Mark, Tammie, Janie, Byron,
Happy gene-day (nee birthday) today further, Mark, now on January 27 2026. (Every day is a gene day, n'est-ce pas?:)
Just submitted an extended abstract to give a paper at the Univ of Glasgow at a Social Media and Society conference between M July 13-15
http://scott-macleod.blogspot.
Made first contact about this via the AoIR list with a Harry Dyer at the University of East Anglia, whose last name is the same as a well known Quaker from the 1650s in Boston, Mary Dyer ... and re your father, a favorite uncle of mine, Bruce Vincent MacLeod's Quakerism, and search on Dyer here - https://scott-macleod.
So it's possible I'll be heading to Scotland then. I noticed, Mark, you're doing genetic genealogy at the MacLeod Parliament again this August 1-7 on the Isle of Skye -
https://www.clanmacleod.org/
In these regards, and with you great knowledge of genetic genealogy, and genealogy, and MacLeod genealogy especially, am wanting to grow my WikiTree genealogy platform knowledge and skills (who were my Grandpa's Sandy Brown's Scottish ancestors - https://www.wikitree.com/
In some of these regards, I asked Gemini AI about all these genealogy platforms, re genetic genealogy, too, and learned something, and see PSs.
Mark, I may seek to stay with Friends / Quakers in Glasgow or Edinburgh when and if I give my Society, Info Tech and Global Univ paper; where would you suggest staying on Skye or Raasay or similar during the MacLeod Parliament? (I think there's an unprogrammed Quaker Meeting on Skye that may meet once a month of similar ... and I may somehow seek to inquire there re possible hospitality too).
(Am continuing to seek to move into a newly safe vacant with property deed 670 Ridgecrest Rd, Canyon 94516 soonish, and with US federal law and state of CA law working effectively together in new ways).
Tammie are you hosting the MacLeod tent at the 160th! Caledonian Highland Games again this year in Pleasanton on 9/5 &6?
Warm regards, Hold fast, abolition, best wishes,
Scott
blogged about some of this genealogy with genetics before here, with a MacLeod parliament photo from the 1950s, - and may add this email too here:
https://scott-macleod.
https://scott-macleod.
https://scott-macleod.
https://scott-macleod.
PS
1
How sophisticated is the wiki tree genealogy platform for genetics for genealogical genetics?
https://g.co/gemini/share/
2
How sophisticated is ancestry.com for genealogical data and for genealogy genetically?
https://g.co/gemini/share/
3
How sophisticated is the genealogy platform 23andMe for genetic genealogy
https://g.co/gemini/share/
4
How best to interoperate the genealogy platforms of Wiki tree and ancestry.com and 23andMe if at all possible. What are some interesting examples of this? Is there a fourth platform that might integrate them?
https://g.co/gemini/share/
5
Can I use gedmatch GED match for genealogy genetics and as a genealogy platform ?
https://g.co/gemini/share/
PPS
Expanded with Gemini responses -
1
How sophisticated is the wiki tree genealogy platform for genetics for genealogical genetics?
WikiTree is highly sophisticated for collaborative verification, though it operates differently than major testing sites. Instead of performing direct DNA matching, it acts as a metadata hub where users link their test results to specific tree profiles.
Key Genetic Features
DNA Test Connections: When you link a test (AncestryDNA, Y-DNA, etc.), WikiTree automatically places "DNA Connection" badges on your ancestors' profiles up to 8 generations back.
Relationship Finder: A powerful tool that calculates all possible paths of descent between two users to identify where shared DNA segments likely originated.
DNA Confirmation: This is its most unique feature. It uses a peer-reviewed "DNA Confirmation" system where users must provide specific evidence (like triangulation or X-chromosome matching) to mark a relationship as scientifically "confirmed."
Targeted Testing: The platform helps identify specific living descendants who carry a certain ancestor's Y-DNA or mtDNA, aiding in strategic testing to break through "brick walls."
The Caveat
WikiTree does not host raw DNA data. You cannot upload a genome file there for matching. Instead, you use it to organize and prove the paper-trail connections to matches you found on sites like Ancestry or GEDmatch.
Would you like me to find the specific steps for adding your DNA test information to a WikiTree profile
https://g.co/gemini/share/
2
How sophisticated is ancestry.com for genealogical data and for genealogy genetically?
Ancestry.com is the industry leader in both historical records and genetic genealogy.
Genealogical Data
Scale: Hosts over 60 billion records and 130 million family trees, making it the world’s largest commercial repository.
Searchability: Sophisticated indexing and "Hints" use AI to cross-reference your tree with census, military, and vital records.
Specificity: Offers deep geographic granularity, especially for North American and European lineages.
Genetic Genealogy
Database: Boasts the largest consumer DNA database (over 25 million users), maximizing your chances of finding "DNA matches" (relatives).
Precision: Uses autosomal DNA to identify over 3,600 genetic regions, often pinpointing specific sub-regions or migration patterns.
Integration: Uniquely links DNA results with historical trees (via ThruLines), allowing you to see exactly how you are related to a match.
Note: While excellent for finding relatives and ethnicity, Ancestry is less sophisticated for health data compared to competitors like 23andMe, as they discontinued their dedicated health reporting in 2021.
Would you like me to compare Ancestry's pricing tiers or help you decide which DNA kit fits your goals
https://g.co/gemini/share/
3
How sophisticated is the genealogy platform 23andMe for genetic genealogy?
