Scott MacLeod's Anthropology of Information Technology & Counterculture
To a global, virtual, free, open, {future degree- & credit-granting}, multilingual University & School for the developing world and everyone, as well as loving bliss ~ scottmacleod.com
Thnx #ProfDavidSinclair & @thecrimson @Harvard for #AgingReversal art. https://www.thecrimson.com/article/2025/2/7/david-sinclair-fifteen-questions/ & corey.becker@thecrimson.com, & Great to see #CoreyBeckerHarvardPhysics that you went to Quaker @FriendsSelect_'22 >#QuakerInformed #freeWUaS @WorldUnivAndSch https://wiki.worlduniversityandschool.org/wiki/Aging_Reversal_Genetics ~
McKenna E. McKrell is the President of the 152nd Guard of The Harvard Crimson. She can be reached at mckenna.mckrell@thecrimson.com. Follow her on X @mckenna_mckrell.
Thnx @geochurch for retweet & re "Nabla Bio’s AI design AND human-relevant wet-lab capabilities" &
re a #PhysicalDigital 'conversation' & also a #RealisticVirtualEarth with AI
Thnx @geochurch for retweet & how best could @WorldUnivAndSch dev a #RealisticVirtualEarthForProteins #ForAgingReversal re "Nabla Bio’s AI design and human-relevant wet-lab capabilities" to deploy "across Takeda’s early-stage development programs" w #WUaSunivs collab w both cos?
We’re excited to share a new multi-year collaboration with @TakedaPharma, building on the success of our first engagement. Under the agreement, Nabla will receive double-digit millions in upfront and research payments and is eligible for success-based payments exceeding $1 billion.
The partnership deploys Nabla’s AI-driven JAM platform across Takeda’s early-stage programs to include de novo design of antibodies in parallel for multiple targets, multispecifics, challenging targets, and other custom therapeutics.
Read more below
We’re excited to share a new multi-year collaboration with @TakedaPharma, building on the success of our first engagement. Under the agreement, Nabla will receive double-digit millions in upfront and research payments and is eligible for success-based payments exceeding $1…
"Nabla Bio’s AI design and human-relevant wet-lab capabilities"
"Multi-year partnership deploys Nabla Bio’s AI design and human-relevant wet-lab capabilities broadly across Takeda’s early-stage development programs"
& regarding especially a #PhysicalDigital #ActualVirtual #RealisticVirtualEarth (and see #PeterNorvig's INCREDIBLE #ToolifyAIWUaS article - https://www.toolify.ai/ai-news/revolutionizing-education-with-machine-learning-and-ai-2574306 - mentioning a realistic virtual earth for the first time other than by #WorldUnivAndSch) ... #ForGeneticDrugTherapies #ForPharmacology #ForGenetics #ForExtremeLongevity #GeneticDrugTherapies #RealisticVirtualEarthForClinicalTrials #RealisticVirtualEarthFor (& think #GStreetView with #GTimeSlider with #GMaps #TensorFlowAI #AlphaFold3Server and where little Pegman becomes our #AvatarAgentElectronicHealthRecords & for all 7.9 Billion of us @ https://wiki.worlduniversityandschool.org/wiki/You_at_World_University
@ #MITOCWcentric wiki #WorldUniversityAndSchool)+
. . .
We’re excited to share a new multi-year collaboration with @TakedaPharma, building on the success of our first engagement. Under the agreement, Nabla will receive double-digit millions in upfront and research payments and is eligible for success-based payments exceeding $1 billion.
The partnership deploys Nabla’s AI-driven JAM platform across Takeda’s early-stage programs to include de novo design of antibodies in parallel for multiple targets, multispecifics, challenging targets, and other custom therapeutics.
Nabla Bio’s AI design AND human-relevant wet-lab capabilities
Thnx @geochurch for retweet & how best could @WorldUnivAndSch develop a #RealisticVirtualEarthForProteins#ForAgingReversal re
"Nabla Bio’s AI design and human-relevant wet-lab capabilities" to deploy "across Takeda’s early-stage development programs" with #WUaSunivs collaborating w both companies?
We’re excited to share a new multi-year collaboration with @TakedaPharma, building on the success of our first engagement. Under the agreement, Nabla will receive double-digit millions in upfront and research payments and is eligible for success-based payments exceeding $1 billion.
The partnership deploys Nabla’s AI-driven JAM platform across Takeda’s early-stage programs to include de novo design of antibodies in parallel for multiple targets, multispecifics, challenging targets, and other custom therapeutics.
