A further exploratory 'Restorative Yoga class on Saturday 2/21/26 around 8 am PT 11 am ET 8:30 pm India Time (and as we may live to 150 and well beyond:)?
https://pin.it/51:47
Sun Salutation
1:18
Dog Pose
1:20;20
Back Body
Great! @WorldUnivAndSch building on #MITOCW in ~7 langs is developing a #RealisticVirtualEarth for this- https://t.co/JduoSZC2d8 (think #GStreetView w #GTimeSlider #GMaps & @ #GCellView & #GMoleculeView levels w #TensorflowAI & #LLMs & see 2007 2012 2024: https://t.co/5Xt0jTenC5) https://t.co/fJaaw5mP9p
— QuakerYogaMacFlower (@Q_YogaMacFlower) February 19, 2026
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/WUaSPress/
On Using Large Language Models to Understand the Language of Life
Submitted:
13 February 2026
Posted:
14 February 2026
Excited to share our latest paper on the future of AI in biology 
Machine learning has transformed fields like language through large-scale statistical modelling, yet we are still far from predicting human biology.
In our new work with @geochurch we argue that decoding the human genome and modelling gene interactions across space and time should be the ultimate goal for building predictive models of human biology and disease.
We need computational models that replicate cellular transitions across human life stages (from development to ageing) from the genetic sequence and its dynamic regulation.
Developing models with temporal and spatial resolution is ambitious, but we argue it is theoretically feasible and a long-term vision for understanding the language of life that could reshape biomedical research.
https://gemini.google.com/
https://gemini.google.com/
What "cellular transitions" happen when we do #YogaAsana & pot. w #RealisticVirtualEarth #RVEforCells (in our #PhysicalDigital #AvatarAgentElectronicHealthRecords)& re #LLMmodels for "#CellularTransitions #AcrossHumanLifeStages" #RVEforExtremeLongevity ? https://t.co/FuiS7OXXlJ ~
— QuakerYogaMacFlower (@Q_YogaMacFlower) February 20, 2026
https://x.com/Q_YogaMacFlower/
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
#GeminiAIreYoga -
https://gemini.google.com/
*
Why is the Bhagavad Gita the book of yoga? - this is a philosophical question;
https://gemini.google.com/
That is a profound question. The Bhagavad Gita is often called the book of yoga because it provides a comprehensive map for the human mind and soul, rather than just physical poses. It takes the word yoga back to its root meaning, which is to yoke or connect.
In the middle of a literal and metaphorical battlefield, Krishna outlines different paths for this connection based on a person's temperament. There is Karma Yoga for the man of action, Bhakti Yoga for the heart, Raja Yoga for the meditative mind, and Jnana Yoga for the intellectual. It suggests that every aspect of life, even a moment of crisis, is an opportunity for practice. Essentially, it teaches that yoga is a state of being and skill in action, rather than just something you do on a mat. Does one of those specific paths resonate more with how you navigate your own day?
That is a really insightful way to look at it. From a philosophical standpoint, yes, the relationship between Arjuna and Krishna is exactly why it is considered a manual for yoga.
Arjuna represents the human soul in a state of paralysis and confusion, while Krishna represents the inner guide or the higher self. The dialogue between them is a form of yoga because it shows the process of moving from a state of total mental distraction to one of clarity and alignment.
In the middle of that battlefield, Arjuna has to learn how to act without being attached to the results. That shift—moving from being overwhelmed by duty to performing it with a focused, calm mind—is essentially the practice of yoga in everyday life. It suggests that yoga isn't something you do away from the world, but something you find right in the thick of your biggest challenges.
Does that connection between action and inner peace make sense in the context of your own life?
