Friday, May 23, 2025

Acacia estrophiolata (an Ironwood tree species): What happens when you combine Google's #ArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules' w #GIsomorphicLabs to #AccelerateDrugDiscovery - for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in a #RealisticVirtualEarthForSyntheticBiology? * * * Re: Emerald Bay State Park F 5/23/25 - cell biologists' Suvrajit, and Madhuja, (Pin/Sid, Marti, Ed, Peter, Senator Warren), All, ... Fascinating to learn here too that Google's Calico Labs is tackling aging - https://www.calicolabs.com/ and Denali Therapeutics https://www.denalitherapeutics.com/home is focusing on regeneration




What happens when you combine Google's #ArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules' w  #GIsomorphicLabs to #AccelerateDrugDiscovery - for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in a #RealisticVirtualEarthForSyntheticBiology?


Combine #gArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts structure & interactions of all life’s molecules" w #GIsomorphicLabs to #AccelerateDrugDiscovery for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in #RealisticVirtualEarthForSyntheticBiology ...&?

https://x.com/WorldUnivAndSch/status/1925710062795854243

https://x.com/Q_YogaMacFlower/status/1925711230116794629

https://x.com/scottmacleod/status/1925710890860490863


https://x.com/TheOpenBand/status/1925715372226888135

https://x.com/HarbinBook/status/1925714888418062575

https://x.com/sgkmacleod/status/1925714529184321821

https://x.com/WUaSPress/status/1925713813002727569




Retweeting -

In @WorldUnivAndSch dev. a #RealisticVirtualEarthForAgingReversal w #AlphaFold3server "#AlphaFold3 predicts the structure and interactions of all of life’s molecules"
https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/#future-cell-biology (https://toolify.ai/ai-news/revolutionizing-education-with-machine-learning-and-ai-2574306 #ToolifyAIWUaS) https://fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/regenerative-medicine-advanced-therapy-designation How with
@DrCaliff_FDA ?

https://x.com/WorldUnivAndSch/status/1807385892941639993



Retweeting -

The first stage of the Neurona Therapeutics clinical trial is supported by CIRM.

Investigational therapies that receive RMAT designation are eligible to receive expedited development review and planning guidance from the
@US_FDA
.

Read more: https://neuronatherapeutics.com/news/press-releases/061824/

https://x.com/CIRMnews/status/1805644726445785378 ~





* * 

What happens when you combine Google's #ArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules' w  #GIsomorphicLabs to #AccelerateDrugDiscovery for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in a #RealisticVirtualEarthForSyntheticBiology?





* * 
How best to grow a #RealisticVirtualEarthForSyntheticBiology w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules'
https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/#future-cell-biology w #BenchlingForRandD
https://www.benchling.com/ for #AgingReversalGenetic & #ExtremeLongevityGenetic #drugTherapies?






* * 
Twitter - AlphaFold 3 predicts the structure and interactions of all of life’s molecules &  Benchling: Cloud-based platform for biotech R&D ...

AND see - 
Thursday, May 16, 2025 - 

Wednesday, May 14, 2025
Port Orford Cedar (Chamaecyparis lawsoniana): How best to grow a #RealisticVirtualEarthForSyntheticBiology w "#AlphaFold3 predicts ...







*

How best to grow a #RealisticVirtualEarthForSyntheticBiology w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules'
https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/#future-cell-biology w #BenchlingForRandD
https://www.benchling.com/ for #AgingReversalGenetic & #ExtremeLongevityGenetic #drugTherapies?

Benchling image - 







Googles ALPHAFOLD-3 Just Changed EVERYTHING! (AlphaFold 3 Explained)
https://youtu.be/W4_xG9sxX7A

The Benchling R&D Cloud
https://youtu.be/v7iyebOBAN8


As an example or place in an emerging realistic virtual earth - 




*
AlphaFold 3 predicts the structure and interactions of all of life’s molecules 







*
In @WorldUnivAndSch dev. a #RealisticVirtualEarthForAgingReversal w #AlphaFold3server "#AlphaFold3 predicts the structure and interactions of all of life’s molecules"



Languages WUaS - 







Retweeting -

The first stage of the Neurona Therapeutics clinical trial is supported by CIRM.

