Recording of 'M 7/28/25 #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #KaiserPermanenteWUaS #Germline' https://t.co/jtYd6EnsOr
— WorldUnivandSch (@WorldUnivAndSch) July 28, 2025
- https://t.co/W0hRDs6P1r -https://t.co/KBSXBYXIs4
-https://t.co/98DB8664IK #RealisticVirtualEarth #ForAgingReversal #ForGermlineEditing?
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/Q_YogaMacFlower/
Vid pic
Recording of 'M 7/28/25 #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #KaiserPermanenteWUaS #Germline' https://t.co/F150Mj3bIZ - https://t.co/jHyKx14fru -https://t.co/3Q17XvwzAj -https://t.co/vIVpBwW34d #RealisticVirtualEarth #ForAgingReversal #ForGermlineEditing?
— WUaSPress (@WUaSPress) July 28, 2025
https://www.linkedin.com/
https://www.linkedin.com/
*. *
Dear Universitians, friends, Stuart McNish, Jamie Dimon, Larry Tessler, all,
Topic: M 07/28/25 open MIT OCW-centric wiki World Univ & Sch WUaS News and Q&A, with Zoom URL
Time: Jul 28, 2025 10:00 AM Pacific Time (US and Canada)
Join Zoom Meeting
https://us04web.zoom.us/j/
Meeting ID: 784 9942 6767
Passcode: r6mQu5
Scott GK MacLeod
Recording will be posted here -
https://www.youtube.com/@
https://x.com/WorldUnivAndSch/
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://www.linkedin.com/
https://www.linkedin.com/
https://youtu.be/So-Sf_REm88
https://
-https://scott-macleod.
-https://www.youtube.com/@
https://scott-macleod.
Indian hare: Oxford University ...
MacLeod, Scott GK. 2025. Germline editing re creating a
The Science and Ethics of Editing Humans
by Henry T. Greely
2022.
Wyethia angustifolia (narrow leaf mule ear): How likely are some of us with good health care coverage to live beyond 122 years of age & as #AgingReversal and #ExtremeLongevity genetic drug therapies emerge FDA-approved? And how could a realistic virtual earth help? #GeminiAIreAging - "A virtual Earth, analogous to Google Street View but extending to cellular and molecular levels with a time slider, could revolutionize personalized medicine for extreme longevity. This "digital twin" of an individual ... " * * * germline editing how best to create a #
...
https://scott-macleod.
Checkerbloom (Sidalcea malviflora): INCREDIBLE: #GeminiAIreAging ~ "A #virtualEarth, analogous to #GStreetView but extending to cellular & molecular levels w a time slider, could #
https://scott-macleod.
How could germline editing affect aging reversal genetics in humans?
- Germline editing could introduce genetic changes that slow down the aging process and increase lifespan, with these changes being passed down to offspring.
- It could potentially eliminate or reduce the risk of age-related diseases like Alzheimer's, heart disease, and cancer, not just in the treated individual but also in their descendants.
- By targeting genes that influence cellular repair and regeneration, germline editing could lead to a longer period of healthy living, free from age-related decline.
- It may be possible to enhance the regenerative capacity of stem cells, allowing for better tissue repair and organ function throughout life.
- Modifying the human germline carries the risk of introducing unintended and potentially harmful genetic changes that could affect future generations.
- Germline editing technologies are likely to be expensive and may not be accessible to everyone, potentially exacerbating existing health inequalities.
- Some fear that germline editing could lead to the enhancement of traits beyond disease prevention, raising concerns about genetic discrimination and social justice.
- Altering the human germline could have unpredictable consequences for human evolution, potentially affecting the natural selection process.
- It is impossible to obtain informed consent from future generations who would inherit the edited genes.
- The widespread use of germline editing could have profound societal impacts, including changes in population demographics and social structures.
Abstract
Rapid advancements have taken place in gene therapy technology. However, effective methods for treating aging- or age-related chronic diseases, which are often closely related to genes or even multiple genes, are still lacking. The path to developing cures is winding, while gene therapy that targets genes related to aging represents an exciting research direction with tremendous potential. Among aging-related genes, some candidates have been studied at different levels, from cell to organismal levels (e.g., mammalian models) with different methods, from overexpression to gene editing. The TERT and APOE have even entered the stage of clinical trials. Even those displaying only a preliminary association with diseases have potential applications. This article discusses the foundations and recent breakthroughs in the field of gene therapy, providing a summary of current mainstream strategies and gene therapy products with clinical and preclinical applications. Finally, we review representative target genes and their potential for treating aging or age-related diseases.