23andMe is highly sophisticated for biological ancestry, though it trails competitors like AncestryDNA for traditional genealogical records.
Key Strengths
Deep Lineage: It is the only major "all-in-one" kit that provides both maternal and paternal haplogroups (mtDNA and Y-DNA) alongside autosomal results.
Precision: As of 2026, it offers a granular breakdown of 4,500+ geographic regions, often pinpointing ancestry to the 0.1% level.
Chromosome Browser: Unlike AncestryDNA, 23andMe provides a built-in chromosome browser, allowing you to see exactly which segments of DNA you share with matches.
Limitations
Smaller Database: With roughly 15 million users, its "DNA Relative" pool is smaller than Ancestry’s (25 million+).
Fewer Records: While they've added a "Records & Archives" feature, they lack the massive library of census, birth, and death records found on dedicated genealogy sites.
Financial Stability: The company’s recent bankruptcy filing and past data leaks have raised concerns regarding long-term data security and service continuity.
Would you like me to compare its current privacy policies with other major DNA testing services
https://g.co/gemini/share/
4
How best to interoperate the genealogy platforms of Wiki tree and ancestry.com and 23andMe if at all possible. What are some interesting examples of this? Is there a fourth platform that might integrate them?
Interoperating these platforms is highly effective for combining DNA data with deep historical records. Because Ancestry and 23andMe are "walled gardens" (they don't share data directly), you must use third-party bridges to connect them.
Best Ways to Interoperate
GEDmatch (The DNA Bridge): Download your raw DNA data from Ancestry and 23andMe, then upload both to GEDmatch. This allows you to compare matches from different companies in one database.
WikiTree DNA Tags: You cannot upload raw DNA to WikiTree, but you can list your GEDmatch ID and test details on your profile. WikiTree then automatically propagates this information to your ancestors' profiles, showing other researchers which branches have been DNA-verified.
WikiTree X: Use this browser extension to quickly "clip" source data and person profiles from Ancestry and FamilySearch directly into WikiTree.
Interesting Examples of Use
Triangulation: A user finds a DNA match on 23andMe but has no tree for them. By finding that same match on GEDmatch, they link to the match’s WikiTree profile, which reveals a shared 4th-great-grandfather not documented on Ancestry.
Chromosome Mapping: Using segment data from 23andMe and GEDmatch, users use DNA Painter to "paint" which specific segments of their DNA came from which WikiTree-verified ancestor
https://g.co/gemini/share/
5
Can I use gedmatch GED match for genealogy genetics and as a genealogy platform ?
Yes, you can use GEDmatch for both genetic analysis and genealogical research, though it functions differently than sites like Ancestry.com.
How to use GEDmatch
Genetic Analysis: It is a third-party utility, not a testing company. You must download your "raw DNA data" from a site like AncestryDNA or 23andMe and upload it to GEDmatch. It provides advanced tools like chromosome browsers and "admixture" (ethnicity) calculators to analyze your segments in detail.
Genealogy Platform: While you can’t build a family tree directly on the site, you can upload GEDCOM files (family tree data) to see how your matches’ trees overlap with yours.
Cross-Database Matching: Its biggest advantage is allowing you to find relatives who tested with different companies (e.g., matching an Ancestry user with a 23andMe user).
Core Tools
| Tool | Purpose |
| One-to-Many | Lists all users in the database who share DNA with you. |
| One-to-One | Compares your DNA directly against a specific person to see exactly where you match. |
| Admixture | Provides various models to estimate your ethnic and regional origins. |
| GEDCOM Search | Searches family trees uploaded by other users to find common ancestors. |
Important Note
GEDmatch is widely known for its use by law enforcement to solve cold cases. When you upload, you can "opt-in" or "opt-out" of having your data visible for police searches.
Would you like me to walk you through how to download your raw data from a specific testing company
https://g.co/gemini/share/
PPPS
Mark, Tammie, Janie,If"Haplogroups are groups of individuals sharing common genetic mutations on either the Y chromosome (paternal haplogroups) or mitochondrial DNA (maternal haplogroups). These DNA regions are inherited without much recombination, making them useful for tracing deep ancestral lineages and human migration patterns. Women have both a maternal haplogroup from their mother and a paternal haplogroup that can be found by testing a father or brother..." ...I asked Gemini AI ABOUT MacLEOD genetics and haplogroups and promise or potential for future genetic genealogy testing and research and even extending or extreme longevity or aging reversal genetic research re MacLeods especially and got this helpful reply - https://g.co/gemini/share/b32c62516eb7. Mark - anything for Tammie in reaching out to males with the MacLeod last name at the 2nd day of the Pleasanton Highland Games besides - https://www.familytreedna.com/groups/acms-mac-leod/about ? ScottBlog post from yesterday Sat 8/30/25 about this and this thread in daily blog -On Sat, Aug 30, 2025 at 10:19 AM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote: Dear Tammie (Vawter, Mrs. California MacLeod), and Mark (MacLeod),Greetings, on the first day of the 152nd Caledonian Games (since 1866!) in the SF Bay Area, now in Pleasanton - https://thescottishgames.com/ - And I hope this email finds you well I won't be there at the Pleasanton Scottish Highland Games today or tomorrow ... but I just wanted to let you know about my 1st cousin Mark MacLeod's further research into MacLeod genetics; (He lives currently in Portland Maine, having lived in the SF Bay Area, and as a Stanford alum too - and who has given a genetic genealogy presentation at a MacLeod Parliament on Skye at least once, in 2023 I think ... Do you know each other by any chance?)Here's a fascinating and excellent paper on DNA of Clan MacLeod, significantly authored by Mark I think -The DNA of Clan MacLeod (2025)
By Mark K. MacLeod1, Colin Macleod and Roderick A. F. MacLeodhttps://archive.org/details/jo-gg-issue-131-mac-leod/page/ 1/mode/2up
WWW: Journal of Genetic GenealogyAnd here's his video for the MacLeod Parliament in 2023 -MacLeod, Mark K. 2023.