Investigational therapies that receive RMAT designation are eligible to receive expedited development review and planning guidance from the @US_FDA.









*
How best to interoperate "impact of modifying genes and proteins? 🧬" w a #RealisticVirtualEarthForGenes #RealisticVirtualEarthForProteins
@WorldUnivAndSch #WUaSunivs 
https://www.toolify. ai/ai-news/revolutionizing-education-with-machine-learning-and-ai-2574306 
-#ToolifyAIWUaS w https://blog. google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/#future-cell-biology think #GstreetView w #TimeSlider #GAtomView ?
https://twitter. com/scottmacleod/status/1796502507575025975 

https://twitter. com/WorldUnivAndSch/status/1796502696910012679 

https://twitter. com/TheOpenBand/status/1796503322985460072 

https://twitter. com/sgkmacleod/status/1796503237778141566 

https://twitter. com/HarbinBook/status/1796503144375230473 

https://twitter. com/WUaSPress/status/1796502812538650981 



Retweeting - 

What is the impact of modifying genes and proteins? 🧬

We're developing the #opensource Perturbation Catalogue to answer this, integrating harmonised and curated gene, variant, and expression data

Are you a postdoc or full stack dev? Help us build this!

https://twitter. com/OpenTargets/status/1796148051146313846. ... to https://wiki.worlduniversityandschool. org/wiki/Virtual_Worlds and https://wiki.worlduniversityandschool. org/wiki/Aging_Reversal_Genetics and https://wiki.worlduniversityandschool. org/wiki/Open_Access_Resources (from https://wiki.worlduniversityandschool. org/wiki/Subjects)







*
How best to interoperate "impact of modifying genes and proteins? 🧬" w a #RealisticVirtualEarthForGenes #RealisticVirtualEarthForProteins
@WorldUnivAndSch #WUaSunivs 







Retweeting - 

What is the impact of modifying genes and proteins? 🧬

We're developing the #opensource Perturbation Catalogue to answer this, integrating harmonised and curated gene, variant, and expression data

Are you a postdoc or full stack dev? Help us build this!







A #RealisticVirtualEarthFor #AgingReversalMachine too? Thnx #PeterNorvig for #ToolifyAI WOW! article: 
"#RevolutionizingEducation w #MachineLearning & AI" : @WorldUnivAndSch #WUaSunivs 



*

A #RealisticVirtualEarthFor #AgingReversalMachine too? Thnx #PeterNorvig for #ToolifyAI WOW! article: 
"#RevolutionizingEducation w #MachineLearning & AI" : @WorldUnivAndSch #WUaSunivs 











*


WOW: "#AlphaFold3 takes us beyond proteins to a broad spectrum of biomolecules. This leap could unlock more transformative science" - to accelerate #WUaSDrugDesign & #WUaSgenomics research"-Steps to #RealisticVirtualEarthFor #ForProteins #ForPharmaceuticals #AgingReversalMachine?







Retweeting - 

1.8M+ researchers have used @GoogleDeepMind’s AlphaFold protein predictions in their work on vaccine development, cancer treatment + more. AlphaFold 3 is the latest breakthrough, predicting the structures + interactions of all of life’s molecules with unprecedented accuracy. We’re sharing access to these capabilities through AlphaFold Server to enable other scientific discoveries. blog.google/technology/ai/




*
AlphaFold 3 predicts the structure and interactions of all of life’s molecules
May 08, 2024


Introducing AlphaFold 3, a new AI model developed by Google DeepMind and Isomorphic Labs. By accurately predicting the structure of proteins, DNA, RNA, ligands and more, and how they interact, we hope it will transform our understanding of the biological world and drug discovery.



G
Google DeepMind AlphaFold team
I
Isomorphic Labs


AND 

In what ways @HankGreelyLSJU @johncumbers All could #AlphaFold3 be emerging #CSvocabulary to also predict #GeneExpression  -https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model/#future-cell-biology & in building a #RealisticVirtualEarthForGenetics >https://www.toolify.ai/ai-news/revolutionizing-education-with-machine-learning-and-ai-2574306 eg in #GStreetView w #TimeSlider #GCellView #GAtomView ?