Keywords: gene therapy, aging, aging-related disease, gene replacement, CRISPR
#AgingReversalResearch #UCBerkeley? - in a #RealisticVirtualEarthWUaS #ForBloodPlasma?
How to do this in a #RealisticVirtualEarthWUaS #ForBloodPlasma? In 2005, Cal researchers made surprising discovery that making conjoined twins out of young & old mice can rejuvenate tissues & reverse signs of aging:
https://vcresearch.berkeley.
https://x.com/WorldUnivAndSch/
https://x.com/scottmacleod/
https://x.com/Q_YogaMacFlower/
[https://youtu.be/1j4vPux-Byc
Let’s talk about CRISPR People (w/ Henry T. Greely, Stanford Center for Law and the Biosciences)]. Vancouver, British Columbia, Canada: Conversations That Matter.
... as a reference to the 'Aging Reversal Genetics' and 'Genetics' wiki Subjects/ (open wiki) Schools at MIT OCW-centric wiki World Univ & Sch -
https://wiki.
https://wiki.
More later, Friendly NtF NtQ Quaker regards, all the best, Scott
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
AND
https://www.linkedin.com/
PPS
Are you on TwitterX presently? And are you related to AFSC's former General Secretary Mary Ellen McNish, by any chance? Friendly regards, Scott (GK Macleod - https://www.youtube.com/@
Hi Scott,
I am not directly related to Mary Ellen McNish.
And yes I am on X
Checkerbloom (Sidalcea malviflora): {INCREDIBLE: #GeminiAIreAging} . . . * * * Great! - @SenAlexPadilla "SF-Based #InternetArchive Is Now a #FederalDepositoryLibrary. What Does That Mean?" https://www.kqed.org/news/
https://scott-macleod.
What does intelligent mean in 'real time intelligence systems' ? Gemini AI response -
Fascinating: What does intelligent mean in #RealTimeIntelligenceSystem
https://g.co/gemini/share/
In real-time intelligence systems, "intelligent" refers to ability of system to perceive, process, reason, learn:
https://www.toolify.ai/ai-
real-time intelligence systems & for education and learning in a realistic virtual earth
- Virtual field trips and explorations: Utilizing VR/AR, students can explore historical sites, geographical locations, or even delve into complex scientific processes within a highly realistic virtual earth environment.
- AI-powered simulations: AI can create and adapt simulations mirroring real-world scenarios, allowing students to experiment, practice skills, and apply theoretical concepts in a safe and engaging setting, according to OpenExO.
- Personalized learning paths: AI algorithms analyze student data (performance, preferences, pace) in real-time, tailoring educational content and difficulty levels to individual needs, says Microsoft.
- Real-time feedback and adaptation: AI provides immediate feedback and suggests adjustments based on student interactions within the virtual environment, helping them correct mistakes and reinforce understanding.
- Proactive academic support: AI can identify early indicators of academic challenges and recommend additional resources or exercises in real-time.
- AI-driven virtual learning platforms: AI can enable the creation and management of virtual learning environments, including virtual classrooms, labs, and interactive 3D learning platforms, fostering collaborative learning and engagement.
- Context-aware responses: AI systems can adjust content and delivery methods based on the learner's situation, progress, and needs.
- Integration with existing technologies: AI-driven virtual environments can integrate with Learning Management Systems (LMS) and other existing educational technologies to provide a more holistic and effective learning experience.
- Cost and accessibility: Implementing advanced AI and VR/AR solutions can be expensive, hindering widespread adoption, especially in underfunded regions.
- Technical expertise and infrastructure: Developing and managing these systems require specialized technical expertise and robust network infrastructure.
- Data privacy and security: Protecting student data collected by AI systems is crucial, requiring robust data protection policies and adherence to privacy regulations.
- Algorithmic bias: AI algorithms may inadvertently reinforce existing biases if trained on biased data, requiring careful design and ongoing evaluation of these systems.
- Balancing virtual and real-world skills: Over-reliance on virtual learning may potentially limit the development of essential in-person social and practical skills.
- Virtual Field Trips (VFTs): Imagine taking a Virtual Field Trip to explore geological formations, analyze landforms, and investigate natural hazards – all within a dynamic and realistic virtual earth environment.
