Sunday, May 4, 2025

Batocera wallacei (& Longhorn beetle): EHR Electronic Health Records for species including #Drosophila and genetics - How? #AvatarAgentElectronicHealthRecords for genetics eg 'Fly with legs in place of antennae, caused by #AntennapediaMutation' with implications for #AgingReversal & #ExtremeLongevity #GeneTherapies ~

 

EHR Electronic Health Records for species including #Drosophila and genetics - How? ,,,


EHR Electronic Health Records for species including #Drosophila and genetics - How? #AvatarAgentElectronicHealthRecords for genetics eg 'Fly with legs in place of antennae, caused by #AntennapediaMutation' with implications for #AgingReversal & #ExtremeLongevity #GeneTherapies ~



EHR for species including #Drosophila - How? #AvatarAgentElectronicHealthRecords for genetics eg 'Fly with legs in place of antennae, caused by #AntennapediaMutation'
with implications for #AgingReversal & #ExtremeLongevity #GeneTherapies ~









"Fly with legs in place of antennae, caused by Antennapedia mutation" picture - 
https://en.m.wikipedia.org/wiki/File:Antennapedia2.jpg



searched on 
antennae genetics drosophila wings


Drosophila (fruit flies), the Antennapedia (Antp) gene is crucial for determining the identity of body segments, and mutations in its regulatory region can lead to ectopic antennae development in place of legs. Specifically, a loss-of-function mutation in Antp can cause the second leg pair to transform into antennae. Conversely, the homothorax (hth) and extradenticle (exd) genes are involved in specifying antennal identity, and their loss-of-function can lead to leg development in the antenna. 
Antennapedia (Antp) and its role in segment identity:
  • Hox genes: Antp is a member of the Hox gene family, which are master regulators of body segmentation in animals. 
  • Leg vs. Antenna: Antp promotes leg development by repressing antennal-determining genes. 
  • Mutations and transformations: Mutations in Antp can lead to ectopic antenna development in place of legs. 
Homothorax (hth) and Extradenticle (exd) and their role in antennal identity:
  • Antennal-determining genes: hth and exd are identified as antennal-determining genes.
  • Loss-of-function and transformations: Loss-of-function mutations in hth or exd can transform the antenna into a leg.
  • Antp's repression: Antp is a repressor of hth, suggesting that Antp's activity helps maintain the leg identity. 
Other genes and their roles in antenna development:
  • Hernandez and Fernandez: These genes are involved in specifying both antenna and eye development. 
  • Engrailed: The engrailed gene is important for patterning the eye-antenna imaginal disc. 
  • Cut: Mutations in the cut gene can lead to abnormalities in the antenna, including the loss of sensory bristles. 
In summary, the development of antennae in Drosophila is a complex process involving multiple genes, including the Hox gene Antp, the antennal-determining genes hth and exd, and other genes involved in patterning and development. 


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A DNA mutation is a permanent change in the DNA sequence of an organism. These changes can occur due to errors during DNA replication, exposure to mutagens (like radiation or chemicals), or even spontaneously. Mutations are essential for genetic variation and evolution. 


re
Deoxyribonucleic Acid 






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https://en.wikipedia.org/wiki/Batocera_wallacei

https://commons.wikimedia.org/wiki/Category:Batocera_wallacei




https://en.wikipedia.org/wiki/Longhorn_beetle

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