Monday, November 18, 2024

Honey locust tree (Gleditsia triacanthos): M 11/18/24 open @WorldUnivAndSch #WUaSNewsAndQA #GrowWithGoogle #RealisticVirtualEarth #DeExtinction #RealisticVirtualEarthForGenetics ~ #freeToStudents' online #freeWUaSdegrees #freeToStudents' online - Bachelor, PhD, Law, MD, AA, Master's + * (was - M 11/18/24 World Univ & Sch WUaS News and Q&A, with Zoom URL)

 


M 11/18/24 open @WorldUnivAndSch #WUaSNewsAndQA #GrowWithGoogle #RealisticVirtualEarth #DeExtinction






M 11/18/24 open @WorldUnivAndSch #WUaSNewsAndQA #GrowWithGoogle #RealisticVirtualEarth #DeExtinction #RealisticVirtualEarthForGenetics ~
#freeToStudents' online #freeWUaSdegrees 
#freeToStudents' online - Bachelor, PhD, Law, MD, AA, Master's + 


M 11/18/24 open @WorldUnivAndSch #WUaSNewsAndQA #GrowWithGoogle #RealisticVirtualEarth #DeExtinction
https://youtu.be/il-DQN4ezoU
https://www.youtube.com/@ScottMacLeodWorldUniversity/videos
-https://scott-macleod.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos.html
https://worlduniversityandschool.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos-m.html #RealisticVirtualEarthForGenetics ~
#freeToStudents' online #freeWUaSdegrees ~

https://x.com/WorldUnivAndSch/status/1858553076241912270

https://x.com/Q_YogaMacFlower/status/1858553270396219488

https://x.com/scottmacleod/status/1858553206353416397


video pic 






#freeToStudents' online #freeWUaSdegrees - Bachelor, PhD, Law, MD, AA, Master's +




* * * 
M 11/18/24 next Welcoming open @WorldUnivAndSch -#WUaSNewsAndQA meets at 7am PT 10am ET w Zoom URL: https://worlduniversityandschool.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos-m.html -https://scott-macleod.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos.html {& see #MITOCW-centric wiki #WUaSUnivs' Sat 11/16/24 #WUaSMBM #GrowWithGoogle -https://youtu.be/uoG9ugz1ukw} >https://youtube.com/@ScottMacLeodWorldUniversity/videos ~

https://x.com/WorldUnivAndSch/status/1858500681528668353

https://x.com/scottmacleod/status/1858502141716935124









*

M 11/18/24 next Welcoming open @WorldUnivAndSch -#WUaSNewsAndQA meets at 7am PT 10am ET w Zoom URL: https://worlduniversityandschool.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos-m.html -https://scott-macleod.blogspot.com/2024/11/honey-locust-gleditsia-triacanthos.html {& see too #MITOCW-centric wiki #WUaSUnivs' Sat 11/16/24 #WUaSMBM #GrowWithGoogle -https://youtu.be/uoG9ugz1ukw} >https://youtube.com/@ScottMacLeodWorldUniversity/videos ~

https://x.com/scottmacleod/status/1858500047383474471

https://x.com/Q_YogaMacFlower/status/1858500148935958532

https://x.com/WorldUnivAndSch/status/1858499935219380409





Dear Universitians, 


Greetings with an invitation to join the MIT OCW-centric wiki World Univ & Sch WUaS Press M 11/18/24 World Univ & Sch WUaS News and Q&A in about 10 1/2 hours here - 




Topic: M 11/18/24 World Univ & Sch WUaS News and Q&A, with Zoom URL
Time: Nov 18, 2024 07:00 AM Pacific Time (US and Canada)

Join Zoom Meeting
https://us04web.zoom.us/j/72892539717?pwd=IeIq4boNxb9UCBlbDKp0XPoUFubPAT.1

Meeting ID: 728 9253 9717
Passcode: VLVFM5


Check out the WUaS Monthly Business Meeting from Saturday here - 

Sat 11/16/24 open MIT OCW-centric wiki @WorldUnivAndSch #WUaSMonthlyBusinessMeeting #GrowWithGoogle

https://youtu.be/uoG9ugz1ukw

https://www.youtube.com/@ScottMacLeodWorldUniversity/videos







- some of which and more, depending on who joins the call,  we'll examine further in the M 11/18/24 WUaS News and Q&A.