The DNA of Clan MacLeod: Is Leòd our common ancestor?
https://youtu.be/-5ZGWndVWNI
Isle of Skye, Scotland: https://www.youtube.com/@markkmacleod And his research on MacLeod genetics as haplogroups - "the paternal (Y-DNA) haplogroups of men with the MacLeod surname" - is coming up in Gemini AI conversational generative artificial intelligence searches, fascinatingly.AND Mark and MacLeod colleagues are seeking more men with MacLeod last names to take the Y-DNA MacLeod genetic test, here ...Tammie, please let MacLeods know about this MacLeod genetic genealogy ... :)(Seeking here to move forward with the MIT OCW-centric wiki World Univ & Sch WUaS Academic Medical Center, which is planning medical schools in all ~200 countries and in their main languages, including at Scotland WUaS - https://wiki.worlduniversityandschool.org/ wiki/Scotland from https://wiki. worlduniversityandschool.org/ wiki/Nation_States - into a newly safe vacant 670 Ridgecrest Rd Canyon CA 94516, with US federal law and state of California law working effectively together in new ways. Maybe see you next year, Tammie, and it would be great if this could occur with a family on the way:). Hold fast, (abolitionally), all the best, As Aye,ScottScott Gordon Kenneth MacLeod IIITwo Scottish small piping albums in the last few years -PSTammie Vawter Mrs MacLeod PacificPPPPPSWUaS GeneticsHow many professors, and researchers too, at WUaS eventually - & re 200 planned online med schools and teaching hospitals in 200 countries + ?genetics - how many professors does Harvard have?The Harvard Medical School Department of Genetics has 50 faculty members, with 39 holding tenured positions, according to the Harvard Genetics Department. This includes faculty from the Paul F. Glenn Center for Biology of Aging Research. Additionally, Harvard Medical School overall has "more than 11,000 faculty members" across its 15 hospital affiliates and research institutions, according to Harvard Medical Schools.On Sun, Jul 13, 2025 at 8:44 AM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote: Mark,Greetings and good morning on a Sunday. How are you doing?Still learning much about genetic genealogy including terms: and regarding specific genes' and haplogroups' language like R-BY3210 ... (and e.g. re a specific gene of aging reversal Harbard researcher Alex Plesa 's Twitter feed - https://x.com/amplesa/status/1737852952407326906 (with 8 impressive aging reversal Twitter posts with this ... and who is in George Church's lab at Harvard) - at the top by researcher Nathan Cheng in Spain -https://x.com/realNathanCheng/status/1938305010682761294 in the.PPPPS ... in a realistic virtual earth for genetics, for learning, and for aging reversal and extreme longevity too (by 2050 re "A Cure for Aging by 2050? - George Church " https://www.youtube.com/shorts/N6WdeclE__w ). With this as a possible model, start a MacLeod Y-DNA genetics' laboratory WITH a MIT OCW-centric World University and School genetics' laboratory, partly online to explore Leod and R-BY3210 and aging reversal and extreme longevity (in many many ways scientifically)? Further identity questions (I think), and per your research possibly too:HOW TO MEET and MARRY a MacLeod MD medical doctor, who might be 25-30 years old for example - (and in 25 Years be able to genetically age reverse to her mid 20s and be attractive) - to begin a family? UCSF's Donna Leet MD in the SF (Amherst and Harvard Med Sch alum from Seattle) who says online she's English but might have Scottish ancestry but also has also fairly recent African and possible 'wedgie' too ancestry and is attractive /pretty in pictures in the web, but whom I haven't yet met - and may be networked with HMS George Church too - who is also a professor of mine from this springs' INCREDIBLE MIT / Harvard HTGAA synthetic biology course (http://scott-macleod.blogspot.com/search/label/ HTGAA) ... and regarding MIT OCW-centric WUaS) and 35 ish (and who may know UCSF alums' & friend from Reed from 1979 Byron and Cindy Hann MDs in Canyon nearby Moraga)? A bit complex but what do you think, my genetic genealogist 1st cousin Mark, who is interested in propagating MacLeod genes - from your Friendly NtF NtQ Quaker and Yoga meditating cousin Scott ? Desiderata prose poem here ... and in my seeking to begin a family ... As a whistle blower and Friendly Quaker conscientious objector and in growing a WUaS worldwide abolition movement, and to abolish the wrongful buying and selling of people in the illegal sex, drugs, violence, car theft industries internationally and their latent networks if violence (so intl organized crime - and re Chase bank, trader joes, target along Penn Ave in Pgh), I haven't had an active credit card pretty much since March 1 2024 while in asylum in Pgh, so I can't yet do the Y-DNA MacLeod genetic test ...but thanks for letting me know about ... and how to integrate it in a useful realistic virtual earth for genealogy genetics as this develops? Thoughts? I also haven't yet moved into a newly safe vacant 670 Ridgecrest Rd Canyon 94516 which may lead to an active credit card too ...Regards, Hold fast, Happy Yoga