Retweeting - 

Another indication of the complexity of gene expression, in this case in regard to splicing. My sense in this (very interesting) paper is that we still lack the vocabulary to talk about the organizational and spatiotemporal processes here. #HowLifeWorks 





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Society, Information Technology, and the Global University (2025, forthcoming) 

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- USPS US Post Office, General Delivery, Canyon, CA 94516 


1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 
 World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com 



 



* * * 

How best could
#WorldUniversitians @WorldUnivAndSch help to build the #WUaSMultimediaHospitalRoom in #Canyon94516shop w #GoogleBeams' 6 video cameras on smartphone -https://www.pcmag.com/news/googles-futuristic-beam-tech-almost-made-me-forget-i-was-on-a-video-call @ #GcellView & #GmoleculeView levels? #GGoogleIO25 was awesome -https://blog.google/technology/ai/google-io-2025-all-our-announcements/ ~


How best could
#WorldUniversitians @WorldUnivAndSch help to build the #WUaSMultimediaHospitalRoom in #Canyon94516shop w #GoogleBeams' 6 video cameras on smartphone -https://www.pcmag.com/news/googles-futuristic-beam-tech-almost-made-me-forget-i-was-on-a-video-call @ #GcellView & #GmoleculeView levels? #GGoogleIO25 was awesome -https://blog.google/technology/ai/google-io-2025-all-our-announcements/ ~















Society, Information Technology, and the Global University (2025, forthcoming) 

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- USPS US Post Office, General Delivery, Canyon, CA 94516 


1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 
 World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com 




* * * 

Re: Emerald Bay State Park F 5/23/25

 - cell biologists' Suvrajit, and Madhuja, (Pin/Sid, Marti, Ed, Peter, Senator Warren), All, ... Fascinating to learn here too that Google's Calico Labs is tackling aging -

https://www.calicolabs.com/ and Denali Therapeutics https://www.denalitherapeutics.com/home is focusing on regeneration


Suvrajit, and Madhuja, (Pin/Sid, Marti, Peter, Senator Warren), All, 

Great to meet and talk with you Suvrajit, and Madhuja and learn that you're cell biologists /similar (and from Kolkata/Calcutta, India, about 10 years ago). .. The picture attached I think ... 

Fascinating to learn here too that Google's Calico Labs is tackling aging -

In what ways could you both, Suvrajit, and Madhuja, and with Calico Labs (and Denali Therapeutics https://www.denalitherapeutics.com/home too?) and MIT OCW-centric wiki World Unic & Sch WUaS and I best develop a physical-digital #RealisticVirtualEarth #ForGeneritcs And #ForAgingReversal (#Twitter / X) AND in the shop in 670 Ridgecrest Rd Canyon 94516 in the SF East Bay where I am based?

Looking forward to communicating further about this 

All the best, Namaste, thanks,
Scott 
Will add this email thread here to yesterday's F 5/23/25 daily blog post - 



PS 
found 





PPS








PPS
BRAINSTORMING - 

How best could
#WorldUniversitians @WorldUnivAndSch help to build the #WUaSMultimediaHospitalRoom in #Canyon94516shop w #GoogleBeams' 6 video cameras on smartphone -https://www.pcmag.com/news/googles-futuristic-beam-tech-almost-made-me-forget-i-was-on-a-video-call @ #GcellView & #GmoleculeView levels? #GGoogleIO25 was awesome -https://blog.google/technology/ai/google-io-2025-all-our-announcements/ ~










On Fri, May 23, 2025 at 7:02 PM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote:
Suvrajit Saha,
Madhuja Samaddar,

Very nice to meet you here!

Namaste!, 
Scott



What happens when you combine Google's #ArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts the structure & interactions of all of life’s molecules' w  #GIsomorphicLabs to #AccelerateDrugDiscovery - for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in a #RealisticVirtualEarthForSyntheticBiology?


Combine #gArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts structure & interactions of all life’s molecules" w #GIsomorphicLabs to #AccelerateDrugDiscovery for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in #RealisticVirtualEarthForSyntheticBiology ...&?