All the best, abolitionally, see you soon, 
Scott





*. *

Universitians, 

Agenda item 1 

World Univ & Sch is proceeding as 1) a nonprofit 501 c3 tax exempt MIT OCW-centric wiki set of 200 major online Universities, and with wiki schools in 7164 known living languages; 

And as 2) a for profit general stock company in the state of CA as legal entity for WUaS Educational Services' Stores, Academic Press at WUaS is 7164 known living languages with machine and human translation, and potentially with Stanford Mine Pi Cryptocurrency, also in ~200 countries and in their main languages

both with WUaS seeking to code for all 7.9 billion people on the planet, and to create free universal education, highest quality in the home, and potentially to end poverty worldwide too. 



1 a

1 b

Could friend Steve Cambor, SSA alumnus too, become the CEO of the WUaS Corporation ?





Agenda item 2

In a realistic virtual earth for genetics at WUaS ... 

De-extinction of the wooly mammoth, and other species eventually ... and de-extinction of even individuals 


consciousness (subjective experience) and memory 






2 a


#Deextinct the #WoolyMammoth virtually too @geochurch? In an emerging #WUaSMultimediaBarn in Canyon 94516? and even individuals too ? 

Re - 

#Deextinct #WoolyMammoth virtually too @geochurch in emerging #WUaSMultimediaBarn in #Canyon94516 & think #GStreetView w #TimeSlider #GMaps #GEarth #TensorFlowAI with #AppleVisionPro #DigitalMask -https://www.theage.com.au/technology/finally-a-new-apple-device-really-worth-talking-about-20240204-p5f286.html A #DigitalPhysicalGenome & add to
https://newrepublic.com/article/169528/woolly-mammoth-alaska-colossal-thiel ?

https://twitter.com/WorldUnivAndSch/status/1768669424016302238

https://twitter.com/scottmacleod/status/1768669571223834692






Vision pro pic ?



2 b

(see in a related way - 

george church
@geochurch
Oct 1
pictures of gene protuberances - 
https://x.com/geochurch/status/1841183460335276061

and - 
Colossal Biosciences Launches $50 Million Foundation To Halt Extinction Crisis
Who ever said you can't save a few species on the way to de-extincting a mammoth?

https://www.iflscience.com/colossal-biosciences-launches-50-million-foundation-to-halt-extinction-crisis-76180 )



2 c
Again 


Genetics of Protuberances? #GeminiAIOnGenetics
Asked: How do genetics or genomics create #GeneProtuberances such as fins or Mammoth tusks or Mammoth trunk or bird beaks?
https://g.co/gemini/share/2284bd7c4708
What to add @geochurch & re de-extinction & even #AgingReversal #ExtremeLongevity - https://scott-macleod.blogspot.com/2024/12/lobelia-species.html & from #GWASdata?

https://x.com/WorldUnivAndSch/status/1856720727103148456

https://x.com/Q_YogaMacFlower/status/1856721733392150840

https://x.com/scottmacleod/status/1856721945049419827

https://x.com/WUaSPress/status/1856724072341618859





Retweeting -

New release of GWAS summary statistics for 2,502 clinical endpoints from
@FinnGen_FI
🇫🇮🧬

👉N>500,000 individuals, ∼10% of Finland's population
👉Together with UKBB, FinnGen offers the best resource for PheWAS out there

📊Instructions to access the data: https://finngen.fi/en/access_results


https://x.com/MariosGeorgakis/status/1855229212258443456




AND -

Asked #GeminiAIOnGenetics about 

Genetics of Protuberances - M Nov 11, 2024

'How do genetics or genomics create Gene protuberances such as fins or Mammoth tusks or Mammoth trunk or bird beaks?' 

"The development of protuberances like fins, tusks, trunks, and beaks is a complex process involving the interplay of genetics and environmental factors. Here's a breakdown of the genetic mechanisms:

Genetic Basis
 * Genes Encode Proteins: Genes are segments of DNA that provide instructions for building proteins. These proteins, in turn, perform various functions within the organism, including structural development.
 * Regulatory Genes: Some genes, known as regulatory genes, control the activity of other genes. They determine when, where, and to what extent certain genes are expressed.
 * Morphogenesis: The process of shaping an organism's form is called morphogenesis. It involves a complex interplay between genes and their products, including proteins and signaling molecules. These molecules guide cell growth, differentiation, and migration, leading to the formation of specific structures like fins, tusks, trunks, and beaks.

Evolutionary Changes
 * Mutations: Mutations, changes in the DNA sequence, can introduce new variations in genes. Some mutations may affect the structure or function of proteins involved in development, leading to changes in the shape or size of structures.
 * Natural Selection: Over generations, natural selection favors individuals with traits that enhance their survival and reproduction. If a mutation leads to a protuberance that provides an advantage, such as increased food gathering ability or protection from predators, individuals with that trait are more likely to survive and pass on their genes to the next generation.
 * Genetic Drift: Random changes in gene frequencies within a population, known as genetic drift, can also contribute to the evolution of protuberances. This is particularly important in small populations, where chance events can have a significant impact on the genetic makeup of the population.