genetics too, thanks,Scott"For #Olympics? #YogaGenetics? For performance - higher faster stronger athletics - & #ETHICS? What?" - more supple too (http://www.scottmacleod.com/yoganotations.html re previous quotes beginning with "For #Olympics? #YogaGenetics? ) ... and for muscle wasting reversal (so maybe regarding an initial focus on the genetics of 'height' questions per this fascinating George Church interview - A Billion Years of Evolution in a Single Afternoon — George Church PSWhat is R-BY3210 genetically? I asked Google AI and It interestingly responded with your 'identity' research -R-BY3210 is a Y-chromosome haplogroup within the larger R1b group, commonly found in Western Europe. It is specifically associated with the MacLeod clan, particularly its chiefly line, and is believed to represent a significant branch of the clan's founder's lineage. More precisely, it's a subclade of R-L165, which itself is a descendant of R1b.Here's a more detailed breakdown:
.This is one of the most common haplogroups in Western Europe, particularly in areas like the British Isles and Western Europe. .This is a specific branch of R1b, and the MacLeod chiefly line is known to carry this mutation. .This is a more recent subclade within R-L165, believed to be the founder lineage of the MacLeod clan. .The R-BY3210 haplogroup is strongly associated with the MacLeod clan, with a large portion of tested MacLeods belonging to this subgroup. .R-BY3210 is thought to represent the paternal line of the clan's founder, Leòd. .Within R-BY3210, there are further subclades or subgroups, indicating the clan's diverse genetic historPPSWhat is the R-BY3210 gene?The R-BY3210 gene: Understanding its role and significanceR-BY3210 is not a typical gene in the sense of encoding a protein with a specific function. Instead, it refers to a Y-DNA haplogroup, which represents a group of men who share a common paternal ancestor.Key aspects
- Y-chromosome marker: Haplogroups like R-BY3210 are identified by specific single nucleotide polymorphisms (SNPs), or variations in the DNA sequence, on the Y chromosome.
- Paternal lineage: The Y chromosome is passed down from father to son, largely unchanged, allowing geneticists to trace paternal lineages through generations.
- Founder lineage: R-BY3210 is believed to be the founder haplogroup for a significant portion of the MacLeod clan, suggesting their ancestors shared a common paternal line.
- Origin and expansion: The R-BY3210 paternal line branched off from the ancestor R-BY30488 around 850 CE and expanded into at least 2 descendant lineages (R-FTT137 and R-FTT138), according to FamilyTreeDNA Discover.
- Genealogy and history: Studying Y-DNA haplogroups like R-BY3210 helps researchers reconstruct the family tree of humankind and delve into the modern and ancient history of paternal surname lines.
In essenceR-BY3210 is a valuable tool for tracing paternal lineage and understanding human migration patterns through the analysis of Y-DNA haplogroups. It helps connect individuals to their ancestral roots and shed light on the historical movements and relationships of different populationsPPPS
Senator Warren, All, in what ways could @WorldUnivAndSch develop #WUaSMedSchs' #AvatarAgentElectronicHealthRec ords for these 17 million people without health care & for #TeleMedicine, AND #AgingReversal & #ExtremeLongevity #GeneResearch, & #WUaSGroceryStores for the 40 million?
https://x.com/WorldUnivAndSch/status/1944402201809723734
https://x.com/WUaSPress/status/1944404783814639963 ?
https://x.com/sgkmacleod/status/1944403657220596110 https://x.com/HarbinBook/status/1944407329379606603
https://x.com/scottmacleod/status/1944405162132648359
https://x.com/Q_YogaMacFlower/status/1944402921518743982
https://x.com/TheOpenBand/status/1944404629384827341
Retweeting -
Elizabeth Warren
@SenWarren
·
21h
Donald Trump's "Big Beautiful Bill" is now law.
It rips health care away from 17 MILLION people and raises grocery costs for 40 MILLION people, just to pay for tax handouts for billionaires and billionaire corporations.
Here's where we go next.
https://x.com/SenWarren/status/1944072930167861401 PPPPSNathan S. Cheng thinks you should work on aging.
@realNathanCheng
·
Jun 261/ LBF7 Spain is happening and we're doing something kinda wild:
-We’re gathering the smartest people who want to SOLVE AGING
-going to a longevity resort in the Spanish mountains
-to learn, discuss and ACTUALLY BUILD stuff for 7 days straight
Here’s what we’re cooking
https://x.com/realNathanCheng/status/1938305010682761294 PPPPSaLBF7 (lipopolysaccharide-binding protein) is not a gene directly associated with aging reversal based on the current search results. It is associated with inflammation and liver degeneration in aged mice, suggesting a possible role in the aging process rather than its reversal.However, it is important to note that
- Current aging research focuses on various approaches to potentially reverse or slow down aging, including genetic reprogramming and manipulating epigenetic information.
- These approaches aim to restore youthful functions and reverse age-related damage at the cellular level.
