GMolecular Mechanisms for conifers' (300M yrs BP) '#ExtremeLongevity' greenness vs #angiosperm (145M yrs BP), broadleaf trees' #LeafDeath & how to code both in #RealisticVirtualEarth differentially?







Retweeting

A reminder ( it’s an evergreen topic) - humans are a genetically undiverse species - we exploded out Africa in a heartbeat of evolutionary time and we predominantly adapted to the multitude of environments by our behaviour, passing that knowledge down culturally in groups 





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slightly different - 

Thnx #EwanBirney re #EvergreenTrees  vs #DeciduousTrees - what are #GCellular & #GMolecular Mechanisms for conifers (300M yrs BP) '#ExtremeLongevity' greenness vs #angiosperm (145M yrs BP), broadleaf trees' #LeafDeath & how to code both in #RealisticVirtualEarth differentially ?




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#Deextinct the #WoolyMammoth virtually too @geochurch? In an emerging #WUaSMultimediaBarn in Canyon94516 ..


#Deextinct #WoolyMammoth virtually too @geochurch in emerging #WUaSMultimediaBarn in #Canyon94516 & think #GStreetView w #TimeSlider #GMaps #GEarth #TensorFlowAI with #AppleVisionPro #DigitalMask -https://www.theage.com.au/technology/finally-a-new-apple-device-really-worth-talking-about-20240204-p5f286.html A #DigitalPhysicalGenome & add to
https://newrepublic.com/article/169528/woolly-mammoth-alaska-colossal-thiel ?

https://twitter.com/WorldUnivAndSch/status/1768669424016302238

https://twitter.com/scottmacleod/status/1768669571223834692






Vision pro pic ?






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#Deextinct the #WoolyMammoth virtually too @geochurch? In an emerging #WUaSMultimediaBarn in Canyon94516 - think Google Street View w Time Slider GMaps, Earth TensorFlowAI - with AppleVisionPro DigitalMask


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Create digitally its DigitalPhysical Genome & add to 



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Andy Lamey

December 15, 2022
COLOSSAL PROBLEM
The De-Extinction of the Woolly Mammoth Is a Legal and Regulatory Nightmare
A biotech firm wants to resurrect the Pleistocene mammal in Alaska—and it’s not clear the U.S. government can stop them.







Church to de-extinct woolly mammoths

Nature Journal
https://www.nature.com › nature biotechnology › news
by L DeFrancesco · Cited by 8 — Harvard Medical School's George Church has launched Colossal, his latest venture, with a mission to bring woolly mammoths back to life.


News
Published: 07 October 2021
CLIMATE EMERGENCY

Church to de-extinct woolly mammoths
Laura DeFrancesco
Nature Biotechnology volume 39, page1171 (2021)Cite this article

4562 Accesses

4 Citations

146 Altmetric

Metrics 

Getting there involves 11 steps, starting with sequencing the woolly mammoth genome and ending with placing live animals on Earth. In between, the team will be identifying the genes that make a woolly mammoth (compared with an elephant, its closest genetic relative), editing those genes into an elephant embryo using CRISPR, and gestating the gene-edited embryo to term. Church’s team, which up until now had been working with very little funding, has identified 60 genes that confer mammoth-like features — some of which, such as those that confer cold tolerance, will be edited in. In another Church start-up, e-Genesis, 42 genes have been edited in pigs to make their organs available for human transplantation — a proof of concept for the approach.



https://www.nature.com/articles/s41587-021-01096-y




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Aging Reversal Machine ? - An #AgingReversalMachine from these 8 Tweets ? 

In 
view: #GStreetViewRoom https://youtu.be/q9FBhEAXRY4 with #timeslider >An #AgingReversalMachine from these 8 Tweets w #FlywireFly @amplesa @geochurch #PeterNorvig & think in #GStreetView w #GCellView #GAtomView in #RealisticVirtualEarthForGenomics #RealisticVirtualEarthForGenetics ?