- Real-time environmental monitoring: Integrating live satellite imagery from platforms like NOAA's interactive map or NASA Earthdata into virtual earth environments can allow students to monitor environmental changes, track storms, and analyze climate patterns in real-time.
- Urban planning and land use studies: Google Earth Engine's extensive catalog of satellite imagery and geospatial datasets, when combined with real-time intelligence systems, could enable students to explore urban development, analyze land use changes, and plan sustainable cities within a realistic virtual earth context.
- Interactive simulations for complex concepts: Virtual reality can visualize abstract concepts in three-dimensional space, helping students grasp complex topics in subjects like mathematics, physics, and chemistry through interactive simulations within virtual environments.
- Personalized learning paths and adaptive assessments: AI-powered learning platforms and adaptive assessments can leverage real-time data from student interactions within virtual environments to tailor learning paths, adjust the difficulty of exercises, and provide personalized feedback, as seen in platforms like Carnegie Learning and Smart Sparrow.
- MIT OCW, known for its extensive collection of free online course materials, could incorporate interactive simulations and virtual environments into courses such as "Earth, Atmospheric, and Planetary Sciences".
- The use of tools like GeoWeaver, an open-source workflow management system, could help integrate Python code and Shell scripts within virtual earth environments, allowing researchers and students to leverage computing resources and create shareable workflows for Earth science studies.
- Implementing AI-powered virtual learning solutions can be expensive due to the cost of hardware, software, and training for staff.
- Protecting student data privacy and ensuring responsible use of generative AI tools within educational environments is crucial.
- Educators may require adequate training and support to effectively utilize these new technologies in their classrooms.
a #MITOCW-centric wiki @WorldUnivAndSch #WUaSabolition movement is growing -
https://x.com/Q_YogaMacFlower/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
Retweeting -
Fascinating: What does intelligent mean in #RealTimeIntelligenceSystem
https://g.co/gemini/share/
In real-time intelligence systems, "intelligent" refers to ability of system to perceive, process, reason, learn:
https://www.toolify.ai/ai-
https://x.com/WorldUnivAndSch/
https://twitter.com/
https://twitter.com/
An #AIandML #ITplatform w
https://sites.google.com/
AND w
#BangladeshWUaS - https://sites.google.com/
from
http://
https://scott-macleod.
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/TheOpenBand/
Regarding
How to do this in a #RealisticVirtualEarthWUaS #ForBloodPlasma? In 2005, Cal researchers made surprising discovery that making conjoined twins out of young & old mice can rejuvenate tissues & reverse signs of aging:
https://vcresearch.berkeley.
https://x.com/WorldUnivAndSch/
https://x.com/scottmacleod/
https://x.com/Q_YogaMacFlower/
-https://
-https://scott-macleod.
HERE:
2548 Bancroft Way Berkeley:
https://www.google.com/maps/@
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/sgkmacleod/
Sunday, July 27, 2025
Lotus (Kamala/Padma): Bhagavad Gita, and some implications re Yoga too -
Bhagavad Gita, and some implications re Yoga too -
What implications for today's knowledge generation, in a scientific world with information technology, are in the Bhagavad Gita, & what is Jnana Yoga regarding Yoga & re the pursuit of knowledge in the context of this Gita battle, and also India at the time the Bhagavad Gita was written (~400 BCE) ?
GREAT response from
Gemini AI -
For today's knowledge generation in a scientific world with information technology, Jnana Yoga offers profound implications:
* Discernment in the Age of Information Overload: Just as ancient seekers had to discern truth from illusion, modern individuals navigate vast amounts of information. Jnana Yoga's emphasis on distinguishing between the real and unreal, permanent and temporary, helps in critically evaluating data and identifying genuine knowledge amidst misinformation.
* Self-awareness in Technological Advancement: With increasingly immersive technologies, understanding one's true self and purpose can be challenging. Jnana Yoga promotes introspection and self-inquiry, which can lead to greater self-awareness and prevent individuals from becoming solely defined by their digital identities or technological tools.
* Ethical Framework for AI and Data: The pursuit of knowledge in Jnana Yoga is rooted in dharma (righteousness). In a scientific world rapidly advancing in AI and data, this ethical framework becomes crucial for guiding the development and application of technology responsibly, ensuring it serves humanity's highest good rather than being driven solely by utility or profit.