Retweeting -

In @WorldUnivAndSch dev. a #RealisticVirtualEarthForAgingReversal w #AlphaFold3server "#AlphaFold3 predicts the structure and interactions of all of life’s molecules"
@DrCaliff_FDA ?




Retweeting -

The first stage of the Neurona Therapeutics clinical trial is supported by CIRM.

Investigational therapies that receive RMAT designation are eligible to receive expedited development review and planning guidance from the
@US_FDA
.






Society, Information Technology, and the Global University (2025, forthcoming) 

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- USPS US Post Office, General Delivery, Canyon, CA 94516 


1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 
 World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com 




* * 

Wednesday, May 28, 2025

Suvrajit, and Madhuja, (Pin/Sid Maxumdar HHS, Marti Mazumdar MD - HMS, Ma/Janie MacLeod, Ed Smyth MD, Peter Norvig Google AI Director, Profs David Sun Kong & George Church, Senator and former Harvard Law Professor Elizabeth Warren), All, 

Great to meet and talk with you at Emerald Bay State Park near Lake Tahoe, Suvrajit, and Madhuja. Your mentioning 23 and Me (once? affiliated with Google -
[While] Google did invest in 23andMe, according to Fierce Biotech and TechCrunch, it remained an independent company. Google co-founder Sergey Brin's wife, Anne Wojcicki, co-founded 23andMe and was its CEO for many years. Google's investment was a strategic move to support the company's mission of personalizing genetics and health data, according to Fierce Biotech and was consistent with Google's broader goals of organizing information and understanding human biology. 
Here's a more detailed explanation:
  • Google's Investment:
    In 2007, Google invested $3.9 million in 23andMe, along with other investors like Genentech, New Enterprise Associates, and Mohr Davidow Ventures, according to Wikipedia and TechCrunch. 
  • Independent Company:
    Despite Google's investment, 23andMe remained a separate entity and was never a subsidiary or part of the Google family of companies. 
  • Anne Wojcicki's Role:
    Anne Wojcicki, who was married to Google co-founder Sergey Brin at the time of the investment, was the co-founder and CEO of 23andMe, leading the company's development and growth. 
  • Strategic Alignment:
    Google's investment in 23andMe was seen as a way to support the company's vision of providing individuals with access to their genetic information and connecting it with their health and ancestry. 
  • Focus on Drug Research:
    23andMe also partnered with Google on research related to drug discovery and development, leveraging their large DNA database for insights into new therapies. 
  • Current Status:
    While Google is no longer a major investor in 23andMe, the company continues to operate as an independent entity, focusing on personal genomics, health research, and ancestry services. 

) AND with Calico Labs being a Google company ...  leads me to wonder both about developing, With both of these companies, a N-Dimensional Physical-Digital high-performance Realistic Virtual Earth for Synthetic Biology, For Aging Reversal too, in the shop at 670 Ridgecrest  Canyon 94516 (and also even seeking a life partner re 23 and Me (who might also be interested in becoming a MD and starting a family too:). How best could World Univ & Sch focus somehow https://en.wikipedia.org/wiki/23andMe in the direction of personal Aging Reversal and Extreme Longevity genetics  and gene drug therapies ... Possibly for related 23 & Me readouts Over the very long future ahead for example AND in esp with combining  "#gArtificialGeneralIntelligence #DeepMind w "#AlphaFold3 predicts structure & interactions of all life’s molecules" w #GIsomorphicLabs to #AccelerateDrugDiscovery for #AgingReversal & #ExtremeLongevity #GeneDrugTherapies in #RealisticVirtualEarthForSyntheticBiology ..." - https://scott-macleod.blogspot.com/2025/05/acacia-estrophiolata-ironwood-species.html  - with 23 and Me's large customer base of over 15 million individuals, (according to 23andMe). Thoughts? Whare are Calico Labs and Denali Therapeutics heading in tackling Aging and Regeneration?  

Looking forward to staying in touch, All the best, thank you,
Scott  



PS
Know of any related courses -





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https://apps.lucidcentral.org/wattle/text/entities/acacia_estrophiolata.htm




https://en.wikipedia.org/wiki/Ironwood

https://commons.wikimedia.org/wiki/Acacia_estrophiolata



...


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