"Nabla Bio’s AI design AND human-relevant wet-lab capabilities"
"Multi-year partnership deploys Nabla Bio’s AI design and human-relevant wet-lab capabilities broadly across Takeda’s early-stage development programs"
& regarding especially a #PhysicalDigital#ActualVirtual#RealisticVirtualEarth (and see #PeterNorvig's INCREDIBLE #ToolifyAIWUaS article - https://www.toolify. ai/ai-news/revolutionizing-education-with-machine-learning-and-ai-2574306 mentioning a realistic virtual earth for the first time other than by #WorldUnivAndSch) ... #ForGeneticDrugTherapies#ForPharmacology#ForGenetics#ForExtremeLongevity#GeneticDrugTherapies#RealisticVirtualEarthForClinicalTrials#RealisticVirtualEarthFor (& think #GStreetView with #GTimeSlider with #GMaps#TensorFlowAI#AlphaFold3Server and where little Pegman becomes our #AvatarAgentElectronicHealthRecords & for all 7.9 Billion of us @ https://wiki.worlduniversityandschool. org/wiki/You_at_World_University = https://wiki.worlduniversityandschool.org/wiki/You_at_World_University @ #MITOCWcentric wiki #WorldUniversityAndSchool)+
Marburg University in Germany which is tuition-free (in #InformationAge) & @WorldUnivAndSch collaboration? - Twitter
A Realistic Virtual Earth for everything for Sports as sandbox to start with - and for languages esp ... and re Germany World University and School, eventually as Deutschland World University and School in German ...
is "a public research univ in Marburg, Germany (1527), the world's oldest operating Protestant univ, known for research & offers tuition-free education for students" How could #MITOCWcentric wiki @WorldUnivAndSch collab?
Marburg Univ (in #InformationAge) -https://t.co/vMdpDQUcot is "a public research univ in Marburg, Germany (1527), the world's oldest operating Protestant univ, known for research & offers tuition-free education for students" How could #MITOCWcentric wiki @WorldUnivAndSch collab?
is "a public research university in Marburg, Germany (1527), the world's oldest operating Protestant university, known for research & offers tuition-free education for students" - How could #MITOCWcentric wiki @WorldUnivAndSch collaborate ?
Marburg University (Philipps-Universität Marburg) is a public research university in Marburg, Germany, founded in 1527. It is one of Germany's oldest universities and the world's oldest operating Protestant university. It has a wide range of programs, is known for research, and offers tuition-free education for students
The philosophy of Indian Classical Music, particularly the Raga system (as heard with instruments like Sitar, Sarod, and Tabla), is a profoundly deep and holistic framework that extends far beyond mere notes and scales. It is rooted in ancient spiritual and aesthetic texts and can be extrapolated to many modern philosophical concepts.
Here is an in-depth, extrapolative, and brainstorming look at its core philosophy:
I. The Core Philosophical Pillars
1. The Divine Nature of Sound (Nada Yoga)
Core Concept: The ultimate reality is sound (Nada Brahma—"Sound is God/Brahman"). Music is not just entertainment but a path to spiritual realization (Moksha).
Acoustic Manifestation: The Tanpura (drone instrument) embodies this. It continuously produces the fundamental tone (Sa) and the perfect fifth (Pa), representing the eternal, unchanging foundation (Brahman) from which all other sounds (the Raga, the manifested world) emerge.
Extrapolation (Modern): This mirrors the philosophical idea of a unified field or the fundamental "vibration" of the universe (similar to string theory or quantum fields). The performance is an act of contemplative practice, a form of mindfulness where the musician and listener try to dissolve the ego into the universal drone.
2. Emotion and Consciousness (Rasa)
Core Concept: The word Raga itself comes from the Sanskrit root ranj, meaning "to color" or "to tinge the mind." The goal of a Raga is to evoke a specific, pure emotional state or aesthetic flavor (Rasa) in the listener. There are nine primary Rasas (e.g., love, sorrow, courage, peace).
Acoustic Manifestation: The specific combination of notes (swaras), the emphasis on the vadi (king note) and samvadi (prime minister note), and the unique melodic phrases (pakad) all combine to "color" the consciousness.
Extrapolation (Modern): This is a philosophy of Cognitive Resonance. The Raga is a structured emotional algorithm designed to synchronize the human nervous system with a pre-defined feeling. It suggests that music is a direct technology for emotional engineering, far more specific than Western modes.
3. The Interconnectedness of Time and Nature
Core Concept: Many Ragas are assigned a specific time of day (Samay) or season, known as the Time Theory of Raga. Playing a Raga at its designated time is believed to maximize its emotional and spiritual impact by aligning the music with the natural energy and human circadian rhythms.
Acoustic Manifestation:
Morning Ragas (like Bhairav) often use flat notes and a lower tessitura, evoking the solemn, meditative quality of dawn.
Evening Ragas (like Yaman) use sharp, high-tension notes to capture the transition and romantic energy of twilight.
Extrapolation (Brainstorming): This is a philosophy of Deep Ecology and Chronobiology. It views music not as a standalone art, but as a dynamic component of the universal clock. The music is a sonic calendar, reminding humanity that it is part of a larger, rhythmic universe.