Specific Examples
 * Fins: Genes control the development of fin buds, which then grow and differentiate into various fin structures. Mutations in these genes can lead to changes in fin shape, size, and number.
 * Mammoth Tusks: Genes regulate the growth and development of tusks, which are modified incisors. Mutations in these genes can result in variations in tusk size, shape, and curvature.
 * Mammoth Trunk: The development of the mammoth trunk is a complex process involving multiple genes. Mutations in these genes can affect the length, flexibility, and muscle development of the trunk.
 * Bird Beaks: Genes control the growth and shape of the beak, including the size, shape, and curvature of the bill. Mutations in these genes can lead to variations in beak morphology, which can be adaptive for different feeding strategies.

Genomics and Epigenetics
 * Genomics: The study of entire genomes provides insights into the genetic basis of complex traits like protuberances. By comparing the genomes of different species, researchers can identify genes involved in the development of specific structures.
 * Epigenetics: Epigenetic modifications, such as DNA methylation and histone acetylation, can influence gene expression without altering the underlying DNA sequence. These modifications can play a role in the development of protuberances by affecting the activity of genes involved in morphogenesis. 

In conclusion, the development of protuberances is a complex process involving the interaction of genes, environmental factors, and evolutionary forces. By studying the genetic and genomic basis of these structures, we can gain a better understanding of the mechanisms that shape the diversity of life on Earth.








2 d

from 
TWAS studies too  too 

Marios Georgakis
@MariosGeorgakis
Nov 17
scPrediXcan offers a TWAS (transcriptome-wide association study) framework at a single-cell level❗️


https://x.com/MariosGeorgakis/status/1858151606065246316

Abstract
Transcriptome-wide association studies (TWAS) help identify disease causing genes, but
often fail to pinpoint disease mechanisms at the cellular level because of the limited sample
sizes and sparsity of cell-type–specific expression data. Here we propose scPrediXcan which
integrates state-of-the-art deep learning approaches that predict epigenetic features from DNA
sequences with the canonical TWAS framework. Our prediction approach,





2 e

A transcriptome is the complete set of RNA transcripts, or gene readouts, in a cell or tissue at a specific time or condition. It includes messenger RNA (mRNA), ribosomal RNA, transfer RNA, micro-RNA, and other noncoding RNAs. 
The transcriptome is different from the genome, which is relatively stable, because the transcriptome can change depending on environmental conditions and an organism's stage of development. The study of the transcriptome is called transcriptomics, which reveals which genes are being actively expressed in a cell at any given time. 
Transcriptomics has many applications, including:
  • Antibiotic discovery
    Transcriptomics can help elucidate molecular mechanisms involved in antibiotic resistance. 
  • Pigment synthesis
    Transcriptome analysis can help explain how microalgae synthesize pigments. 
  • Brain development
    Transcriptomics can help explain how changes in gene expression drive brain development and how environmental factors can influence those changes



2 f 

Twitter - #AgingReversalMachine w - How to view Google Street View in a smart meeting room - as potentially  #AgingReversalMachine


For a #PHYSICALDIGITAL #RealsiticVirtualEarthForAgingReversal build out from


For a #PHYSICALDIGITAL #RealsiticVirtualEarthForAgingReversal build out from
"#eRapid: #MultiplexedElectrochemicalSensors for Fast, Accurate, Portable Diagnostics: A fouling-resistant...
https://wyss.harvard.edu/technology/erapid-multiplexed-electrochemical-sensors-for-fast-accurate-portable-diagnostics/ WITH SENSOR Digitized FIRST in #GSV in https://youtu.be/q9FBhEAXRY4 ~

GSV room pic 



Sensor pic 







* * 





Monday, March 25, 2024
Dionysia bryoides: Recording of M 3/25/24 open @WorldUnivAndSch @WUaSPress #WUaSNewsQA #ToolifyAIWUaS #MITOCW #AgingReversalMachine 


*

#AgingReversalMachine w
"eRapid: Multiplexed Electroch Sensors" binds w molecular event  https://wyss.harvard.edu/technology/erapid-multiplexed-electrochemical-sensors-for-fast-accurate-portable-diagnostics/ w "How to view Street View in a smart meeting room" w TIME SLIDER 
https://youtu.be/q9FBhEAXRY4 w #AvatarAgentElectronicHealthRecords 



Expanded - 

#AgingReversalMachine build out from
"eRapid: Multiplexed Electrochemical Sensors for Fast, Accurate, Portable Diagnostics" 'binds w molecular event' https://wyss.harvard.edu/technology/erapid-multiplexed-electrochemical-sensors-for-fast-accurate-portable-diagnostics/ with "How to view Street View in a smart meeting room" with TIME SLIDER 
https://youtu.be/q9FBhEAXRY4 with #AvatarAgentElectronicHealthRecords 
with @geochurch AND Adding Genes back into people (via vaccines initially https://m.youtube.com/watch?v=bnCEIPQFNnk?