* Holistic Understanding: While science focuses on empirical knowledge, Jnana Yoga encourages a holistic understanding that integrates intellectual knowledge with experiential wisdom. This can lead to a more comprehensive approach to problem-solving, combining scientific rigor with ethical considerations and a deeper understanding of human consciousness.
https://g.co/gemini/share/
Further, see these 3 great Gemini AI replies in asking about Bhagavad Gita, its great battle, and regarding implications re Yoga too . . .
https://scott-macleod.
* * * *
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/scottmacleod/
AND
A flagship #WUaSbookstoreRoboticsStore with @WUaSPress #PublishingHouse in 7k languages on Bancroft Way in Berkeley near #UCBerkeleyCampus & for #WUaSoutreach to #CalGraduates for free #MITOCW-centric @WorldUnivAndSch #WUaSdegrees PhD. Law, MD & Master's https://scott-
https://x.com/TheOpenBand/
https://www.linkedin.com/
https://www.linkedin.com/
You'll find also URLs to 3 open storefront locations in Google Street View with time slider on Bancroft Way in Berkeley, right across from the UC Berkeley campus, potentially for the flagship physical digital WUAS Educational Services' Store for books, computers, robotics, groceries, hospital technologies too, - and from which Cal campus MIT OCW-centric would seek to recruit UC Berkeley graduates to matriculate at free-to-student's MIT OCW-centric WUaS and for free PhD, Law, MD, and Master's degrees from home, and in a realistic virtual earth for STEM field sites, and as classrooms + too.
https://www.linkedin.com/
https://www.linkedin.com/
| Sun, Jul 20, 5:48 PM (2 days ago) | ![]() ![]() | ||
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wuascorpceoclerk@
Education, Publishing, Academic Retail
http://
TAP Small Group Coaching
Q3 2025 Topic: Marketing Strategies for Small Business Growth
Brief Business/Organization Description:
The WUaS Corporation is a for profit general stock company legal entity in the state of California, (& the 2nd wing of 501 c 3 MIT OCW-centric wiki World University & School), for WUaS Educational Services Stores, an Academic Press @WUaS in 7K languages
14. Please elaborate on how you would like TAP to help:
World Univ & Sch / WUaS Corp is seeking TAP strategic and tactical advice to begin 1) to become financially operational 2) to hire Universitians on both wings-academics, retailers, translators & coders 3) to dev a business plan further for both WUaS wings
15. What are your top 3 goals for your business over the next year?
1) to become financially operational 2) to hire Universitians on both wings-academics, retailers, translators & coders with web platforms with AI and ML 3) to develop a business plan further for both WUaS wings, - particularly to help make some flagship Physical-Digital WUaS Educational Services' Stores operational (for books, computers, robotics, groceries, hospital technologies, planned in all 200 countries and in their main languages, and in a #RealisticVirtualEarth #
#MITOCW-centric wiki 1 @WorldUnivAndSch 2@WUaSPress #WUaSEducationalServicesStores -https://
-https://scott-macleod.
-https://
-https://scott-macleod.
HERE:
2548 Bancroft Way Berkeley:
https://www.google.com/maps/@
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/sgkmacleod/
https://www.linkedin.com/
https://www.linkedin.com/
https://www.linkedin.com/
MacLeod, Scott GK. 2025. A flagship #WUaSbookstoreRoboticsStore with @WUaSPress #PublishingHouse in 7k languages on Bancroft Way in Berkeley near #UCBerkeleyCampus & for #WUaSoutreach to #CalGraduates for free #MITOCW-centric @WorldUnivAndSch #WUaSdegrees PhD. Law, MD & Master's https://
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/scottmacleod/
AND A flagship #WUaSbookstoreRoboticsStore with @WUaSPress #PublishingHouse in 7k languages on Bancroft Way in Berkeley near #UCBerkeleyCampus & for #WUaSoutreach to #CalGraduates for free #MITOCW-centric @WorldUnivAndSch #WUaSdegrees PhD. Law, MD & Master's https://scott-
https://x.com/TheOpenBand/
https://x.com/HarbinBook/
Academic Press at WUaS and WUaS Educational Services' Stores (beginning web site) - http://
Moraga, CA: https://scott-macleod.
| 3:00 PM (5 hours ago) | ![]() ![]() | ||
|
-https://
-https://scott-macleod.