II. The Philosophy of Performance (Improvisation)
4. The Journey of Exploration (Alap, Jor, Jhala)
Core Concept: A classical performance is not the recreation of a fixed composition but the unfolding and discovery of a Raga's potential. It is an improvised journey from the absolute (the drone) to the realized (the final melody).
Acoustic Manifestation:
Alap: The slow, unaccompanied, meditative introduction that systematically introduces the notes of the Raga, note by note, phrase by phrase, establishing the mood. (Pure melody, no rhythm).
Gat/Bandish: The composed, fixed part that acts as a reference point for improvisation.
Tala (Rhythmic Cycle): The Tabla provides the rhythmic scaffolding (e.g., Teentaal - a 16-beat cycle), offering a mathematical yet fluid structure for the melodic exploration.
Extrapolation (Modern): This is a model for Existential Freedom within Structure. The Raga is the law, but the performance is freedom—the artist demonstrates the ability to be completely creative while strictly adhering to the fundamental rules. The slow opening (Alap) is the ultimate practice of delayed gratification and patient immersion.
5. The Guru-Shishya Parampara (Oral Tradition)
Core Concept: Knowledge is passed down through a living, oral tradition from a master (Guru) to a student (Shishya). The relationship is not just transactional but deeply spiritual, focusing on technique, philosophy, and moral discipline.
Extrapolation (Brainstorming): This emphasizes the concept of Embodied Knowledge. The music is not a text to be read (like a Western score) but a living being that must be internalized. The master's unique way of delivering a note (a microtone or shruti) is the crucial, un-notatable component—a rejection of pure textual authority in favor of lived, personal experience.
III. Extrapolations and Brainstorming
Raga Element
Philosophical Concept
Modern Extrapolation
Microtones (Shrutis)
Nuance as Reality
The philosophy of fine-grained detail. The "in-between" spaces (not the notes themselves) are what give the music its emotional specificity, implying that true reality/emotion lies in the subtle gradients, not the clear-cut binaries.
Improvisation
Flow State / Being in the Moment
The ultimate practice of present-moment awareness and real-time risk-taking. The musician must create spontaneously while honoring centuries of tradition—a perfect balance of Chaos and Order.
The Tala (Rhythm)
Cyclical Time
A rejection of linear, Western-style progressive time. Time is a closed loop that the musician constantly returns to (Sam - the first beat). This mirrors concepts of cosmic cycles (e.g., Yugas).
Solo-Focus
The Universe in a Single Line
A philosophy of monophonic focus. Unlike harmony which distributes attention across multiple lines, Raga requires all focus on the single, perfect, developing melodic line—a metaphor for focusing one's spiritual or intellectual energy on a single goal.
Scott's an anthropologist of #PhysicalDigital Harbin Hot Springs' Heart Consciousness Church @HarbinBook (on #TwitterX), as ethnographic field site - https://goo.gl/maps/7gSsSTweRCBo9gf87 - who also finds fascinating the internet, ideas, poetry, sociology, art, science, genetics of aging reversal and extreme longevity drug therapies emerging (with FDA approval), philosophy, history, music, love and life ~ as well as the anthropology of information technology & counterculture :) - scottmacleod.com ... Am also the president or head of, and professor at, MIT OCW-centric wiki World Univ & Sch & Academic @WUaSPress, planned in 7,159 living languages with machine translation, aka the WUaS Corp) planning free online degrees in ~200 countries & in their main languages, where you can #WikiTeach, or #WikiLearn, or #WikiCreate - https://wiki.worlduniversityandschool.org/wiki/Subjects (see too: http://www.scottmacleod.com/yoganotations.html in exploring questions of Yoga & wisdom?). Identity-wise, a Nontheist f/Friendly Quaker - a NtF or NtQ - with Unitarian Universalist sympathies as well, and a player of Scottish bagpipes, and an academic '~India is eternally fascinating~
.jpg?20091209125059)
.jpg/1600px-Ranunculus_glacialis_(flower).jpg?20080803143338)
.jpg/1600px-Ranunculus_glacialis_(habitus).jpg?20080803143235)
Posts
![Neelakurinji (Strobilanthes kunthiana): Becker, Corey. 2025. [https://www.thecrimson.com/article/2025/2/7/david-sinclair-fifteen-questions/ Fifteen Questions: David Sinclair on Age Reversal, Exercise, and Immortal Yeast Cells]. Cambridge, MA: https://www.thecrimson.com. added to https://wiki.worlduniversityandschool.org/wiki/Aging_Reversal_Genetics .](https://upload.wikimedia.org/wikipedia/commons/3/3b/Neelakurinji_%28Strobilanthes_kunthiana%29_%28259372738%29.jpg?20121204003339){kind=link}