- For example, studies using gene therapy have shown promising results in reversing blindness and extending lifespan in mice and improving vision in monkeys.
Further research is needed to explore the potential of various genes and pathways in the context of aging reversalOn Fri, Jul 4, 2025 at 8:58 AM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote: Mark,Exploring these questions further here ... in yesterday's W 7/3/25 daily blog post -https://scott-macleod.blogspot.com/2025/06/white- throated-kingfisher-halcyon. html with some great Gemini conversational generative artificial intelligence AI Overview responses to some related genetics' questions. Asking further whether -Are #WholeGenomeSequencing #WGS & -#GeneticGenealogy AND -#ExtremeLongevity & #AgingReversal #GeneticDrugTherapies ahead -in a #RealisticVirtualEarthForGenomi cs #GenomesWUaS https://www. nature.com/articles/d41586- 021-01506-w? How could a # RealisticVirtualEarthForGeneti cs help? - https://scott-macleod. blogspot.com/2025/06/white- throated-kingfisher-halcyon. html ~
https://x.com/WorldUnivAndSch/status/1941159710973219226 with six further related Tweets.Found a Nature article too that suggests Y-Chromosome sequencing isn't yet complete -04 June 2021
A complete human genome sequence is close: how scientists filled in the gaps
Researchers added 200 million DNA base pairs and 115 protein-coding genes — but they’ve yet to entirely sequence the Y chromosome.
By Sara Reardon
https://www.nature.com/articles/d41586-021-01506-w Thoughts?ScottOn Thu, Jul 3, 2025 at 11:50 AM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote: Dear Mark,Thanks for this excellent video ... And can you say this in Scottish Gaelic or the Scots' language (with and without Google Translate for Youtube?:) -- and this time I took some notes and am asking some questions that come to mind ... and in learning the language of genetics (from a practical family identity biology perspective) - genealogy genetics - and in seeking to understand your thinking especially. (And how could we eventually represent the data and questions you cover in new ways in a realistic virtual earth for genealogy and genetics?). (Am recalling that all people share ~50% of their genetic material with each of their parents, 25% with their grandparents, and see PS ... And as I've mentioned to you before, I enjoy seeing 'who came before' in genealogy platforms online ... and learning about them with genealogy software / platforms / trees ... and regarding construing your questions possibly in a different way. And could I see your Ancestry .com family tree to go back from Norman John MacLeod to Leod in one way or another, and add some of this to https://www.wikitree.com/wiki/MacLeod-2524 ? ... And with Ancestry .com's new updated genetics' email, do I have to be a member to access this? And am curious further to learn how you're approaching analyzing MacLeod DNA data here too - https://www.familytreedna.com/ groups/acms-mac-leod/dna- results - and for the extreme longevity genetics' long term too ie if we live to 1500 years old ... with lots of MacLeod offspring further:) at the 1:45 minute marker -"Is Leòd really our common ancestor?"Are you asking can we extrapolate every MacLeod's genetics in the first group you identify - and I'd be interested to see the genetic data for this in another possible great MacLeod DNA video you make (i.e. with the last name MacLeod, and the genetics for those we don't have names, documents, or otherwise biographical or genealogy evidence for) - to trace them back to Leòd, as in he's the ~20th (or 25th or whatever the number) great grandfather of each and everyone with the last name MacLeod? And I wonder too if you're engaging in a form of scientism or social constructionism regarding here are the Clan Macleod family history narratives, construed by you as The DNA of Clan MacLeod, and here's a scientistic window into reading the genetics from a genealogy genetics perspective. What do you think? I found your talk very compelling and fascinating. Thanks you(my initial related question genetically somehow is - How are people all with the last name MacLeod in my and your genetic lines related, and how can we see this with current genealogy genetic tests - not yet whole genome sequencing - and how do we navigate the ancestors we have no biographical data for, but do have extrapolatable genetic data for?2:00"All of MacLeod men today can be placed into 1 of 5 distinct genetic groups ..."I'd be interested further in seeing some of this actual data perhaps at some point ... appreciating your broad introduction into genetics (with the practical lens of family genealogy and a quite coherent MacLeod DNA identify genetic narrative) ...How to make all the data you draw on accessible in an open source manner such that scientists and geneticists - and genetic genealogists - could further develop your great thinking - AND in a #RealisticVirtualEarthForGeneal ogy (https://x.com/scottmacleod/ status/1407796864662003716)? I'll have a look again atThe DNA of Clan MacLeod (2025)
By Mark K. MacLeod1, Colin Macleod and Roderick A. F. MacLeod
WWW: Journal of Genetic Genealogyin some of the above regards too.Mark - appreciating much your abstracting to MacLeod DNA family history in creative and chiefly ways ... as a great MacLeod historian as well ...Hold fast, warm regards, Happy birthday again,Scottblog post to come further and in this label too -PSIfall people share~50% of their genetic material with each of their parents25% with their grandparents12.5 % with great grandparents6.25 % with great great grandparents3.125 % with great great great grandparentshow much with each of the next 10 generations?Asked Gemini AI and found out -Here's how much genetic material is shared with each of the next 10 generations, continuing the halving pattern:
Great-great-great-great grandparents (1st next generation): 3.125%/2=1.5625%
Great-great-great-great-great grandparents (2nd next generation): 1.5625%/2=0.78125%
Great-great-great-great-great-great grandparents (3rd next generation): 0.78125%/2=0.390625%
Great-great-great-great-great-great-great grandparents (4th next generation): 0.390625%/2=0.1953125%
Great-great-great-great-great-great-great-great grandparents (5th next generation): 0.1953125%/2=0.09765625%
Great-great-great-great-great-great-great-great-great grandparents (6th next generation): 0.09765625%/2=0.048828125%
Great-great-great-great-great-great-great-great-great-great grandparents (7th next generation): 0.048828125%/2=0.0244140625%
Great-great-great-great-great-great-great-great-great-great- great grandparents (8th next generation): 0.0244140625%/2=0.01220703125%
Great-great-great-great-great-great-great-great-great-great- great-great grandparents (9th next generation): 0.01220703125%/2=0. 006103515625%
Great-great-great-great-great-great-great-great-great-great- great-great-great grandparents (10th next generation): 0.006103515625%/2=0. 0030517578125%
It's important to note that these percentages represent theoretical averages. Due to the random nature of genetic recombination, the actual amount of shared DNA with any specific ancestor can vary slightly.