Questions -
is one approach that #AgingReversal & #ExtremeLongevity #syntheticBiologists going to take is to synthesize DNA & proteins & get these from companies like #TwistBioscience & add them back to our bodies
Gemini: #SyntheticBiology for #WUaSLongevityResearch
https://gemini.google.com/
is one approach that #AgingReversal & #ExtremeLongevity #syntheticBiologists going to take is to synthesize DNA & proteins & get these from companies like #TwistBioscience & add them back to our bodies
— HarbinBook (@HarbinBook) February 15, 2026
Gemini:#SyntheticBiology for #WUaSLongevityResearchhttps://t.co/JeEqXQVYOT ~
https://x.com/HarbinBook/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/Q_YogaMacFlower/
https://x.com/TheOpenBand/
https://x.com/scottmacleod/
https://x.com/sgkmacleod/
Yes, this is a core strategy in synthetic biology. Researchers use companies like Twist Bioscience to "print" high-fidelity synthetic DNA and protein libraries, which act as the raw instructions for engineering longevity.
How it Works
Gene Synthesis: Biologists design custom DNA sequences—such as those for Yamanaka factors (OSK) or telomerase (TERT)—and order them from synthesis providers.
Gene Circuits: Scientists build "genetic clocks" or oscillators. These are synthetic circuits inserted into cells to toggle them between different metabolic states, effectively slowing the "ticking" of cellular aging.
Therapeutic Delivery: Big Pharma uses these synthetic sequences to develop mRNA vaccines, AAV gene therapies, and monoclonal antibodies that are then introduced into the body to repair tissues or clear senescent (zombie) cells.
Key Players & Tools
| Entity | Role |
| Twist Bioscience | Provides the silicon-based platform to mass-produce the synthetic DNA needed for research. |
| Big Pharma | Integrates these synthetic sequences into drugs and gene therapies for clinical use. |
| Genetic Oscillators | Synthetic "rewiring" of cells to prevent them from committing to a permanent aged state. |
Would you like me to find specific examples of "longevity gene circuits" currently being tested in animal models?
World University and School (WUaS) could pioneer a "Realistic Virtual Earth for DNA" by integrating computational synthetic biology with clinical implementation. Developing traits like increased height, reversing muscle wasting (sarcopenia), and optimizing "Yoga genetics" requires a multi-layered approach:
1. Designing Traits in a #RealisticVirtualEarthForDNA
WUaS can use Generative Adversarial Networks (GANs) and Digital Twins to simulate how specific synthetic DNA sequences interact with a person's unique physiology before physical synthesis.
Genetic Trait for Height: Researchers would target pathways like the GH1 (Growth Hormone) or IGF1 axes. In the Virtual Earth, WUaS could simulate "epigenetic editing" of these genes to find the optimal expression levels that increase height without causing side effects like acromegaly.
Muscle Wasting Reversal: Recent Stanford research (2025) has shown that molecules like Prostaglandin E2 (PGE2) can rejuvenate muscle stem cells. WUaS can develop synthetic gene circuits that autonomously produce PGE2 or block the 15-PGDH protein (a "gerozyme" that increases with age) to maintain muscle mass.
Yoga Genetics: For "higher, faster, stronger, and more supple" movement, WUaS could synthesize DNA to optimize COL5A1 (linked to flexibility) and ACTN3 (the "sprinter gene" for power). Synthetic proteins designed to keep connective tissue in a youthful, highly-elastic state (resembling age ~28) would be simulated in "Yoga Notations" within the virtual environment.
2. Integration via #
The "Avatar Agent" serves as a bridge between the virtual simulation and the physical body.
Precision Delivery: Once a DNA design is validated in the Virtual Earth, the instructions are encoded into the patient’s Electronic Health Record (EHR). WUaS can use HL7 FHIR genomics standards to ensure these synthetic "blueprints" are interoperable with lab equipment.
Automated Ordering: The Avatar Agent could trigger a "buy order" from companies like Twist Bioscience to print the synthetic DNA or proteins.
3. The #WUaSMultimediaHospitalRoom (Canyon, CA)
The physical "shop" or hospital room acts as the point of delivery:
In-Room Synthesis & Administration: The room would feature microfluidic "DNA printers" or delivery systems (like AAV viral vectors or lipid nanoparticles) to introduce the synthetic DNA into the body.