HERE:
2548 Bancroft Way Berkeley:
https://www.google.com/maps/@
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/sgkmacleod/
https://www.linkedin.com/
https://www.linkedin.com/
https://www.linkedin.com/
Tuesday, July 22, 2025
Indian hare: Oxford University Press publishes in 70 languages and 190 countries - regarding Academic Press at WUaS, planned in all 200 countries and in their main languages, and in all 7159 known living languages, with machine translation and human translation * * * Free Small Group Coaching Sessions Available : "Marketing Strategies for Small Business Growth" ~ The Acceleration Project (TAP) affiliated with JP Morgan Chase bank (which has operations in about 100 out of ~200 countries in the world) * * * Kaiser Permanente Oakland Medical Center Tue July 22, 2025 ... Thanks #JeffreyVelottaMD #ElaineLiang All for great talks today @ #KaiserPermanenteOakland & GREAT to meet you @JVelottaMD Let's talk further about #
Oxford University Press publishes in 70 languages and 190 countries - regarding Academic Press at WUaS, planned in all 200 countries and in their main languages, and in all 7159 known living languages, with machine translation and human translation.
AI Overview
Oxford University Press publishes in 70 languages and 190 countries. They are the largest university press in the world and publish a wide range of academic and professional content globally, according to their website. Their publishing program includes scholarly works, Bibles, music, textbooks, children's books, materials for teaching English, dictionaries, and academic journals
| 9:21 AM (1 hour ago) | ![]() ![]() | ||
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- How it works: A VPN encrypts your internet traffic and routes it through a server located outside China, masking your IP address and making it appear as though you're accessing the internet from a different location. This can effectively bypass the Great Firewall's restrictions.
- Challenges: The Chinese government actively detects and blocks VPNs, so only certain providers consistently work reliably in the country.
- Recommended VPNs: Based on recent testing, Comparitech recommends NordVPN as the most reliable VPN for China, highlighting its speed and ease of use. Other options include Surfshark, ExpressVPN, Hotspot Shield, and VyprVPN, all of which offer features designed to overcome the GFW, such as obfuscation or stealth protocols.
- Important Considerations:
- Download and install the VPN before traveling to China: Most VPN websites are blocked inside China, making it difficult to download the software once you're there.
- Choose a server location outside of China: For optimal results, connect to a server in a nearby country like Japan or Hong Kong.
- Stay updated: The GFW constantly updates its blocking mechanisms, so VPN software may require frequent updates to remain effective.
- Be aware of the risks: While using a VPN in China isn't explicitly illegal, the government cracks down on providers and may cut off internet access if a local provider detects VPN usage.
- Shadowsocks/WireGuard: These open-source proxies are designed to bypass censorship by mimicking regular HTTPS traffic, making them harder for the GFW to detect. Shadowsocks, in particular, uses the SOCKS5 protocol for traffic obfuscation.
- Tor with Bridges: While Tor is heavily blocked in China, using "bridges" (unlisted entry nodes) can sometimes allow access to the network. However, Tor connections tend to be slower and may not be reliable.
- Mobile Data with International Roaming: Roaming can create a tunnel to your home country's provider, assigning you an IP address not subject to Chinese censorship. However, this is generally the most expensive option.
- Web Proxies and Mirror Sites: Some blocked websites have mirror sites or proxy versions accessible in China. However, these can be unreliable and require constant searching for new links.
- Google Fi: This mobile service offers coverage in China, partnering with Unicom to potentially avoid data interception. It requires an eSIM and VPN activation from a US server.
| 6:16 AM (4 hours ago) | ![]() ![]() | ||
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Hi Scott,
What a pity, I can't open the link in China.
Best
--
何景明 博士,教授
茅台学院旅游管理系
贵州省仁怀市
邮编:564507
何景明 博士,教授
贵州师范大学国际旅游文化学院
贵州省贵阳市花溪大学城
邮编:550025
E-mail: hjm.11@163.com
Jingming HE,Professor
Department of Tourism Management,Maotai Institute
Renhuai City, Guizhou Province
P.R.China,564507
E-mail: hjm.11@163.com
Jingming HE,Professor
School of International Tourism & Culture, Guizhou Normal University,
Huaxi District,Guiyang City,Guizhou Province
P.R.China, 550025
E-mail: hjm.11@163.com
在 2025-07-28 12:32:16,"Scott MacLeod" <sgkmacleod@
*
https://en.wikipedia.org/wiki/Jasminum_grandiflorum
https://en.wikipedia.org/wiki/Jasmine
...
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