https://g.co/gemini/share/f1a33fd1789c PPSall people share, so, MARK, can you fill in the names or genetic data proxies for those MacLeods prior to Norman James MacLeod ? ...~50% of their genetic material with each of their parents - (Gordon K MacLeod MD - https://www.wikitree.com/wiki/MacLeod-2525 - for me - https://www.wikitree.com/wiki/ MacLeod-2524, or Bruce Vincent MacLeod - https://www.wikitree.com/wiki/ MacLeod-2527 -for you - https://www.wikitree.com/ wiki/MacLeod-2532 ) 25% with their grandparents (Gordon K MacLeod Sr - https://www.wikitree.com/wiki/MacLeod-2528 ) 12.5 % with great grandparents (Ernest James MacLeod - https://www.wikitree.com/wiki/MacLeod-2924 ) 6.25 % with great great grandparents - James McLeod / MacLeod - https://www.wikitree.com/index.php?title=MacLeod-2925 (and just removed the 'Edward' per your research) - who emigrated from Scotland 3.125 % with great great great grandparents (Norman John MacLeod - https://www.wikitree.com/wiki/MacLeod-2926) 1.5625% with great-great-great-great grandparents (who is?)0.78125% with great-great-great-great-great grandparents0.390625% with great-great-great-great-great-great grandparents 0.1953125% with great-great-great-great-great-great-great grandparents 0.09765625% with Great-great-great-great-great-great-great-great grandparents 0.048828125% with Great-great-great-great-great-great-great-great-great grandparents 0.01220703125% with Great-great-great-great-great-great-great-great-great-great- great grandparents 0.006103515625% with Great-great-great-great-great-great-great-great-great-great- great-great grandparents PPPS
How best to dev #GenealogyResearchWU in a new direction in a #RealisticVirtualEarth, #RealisticVirtualEarthForGeneal ogy, # RealisticVirtualEarthForHistor y, a # RealisticVirtualEarthForGeneti cs & re #AgingReversalGenetics & #ExtremeLongevityGenetics, w related #GeneTherapies coming?
https://x.com/scottmacleod/status/1924253472939258284
https://x.com/WorldUnivAndSch/status/1924253052036682162
https://x.com/Q_YogaMacFlower/status/1924253576752517185
https://x.com/HarbinBook/status/1924254393630888430
https://x.com/sgkmacleod/status/1924253883142156636
https://x.com/WUaSPress/status/1924254076398875123
Retweeting -
Roots in #VintonIA #DesMoinesIA How could I #ScottGKMacLeod talk virtually with my mother's Pa #SandyBrown #AlexanderChadbourneBrown & #ChadbourneAncestors #wuAsVR #WUaSAR? #REALISTICVIRTUALEARTHFORHISTOR Y in #GoogleStreetView w #TimeSlider & for # REALISTICVIRTUALEARTHForGeneal ogy?
https://x.com/scottmacleod/status/1407796864662003716
AND
https://x.com/TheOpenBand/status/1924254804462928365
retweeting Clan MacLeod parliament
#ClanMacLeod Parliament is in full swing now with over 300 delegates attending the week's full programme of events. The pic shows the first Clan Parliament in 1956. The gathering of MacLeods from all over the globe was an idea of Dame Flora MacLeod, the 28th Chief of the Clan.
https://x.com/Dunvegan_Castle/status/1021747928598306816 PPPPSHow is whole genome sequencing of ancestors in genealogy done, if at all?Whole genome sequencing (WGS) in genealogy involves analyzing an individual's entire DNA sequence to understand their ancestry and potentially identify relatives, though it's not the primary tool used in most consumer-grade genealogy testing. While traditional genealogy relies on autosomal DNA, WGS offers a more comprehensive view of the genome, including non-coding regions and rare variants, which can be valuable for tracing deep ancestry and identifying distant relatives.Here's how it works and its role in genealogy:1. DNA Extraction and Sequencing:
- A DNA sample (usually blood or saliva) is taken from an individual.
- The DNA is extracted, purified, and then sequenced using specialized machines that read the order of all base pairs (A, T, C, and G) in the genome.