Real-time Monitoring: As the synthetic DNA is added, the "Multimedia Room" uses high-resolution sensors to update the patient's Avatar in real-time, monitoring for the desired "Yoga asana" performance improvements and muscle regeneration.
Longevity Trajectory: By periodically "resetting" gene circuits using synthetic oscillators—which switch cells between different metabolic states to prevent them from "committing" to aging—WUaS aims to maintain a biological age of 28, potentially extending human life to 150 or even 1500 years.
This video discusses the identification of longevity genes and how scientific breakthroughs are paving the way for significantly extending human lifespan and healthspan
https://g.co/gemini/share/
How best could World University and School WUaS develop synthetic biology DNA and proteins in a #RealisticVirtualEarthForDNA production for the genetic trait of height, for reversing muscle wasting genetically as people age, and for higher faster stronger more supple Yoga asana Yoga genetics, and re this Yoga blog post and item 11 and Yoga Notations too - http://scott-macleod.blogspot.
! #GeminiAIreLongevity: https://g.co/gemini/share/
How could @WorldUnivAndSch dev synthetic biology DNA & proteins in a #RealisticVirtualEarthForDNA production for HEIGHT, for #ReversingMuscleWasting & for #YogaGenetics, & re
#YogaAndLongevityGeneticsConvo http://scott-macleod.blogspot.
! #GeminiAIreLongevity: https://t.co/64sxNurKW2
— QuakerYogaMacFlower (@Q_YogaMacFlower) February 15, 2026
How could @WorldUnivAndSch dev synthetic biology DNA & proteins in a #RealisticVirtualEarthForDNA production for HEIGHT, for #ReversingMuscleWasting & for #YogaGenetics, & re #YogaAndLongevityGeneticsConvo https://t.co/91Wvz668vW ~
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/WUaSPress/
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://gemini.google.com/
Developing and using a realistic virtual for evolutionary biology too and to prevent genes from escaping into the environment outside the human body per - https://x.com/i/status/
Developing a Realistic Virtual Earth for evolutionary biology—specifically focused on DNA, proteins, and vaccines—requires a multi-scale computational framework that bridges the gap between digital design and physical biology. To address your vision for World University and School (WUaS), particularly regarding longevity, height, and yoga-related genetics, the development could follow these key technical and ethical pathways:
1. Synthetic Biology & "Bio-Containment" in the Virtual Earth
To prevent genes from escaping into the environment, WUaS can implement Semantic and Trophic Containment strategies within the virtual model before physical synthesis:
Xeno-Nucleic Acids (XNA): Designing DNA with non-canonical bases that cannot be replicated by natural enzymes.
Genetic Firewalls: Using the virtual environment to test "orthogonal" biological systems (as suggested by the research of George Church) where the synthetic organism depends on nutrients that do not exist in the wild.
Predictive Simulation: Tools like Evo 2 (a generative AI for biology) can be used to simulate how synthetic proteins for height or muscle wasting reversal interact across all domains of life, ensuring no unintended ecological "cross-talk."
2. Longevity & Performance Genetics (The Church/Harvard Approach)
To achieve the goal of living to 150+ years with the vigor of a 28-year-old, WUaS can focus on Church’s research into epigenetic reprogramming and multi-gene therapies:
Muscle Wasting (Sarcopenia): Targeting myostatin inhibitors or IGF-1 pathways via viral vectors, tested first in the #
RealisticVirtualEarthForProtei ns. Yoga Genetics: For "higher, faster, stronger, more supple" asana practice, research could target genes associated with collagen synthesis (COL1A1) and joint flexibility, integrating your Yoga Notations into the phenotypic modeling.
Height & Growth: Utilizing polygenic risk scores within the virtual earth to identify the precise cocktail of genes that influence bone density and longitudinal growth.