https://twitter.com/WorldUnivAndSch/status/1775874497704243374







Retweeting -

Can we reverse aging?
7 yrs ago, Ocampo et al. showed that partial reprogramming can ameliorate aging hallmarks. But, OSKM induction has safety limitations & no new factors have emerged since. Here, https://biorxiv.org/content/10.1101/2023.11.13.566787v1 we used 🧬 screens to find new rejuvenation factors🧵1/8

https://twitter.com/amplesa/status/1737852952407326906

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An #AgingReversalMachine from these 8 Tweets w #crisprCas9 - https://twitter.com/amplesa/status/1737852952407326906 @amplesa @geochurch #PeterNorvig & think in #GStreetView w #timeslider #GCellView #GMoleculeView in #RealisticVirtualEarthForGenomics #RealisticVirtualEarthForGenetics
-https://scott-macleod.blogspot.com/2023/12/lily-bl-national-flower-of-saint.html ?

https://twitter.com/scottmacleod/status/1765748331618115837

https://twitter.com/WorldUnivAndSch/status/1765747718721290723

https://twitter.com/TheOpenBand/status/1765749431150764336





Retweeting -

Can we reverse aging?
7 yrs ago, Ocampo et al. showed that partial reprogramming can ameliorate aging hallmarks. But, OSKM induction has safety limitations & no new factors have emerged since. Here, https://biorxiv.org/content/10.1101/2023.11.13.566787v1 we used 🧬 screens to find new rejuvenation factors🧵1/8


https://twitter.com/amplesa/status/1737852952407326906



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#RealisticVirtualEarthForProteins  

Much to learn from creative #deextinction of #WoolyMammoth for #ExtremeLongevityGenetics esp in #RealisticVirtualEarthForSpecies #ForGenomics #ForGenetics (think #GStreetView w #TimeSlider even as #AgingReversalMachine) @WorldUnivAndSch Critiques here too:










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Much to learn from creative #deextinction of #WoolyMammoth for #ExtremeLongevityGenetics esp in #RealisticVirtualEarthForSpecies #ForGenomics #ForGenetics (think #GStreetView w #TimeSlider even as #AgingReversalMachine) @WorldUnivAndSch Critiques here too:












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Shared this as feedback to Gate.com, partly based in Bulgaria, I think, and which hosts my and WUaS's websites: 

Wondering how #MITOCW- centric wiki @WorldUnivAndSch can plan for #AIandML & data sources & with the #WUaSwebsite (& for all 200 countries eg #BulgariaWUaS)  


Wondering how #MITOCW- centric wiki @WorldUnivAndSch can plan for #AIandML & data sources & with the #WUaSwebsite (& for all 200 countries eg #BulgariaWUaS  -  https://wiki.worlduniversityandschool.org/wiki/Bulgaria (from  https://wiki.worlduniversityandschool.org/wiki/Nation_States) for online #freeWUaSdegrees in #BulgarianWUaS #WUaSai #WUaSML ~













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Wondering how MIT OCW- centric wiki World Univ & Sch can plan for AI and ML and data sources and with the WUaS web site and for all 200 countries eg Bulgaria WUaS  -  https://wiki.worlduniversityandschool.org/wiki/Bulgaria ( from  https://wiki.worlduniversityandschool.org/wiki/Nation_States) for free WUaS online degrees in Bulgarian (Wondering how #MITOCW- centric wiki @WorldUnivAndSch can plan for #AIandML & data sources & with the #WUaSwebsite (& for all 200 countries eg #BulgariaWUaS  -  https://wiki.worlduniversityandschool.org/wiki/Bulgaria (from  https://wiki.worlduniversityandschool.org/wiki/Nation_States) for online #freeWUaSdegrees in #BulgarianWUaS #WUaSai #WUaSML ~ https://x.com/sgkmacleod/status/1817268914398621859 )





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Paris Olympics live updates: USA wins 1st medal; Ledecky wins heat in 400 freestyle 7/27/24 https://www.usatoday.com/story/sports/olympics/2024/07/27/paris-olympics-live-updates-results/74190536007/
To https://wiki.worlduniversityandschool. org/wiki/Athletics,_Physical_Education_and_Recreation? where @WorldUnivAndSch seeks #OlympicStudents fr 200 #WUaScountries ~

https://twitter.com/scottmacleod/status/1817214840487710890







--


Society, Information Technology, and the Global University (2024, forthcoming)

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- PO Box 442, Canyon, CA 94516 
- 5816 Callowhill St., Pittsburgh, PA 15206

1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 
 World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com 








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https://en.wikipedia.org/wiki/Asian_elephant

https://commons.wikimedia.org/wiki/Category:Elephas_maximus


https://commons.wikimedia.org/wiki/Elephas_maximus

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