- This process, known as whole genome shotgun sequencing, breaks the DNA into smaller fragments, sequences them, and then reassembles them to create a complete DNA sequence.
2. Data Analysis and Interpretation:
- The raw DNA data is then analyzed using bioinformatics pipelines to identify genetic variants and compare them to reference genomes.
- This analysis can reveal information about ancestry, including ethnic origins and potential connections to other individuals who have also been sequenced.
- While WGS can be used for traditional genealogical research, it's more commonly used in genetic genealogy to identify distant relatives, uncover deeper ancestral lineages, and solve cold cases where traditional methods have failed.
3. WGS vs. Other DNA Tests:
.(like those offered by 23andMe, AncestryDNA, and MyHeritage) typically analyze specific regions of the genome (like SNPs) to estimate ethnicity and identify close relatives. 4. WGS in Genetic Genealogy:
- WGS can be valuable for identifying distant relatives by analyzing shared DNA segments, even those that are small and rare.
- It can be used to break through "brick walls" in family trees by identifying previously unknown connections and tracing lineages back further in time.
- WGS data can be used in conjunction with traditional genealogy methods to build more complete and accurate family trees.
5. Challenges and Considerations:
- Cost: WGS is significantly more expensive than other DNA tests.
- Data Storage and Interpretation: WGS generates a large amount of data that requires specialized expertise for analysis and interpretation.
- Privacy: WGS data can reveal sensitive information about health and ancestry, so it's crucial to consider privacy and data security.
In conclusion, while WGS is not the primary tool used in most genealogy testing, it offers a powerful approach for understanding deep ancestry and identifying distant relatives due to its comprehensive analysis of the genomePPPPSJulia Abernethy ucl macleod genetic study linkedin12:30 in videoOn Thu, May 22, 2025 at 5:53 PM Scott MacLeod <sgkmacleod@worlduniversityandschool.org> wrote: Mark,In a related vein, I just shared this with you and my mother, Jane, Sid/Pin (Mazumdar in HHS in the US federal govt & best friend from high school), and best friend in the SF Bay Area Ed (Smyth MD) -"Hi Ed, Ma, Pin, ... How are you? Greetings! Thanks Ed for precipitating my moving into a newly safe 670 Ridgecrest Road, and with WUaS PO Box 442, Canyon 94516 mail too ... and I can hypothesize that the investigation into the culture of criminality and international organized crime in the greater SF Bay Area, and individuals too, back decades even ... may be unfolding further since I first drove west from asylum in Pgh on 12/10/24 ... Just emailed my cousin Mark Macleod in Portland Maine further (and as a Stanford alum, and possibly a US general re the Oil industry per LinkedIn, and having lived in Scotland too and being deeply interested in genealogy genetic) ... re my ongoing seeking to move into a newly safe Canyon 94516 ... and beginning a family -
"Scott MacLeod <sgkmacleod@worlduniversityandschool.org>
4:08 PM (39 minutes ago)
to MacLeod
Hi Mark,
Appreciating the genetic genealogy language in your paper ...
The DNA of Clan MacLeod (2025)
By Mark K. MacLeod, Colin Macleod and Roderick A. F. MacLeod
WWW: Journal of Genetic Genealogy
https://archive.org/details/jo-gg-issue-131-mac-leod
and the name Dave Vance also came up in its regard (with a Brown University degree in CS from 1984) ...
https://blog.familytreedna.com/dave-vance-named- familytreedna-general-manager/
https://www.linkedin.com/in/jdavidvance
Will read your paper further ... and re #TextInTheSidebar of a #RealisticVirtualEarthForGeneal ogy # RealisticVirtualEarthForGeneti cs ... and could Dave Vance and Rob Spencer even help with this, potentially with Peter Norvig and Google too?
And how to connect potentially with Donna Leet MD I wonder? (And might we move in together to a newly safe open 670 Ridgecrest Rd, Canyon 94516, where I lived for about 13 years until calling the local police twice at Stanford alum too Cindy, and Byron, Hann MDs encouragement {who lived together in Scotland for 3 years, and where Byron's step-brother may be stationed in Scotland as part of the US federal government even} from nearby Moraga CA)?
Regards, Hold Fast MacLeod, best wishes,
Scott
https://scott-macleod.blogspot.com/2025/05/hawaiian- monk-seal.html
PS
WUaS is just making contact with Rippling in SF and the US federal government and state of CA too ... regarding next steps forward -
https://scott-macleod.blogspot.com/2025/05/butte- county-meadowfoam.html ...
Scott" Thoughts?Fond regards, abolition-ally, Harbin ethnographically, Yogically,Scott (Thoughts, Mark?Hold Fast MacLeod, best wishes, Happy birthday further!,ScottSociety, Information Technology, and the Global University (2025, forthcoming)Scottish Small Piping album #2 - Honey Piobaireachd (2022)- https://twitter.com/TheOpenBand (Berkeley) Scottish Small Piping album #1 Honey in the Bag ~ Out of the Air tune (2020)Order Book #4 To the Dance or the Pools? ~ Virtually! How different it is to soak at Harbin Hot Springs, than to realize it in virtual reality (2019)Order Book #3 Winding Road Rainbow: Harbin, Wandering & the Poetry of Loving Bliss (2018)Order Book #2 Haiku-ish and Other Loving Hippie Harbin Poetry (2017)Order Actual-Virtual Ethnographic Book #1: Naked Harbin Ethnography (2016)- Scott GK MacLeodFounder, President, CEO & ProfessorCC-4 licensed MIT OCW-centric, Wiki,World University & School (WUaS)- USPS US Post Office, General Delivery, Canyon, CA 945161) non-profit 501(c)(3) Public CharityMIT OCW-centric,World University and School - http://worlduniversityandschool.org 2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/ AcademicPress.html (o) 415 480 4577 - sgkmacleod@worlduniversityandschool.org (m) 412 478 0116 - sgkmacleod@gmail.comWorld Univ & Sch Innovation Research - scottmacleod.com
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https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
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Wednesday, March 8, 2023
Purple sunbird: Stanford Mine Pi - WUaS Corporation Partnership Proposal * (Stanford Mine Pi - "slight of coding"?)