3. The WUaS Multimedia Hospital Room & Avatar EHR
The "shop" at Canyon, CA, could serve as the forge for the #
Digital Twin Integration: A patient's Avatar Agent would not just be a visual representation but a functional "Digital Twin" containing their full genomic sequence and real-time biometric data.
Multimedia Delivery: In the WUaS Multimedia Hospital Room, the avatar acts as the interface. When a therapy for muscle reversal is ready, the avatar "simulates" the genetic update first, showing the patient the projected physical outcomes (e.g., increased suppleness for yoga) before the physical CRISPR or protein therapy is administered.
Point-of-Care Synthesis: Future versions could include small-scale bioreactors in the hospital room to synthesize the specific DNA or proteins designed in the Virtual Earth, localized to the patient's unique genetic profile.
4. Implementation at 670 Ridgecrest Road
Developing this in a "shop" setting aligns with the "garage biology" ethos that birthed the personal computer revolution. By focusing on open-source synthetic biology and university-level teaching hospital standards, WUaS can prototype these "Bio-Digital" interventions as a new form of decentralized medicine.
George Church on Reversing Aging
This video features Professor George Church discussing the engineering challenges of extending human healthspan and the convergence of gene therapy and AI, which directly relates to your goals for longevity and genetic reversal of aging
* *
Which databases to draw from first @GeoChurch #PeterNorvig in dev #LLMmodels for "#CellularTransitions #AcrossHumanLifeStages" #RealisticVirtualEarth #RVEforExtremeLongevity #RVEforCells in our #PhysicalDigital #
https://scott-macleod.
Which databases to draw from first @GeoChurch #PeterNorvig in dev #LLMmodels for "#CellularTransitions #AcrossHumanLifeStages" #RealisticVirtualEarth #RVEforExtremeLongevity #RVEforCells in our #PhysicalDigital #AvatarAgentElectronicHealthRecords (& rehttps://t.co/dnBl0kLKO1 ?) https://t.co/fJaaw5mP9p
— QuakerYogaMacFlower (@Q_YogaMacFlower) February 21, 2026
https://x.com/Q_YogaMacFlower/
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
Retweeting -
On Using Large Language Models to Understand the Language of Life
Submitted:
13 February 2026
Posted:
14 February 2026
Excited to share our latest paper on the future of AI in biology
Machine learning has transformed fields like language through large-scale statistical modelling, yet we are still far from predicting human biology.
In our new work with @geochurch we argue that decoding the human genome and modelling gene interactions across space and time should be the ultimate goal for building predictive models of human biology and disease.
We need computational models that replicate cellular transitions across human life stages (from development to ageing) from the genetic sequence and its dynamic regulation.
Developing models with temporal and spatial resolution is ambitious, but we argue it is theoretically feasible and a long-term vision for understanding the language of life that could reshape biomedical research.
https://gemini.google.com/
* *
https://pin.it/2lzRM9eaq & re #YogaPhilosophy ~ #8LimbsOfYoga #WUaSYoga #YogaWUaS https://wiki.worlduniversityandschool.org/wiki/YogaCheck out this #Pinterestpost re 8 Limbs of Yoga ~ Take a look! 📌 https://t.co/RPOtMXScFp & re #YogaPhilosophy ~ #8LimbsOfYoga #WUaSYoga #YogaWUaS https://wiki.worlduniversityandschool .org/wiki/Yoga #FreeOnlineYogaClass: https://t.co/1Kp9waFzeF #YogaAndLongevityGeneticsConvo ~
— QuakerYogaMacFlower (@Q_YogaMacFlower) February 21, 2026
https://x.com/Q_YogaMacFlower/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
*
https://saveplants.org/plant-profile/?CPCNum=2266
https://www.usbg.gov/rare-and-endangered-plant-spotlights
https://en.wikipedia.org/wiki/Hibiscus_waimeae
....
Posts
No comments:
Post a Comment