*

#AgingReversalMachine #AgingReversalGenetics in #RealisticVirtualEarthForAgingReversal 

"How to view Google Street View in a smart meeting room" (Igloo Vision)
 - as potential #AgingReversalMachine ?

#AvatarAgentElectronicHealthRecords 


*
How to plan for #AgingReversalMachine #AgingReversalGenetics in #SpeciesBrains in #RealisticVirtualEarthForBrains: Transcriptomic reprogramming for neuronal age reversal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066999/ w wiki #CitizensScience #FlywireConnectome @AmyNeurons @AMPlesa @EBoyden3 @GeoChurch?

https://twitter.com/WorldUnivAndSch/status/1771214580519248376




Retweeting -

I never get tired of looking at neurons. Here are some posters I made from @quorumetrix's cool @FlyWireNews renders. Explore the connectome: codex.flywire.ai



AND 

"How to view Google Street View in a smart meeting room"
 - as potential #AgingReversalMachine ?

WOW: "How to view #GStreetView.." https://youtu.be/q9FBhEAXRY4 as pot. #AgingReversalMachine & #WUaSMultimediaRoom in Hospitals & for #WUaSSpaceTravel w #GSV in ceiling, hiking #PacificCrestTrail, #IndiaOnBicycle, but where #GPegman & #TimeSlider as #AvatarAgentElectronicHealthRecord?

https://twitter.com/WorldUnivAndSch/status/1769357648980308421

https://twitter.com/scottmacleod/status/1769357814831448321






AND 

WOW: "How to view #GStreetView in a smart meeting room" https://youtu.be/q9FBhEAXRY4 as pot. #AgingReversalMachine & #WUaSMultimediaRoom in Hospitals in 200 countries too & for #WUaSSpaceTravel with #StreetView in ceiling, hiking #PacificCrestTrail again, Exploring India on bicycle from home, but where are #GPegman as our #AvatarAgentElectronicHealthRecord #DigitalTwin & for #TeleroboticSurgery & #TimeSlider?



AND 

"How to view Google Street View in a smart meeting room" (Igloo Vision)

Great - "How to view #GStreetView in a smart meeting room" https://youtu.be/q9FBhEAXRY4 How to #TimeSlide back >#WoolyMammoth s' epoch as species & have a Mammoth walk thru middle of room, then Zoom into #GCellView #GMoleculeView to view #MammothGenes w living elephant & w #VisionPro?

https://twitter.com/WorldUnivAndSch/status/1769003792802975894

https://twitter.com/scottmacleod/status/1769003878438076660





How to view Google Street View in a smart meeting room (Igloo vision)

https://youtu.be/q9FBhEAXRY4




AND

Great - "How to view Google Street View in a smart meeting room" https://youtu.be/q9FBhEAXRY4 How to #TimeSlide back to #WoolyMammoth s' epoch as species & have a Mammoth walk into middle of room, then Zoom in to #GCellView #GMoleculeView to view #MammothGenes & with a living elephant in the physical room too, & even with  #AppleVisionPro #DigitalMask?






Agenda item 3





languages at WUaS, Scottish Gaelic, Scots language, English ... AND soccer even for learning machine learning re the soccer. match HIGHLIGHTS' video  - 





Agenda item 4

WUaS symphony orchestra online from home for WUaS students to play with great conductors and brilliant and fun music ... re the Science Fiction of StarWars too - 


Brilliant & Fun! & for #WUaSstudents to #PlayWithFromHome!
John Williams & #BostonSymphonyOrchestra - Imperial March (From Star Wars: The Empire Strikes Back) #DeutscheGrammophone 

















--


Society, Information Technology, and the Global University (2025, forthcoming) 

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- PO Box 442, Canyon, CA 94516 
- 5816 Callowhill St., Pittsburgh, PA 15206

1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 
 World University and School - http://worlduniversityandschool.org  

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research -  scottmacleod.com 






























https://en.wikipedia.org/wiki/Honey_locust

https://commons.wikimedia.org/wiki/Gleditsia_triacanthos

https://commons.wikimedia.org/wiki/Category:Gleditsia_triacanthos


...



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