Stanford Mine Pi - WUaS Corporation Partnership Proposal * (Stanford Mine Pi - "slight of coding"?)
https://
https://scott-macleod.
Wednesday, March 8, 2023
Purple sunbird: Stanford Mine Pi - WUaS Corporation Partnership Proposal * (Stanford Mine Pi - "slight of coding"?)
Stanford Mine Pi - WUaS Corporation Partnership Proposal * (Stanford Mine Pi - "slight of coding"?)
https://
https://scott-macleod.
Your reference is PINETWORK-778183. Check sgkmacleod@
Click on a category below to send us an email
Partnership/Vendor Proposals
Please use this form if you wish to offer your service or collaborate with Pi Network. If you are a developer looking to develop an app on the Pi ecosystem, please submit your request on our Developers/Pi Apps Platform form.
Email confirmation to*
Summary*
Yes
Do you have any suggestions for improving the clarity and structure of the roadmap?
Looks great, - yet with the WUaS Corporation / MIT OCW-centric wiki World University and School having received a partnering email from the Pi Network organization in March of 2023 - https://scott-macleod.
What other specific historical information would you have liked to see? Please specify which part of the Roadmap you are commenting on.
As you may or may not know, and in the WUaS Corporation / MIT OCW-centric wiki World University and School partnering with the Pi Network, WUaS seeks to code for all 7.9 billion people on the planet, in all ~200 countries, and in their main languages, from here - https://wiki.
What additional information would you like to see in the 'In Progress' section? Please specify which part of the Roadmap you are commenting on.
How could the Pi Network organization extend this to all 200 countries' main languages, or to speakers even of all 7, 168 known living languages - "Released translation mechanism to enable Pi Chat Moderator community to help translate the UI text in the Pi Mining app in 50 languages; later extended to Pi KYC and Fireside Forum apps" ?
What specific elements would you like to see elaborated in Version 2 concerning upcoming features, requirements, upgrades, and initiatives needed before entering the Open Network period?
(Possibly something about - a video? - how and when some Pioneers will actually be able to buy or sell something with Pi on the MainNet blockchain when this eventually happens? ... eg an example, or an instance?)
Do you have any specific suggestions on how we can better present the comprehensive plans for Pi Network's Enclosed Network period leading into the Open Network period?
Looks really great
Any other comments or suggestions?
How best, please, besides such forms, and on Twitter - https://twitter.com/
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric. Wiki,
World University & School (WUaS)
- PO Box 442, Canyon, CA 94516
- 210 East End Avenue, Pittsburgh, PA 15221
- 5816 Callowhill St. Pgh PA 15206
1) non-profit World University and School - http://
2) for profit general stock company WUaS Corporation in CA - http://
(o) 415 480 4577 - sgkmacleod@
(m) 412 478 0116 - sgkmacleod@gmail.com
World Univ & Sch Innovation Research - scottmacleod.com )
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https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/TheOpenBand/
Searched on
abolition of wrongful buying and selling of people - so modern slavery - at #wikiWUaS @WorldUnivAndSch building on #MITOCW in ~7 languages & wikidata wikipedia in ~342 langs
https://
-https://scott-macleod.
https://share.google/aimode/
*
- Academic Study: MIT coursework, such as Slavery and Human Trafficking in the 21st Century, examines the, economic, and social underpinnings of modern servitude, including labor trafficking, debt bondage, and sexual exploitation.
- Research & History: Research initiatives (e.g., "MIT and Slavery") explore the historical connections between the institution's founders and the slave economy, fostering understanding of how such structures persist.
- Active Advocacy: The MIT Program on Human Rights and Justice has hosted symposiums in partnership with the BBC World Service Trust to highlight the role of forced labor in the global economy and promote solutions.
- Modern Day Focus: Modern slavery is defined by illegal control rather than legal ownership, spanning forced prostitution, child soldiering, and trafficking, which are analyzed for potential policy and technological interventions.
- Actionable Solutions: Strategies focus on the "4 P's" (Prevent, Pursue, Protect, Prepare), including supply chain transparency, ethical consumerism, and supporting abolitionist movements.
*
https://gobotany.nativeplanttrust.org/species/daucus/carota/
https://wildadirondacks.org/adirondack-wildflowers-queen-annes-lace-daucus-carota.html
https://en.wikipedia.org/wiki/Daucus_carota
https://commons.wikimedia.org/wiki/Daucus_carota
https://en.wikipedia.org/wiki/Daucus
...
1/ LBF7 Spain is happening and we're doing something kinda wild: