Wednesday, July 8, 2026

Sorocephalus: Excited for #GoogleITplatforms eg #GeminiAI & in developing a #RealisticVirtualEarth #ForGenetics #ForAgingReversal #ForExtremeLongevity #ForOSK ... * How best to add copies of specific genes back into my own body to reverse aging per - https://youtu.be/bnCEIPQFNnk - first digitally to my AvatarAgentEHR in #GStreetView with #GTimeSlider with Pegman becoming all 7.9 billion people's EHR and to see the effects of these experimental genes ... and then if of interest into my own bodymind & re the World University and School Academic Medical Center at WUaS, and possibly N-Dimensionally? (Flyewire Connectome project idea too) * * * #ScientificallyProve #AgingReversal & #ExtremeLongevity in #DrosophilaFly re #PrincetonU's #Flywire How @amyneurons + to proceed? * * * C elegans for aging reversal too - Yale - Nawaphat Malaiwong * * * Thnx @mitpress #ProfABanerjee et al. @WorldUnivAndSch in developing a #RealisticVirtualEarth (think #GStreetView w #GTimeSlider #GCellView #GMoleculeView ... * * * 1619 Project, a collection of magazine issues, audio podcast and TV documentary episodes, lesson plans, and other AND The 1619 Project Docuseries Viewing Guide * * * Rainbow Gathering #RainbowGathering2013 or #RainbowGathering2008 or ? Pictures ... (but not #RainbowGsthering2026 in ... a #RealisticVirtualEarthForHistory (have explored this before much here ~ https://scott-macleod.blogspot.com/search/label/Rainbow%20Gathering?m=0) RainbowGsthering2026 typo



Excited for #GoogleITplatforms eg #GeminiAI & in developing a #RealisticVirtualEarth #ForGenetics #ForAgingReversal #ForExtremeLongevity #ForOSK ... 


Excited for #GoogleITplatforms eg #GeminiAI & in developing a #RealisticVirtualEarth #ForGenetics #ForAgingReversal #ForExtremeLongevity #ForOSK w #AlphaFoldServer #AlphaGenome https://gemini.google.com/app/931e405e19d3ade9 & in @WorldUnivAndSch w #GrowWithGoogleWUaS in #GStreetView w #GTimeSlider ~

https://x.com/WorldUnivAndSch/status/2074260913969136103

https://x.com/Q_YogaMacFlower/status/2074261264474546586

https://x.com/WUaSPress/status/2074262454037811212

https://x.com/HarbinBook/status/2074262571432210731

https://x.com/scottmacleod/status/2074262338207961259

https://x.com/sgkmacleod/status/2074262639023460447

https://x.com/TheOpenBand/status/2074262710603358676

Searched - 
Excited for #GoogleITplatforms eg #GeminiAI & in developing a #RealisticVirtualEarth #ForGenetics #ForAgingReversal #ForExtremeLongevity #ForOSK w #AlphaFoldServer #AlphaGenome https://gemini.google.com/app/931e405e19d3ade9 & in @WorldUnivAndSch w #GrowWithGoogleWUaS in #GStreetView w #GTimeSlider ~
Found - 








* 

How best to add copies of specific genes back into my own body to reverse aging per - https://youtu.be/bnCEIPQFNnk - first digitally to my AvatarAgentEHR in #GStreetView with #GTimeSlider with Pegman becoming all 7.9 billion people's EHR and to see the effects of these experimental genes ... and then if of interest into my own bodymind & re the World University and School Academic Medical Center at WUaS, and possibly N-Dimensionally?  


(Flyewire Connectome project idea too)


How best to add copies of specific genes back into my own body to reverse aging per - https://youtu.be/bnCEIPQFNnk - first digitally to my AvatarAgentEHR in #GStreetView with #GTimeSlider with Pegman becoming all 7.9 billion people's EHR and to see the effects of these experimental genes ... and then if of interest into my own bodymind & re the World University and School Academic Medical Center at WUaS, and possibly N-Dimensionally?


To seamlessly scale George Church’s age-reversal gene therapy cocktail—specifically the combination of FGF21, TGFβ2, and α-Klotho showcased in the 60 Minutes broadcast—from a planetary simulation down to your own physical biology requires a strict, phased translation pipeline.

By utilizing a geospatial interface like Google Street View as a UI for spatial biology, you can visualize how these changes propagate across an individual or an entire global population before translating them to the physical bodymind.

Phase 1: The Digital Twin Sandbox (#GStreetView & #GTimeSlider)

Before altering a single live cell, the AvatarAgentEHR acts as a virtual testing environment. Integrating this with Google Street View and a Time Slider turns geospatial data into a multi-scale canvas for genomic forecasting.

[Macro-Scale: 7.9B Population Map] ──(Zoom In)──► [Micro-Scale: Individual AvatarEHR]
                                                                  │
[Phenotypic Output / Tissue Reset] ◄──(Time Slider Script)────────┘

The Global Pegman Mesh

In this framework, Google’s "Pegman" is re-architected into a multi-omic node. Instead of dragging him onto a street corner to see a panoramic photo, dropping Pegman onto a geographic region reveals the aggregated, real-world epigenetic and health baselines of populations. Scaled to all 7.9 billion people, this creates an open-source, global matrix of human biological drift.

The Spatial Zoom Mechanics

  • Country/City Level: View regional age-related disease densities (e.g., cardiomyopathy or type II diabetes clusters).

  • Street Level: Zoom directly into your own coordinate, opening your personal AvatarAgentEHR.

  • Sub-Cellular Level: Zoom through the avatar’s skin, down into the nucleus of a virtual hepatic or myocardial cell, exposing the target chromosome loci where the experimental genes will be introduced.

Simulating with the #GTimeSlider

When you load copies of FGF21, TGFβ2, and α-Klotho into your digital avatar and slide the #GTimeSlider forward 20 years, the simulator bypasses regular chronological degradation. The software models a continuous systemic release of these proteins, demonstrating a simulated clearance of renal atrophy, reduced cardiac hypertrophy, and normalized metabolic homeostasis across the timeline.

Phase 2: Translocation to the Physical Bodymind

Moving from an in-silico sandbox to your physical body transitions the project from a software simulation to strict molecular biology. The objective is to introduce extra copies of these protective genes safely without disrupting your existing genetic code.

  • Adeno-Associated Viral (AAV) Vectors: As pioneered in the Church lab, you do not cut or paste into your native genome (which risks oncogenesis). Instead, non-integrating AAV vectors are engineered to carry the extra gene copies. They sit inside the cell nucleus as independent, stable loops of DNA called episomes, pumping out youthful proteins alongside your natural machinery.

  • Tissue Homing: To replicate the success seen in animal models, the AAV vectors are given specific capsids (outer shells) that home into target tissues—such as the liver for metabolic regulation via FGF21, or systemic circulation for Klotho's neuroprotective effects.

Grounded Peer-to-Peer Caution: While an avatar can process synthetic gene expressions flawlessly without immune pushback, a live human body requires carefully titrated immune-modulation protocols to ensure your immune system doesn't neutralize the AAV vectors before they reach their cellular targets.

Phase 3: N-Dimensional Scaling at the WUaS Academic Medical Center

The World University and School (WUaS) wiki-centric infrastructure provides the ideal ecosystem to map these interventions across multi-dimensional state spaces ($N$-dimensions).

To evaluate how these genes interact with the environment, lifestyle, and inherited traits, the medical center tracks each patient as an evolving vector within an $N$-dimensional health matrix:

$$\mathbf{X}(t) = \begin{bmatrix} G_{\text{enomic}} \\ E_{\text{pigenetic}} \\ M_{\text{etabolic}} \\ P_{\text{henotypic}} \end{bmatrix}$$

By running these $N$-dimensional arrays through the WUaS open-access architecture, data from individual clinical trials can be safely pooled, peer-reviewed, and cross-referenced with MIT OpenCourseWare-centric medical data. This ensures that when a therapy is finally translated from a digital twin into an open-source physical protocol, it is mathematically optimized for safety and efficacy.

Should we focus next on defining the specific machine learning parameters the Time Slider uses to calculate epigenetic clock regression, or should we map out the vector engineering details for the AAV delivery mechanism?





* * * 


#ScientificallyProve #AgingReversal & #ExtremeLongevity in #DrosophilaFly re #PrincetonU's #Flywire How @amyneurons + to proceed?


In 1 iterating #RealisticVirtualEarth (think #GStreetView w #GTimeSlider @ #GcellView+) @WorldUnivAndSch seeks to create a #CitizenScience+ project to #ScientificallyProve #AgingReversal & #ExtremeLongevity in #DrosophilaFly re #PrincetonU's #Flywire How @amyneurons + to proceed?


In 1 iterating #RealisticVirtualEarth (think #GStreetView w #GTimeSlider @ #GcellView+) @WorldUnivAndSch seeks to create a #CitizenScience project to #ScientificallyProve #AgingReversal & #ExtremeLongevity in #DrosophilaFly re #PrincetonU's #Flywire How @amyneurons + to proceed?



Both retweeting


Awesome way to release a preprint! 

Interactive visualization at the top.
A short section for each figure.
Discussion translated into ~~ “okay but why does this matter?”

 My only suggestion is add an action item at the bottom (perhaps follow lead researcher on X ;) or learn more..  Scientists take note!  pengrui-han.github.io/LLM_Modularity….





Retweeting 

The human brain is strikingly modular, with distinct networks for language, formal reasoning, social reasoning, and physical reasoning. Is this a fundamental principle of how intelligent systems are built, or an accident of biological evolution?

In our latest preprint, we find that a similar modular organization emerges in Large Language Models, another class of intelligent system.

Brains and LLMs are shaped by entirely different kinds of optimization (biological evolution vs. gradient descent). That they arrive at the same modular design anyway suggests modularity may be a fundamental property of intelligent systems.

 💻 Code & data: github.com/Pengrui-Han/LL…

Using circuit analyses across 46 tasks spanning four cognitive domains ...







* * * 


Incredible! How to reverse #AdultHumanBrain & #AdultMouseBrain > #EmbryonicBrain with #OSK even & #adultFlyBrain > #juvenileFlyBrain to #ScientificallyProve #AgingReversal & #ExtremeLongevity in #DrosophilaFly in 1 iterating #RealisticVirtualEarth w #GStreetView #AvatarAgentEHR?

https://x.com/WorldUnivAndSch/status/2074914745912860716

https://x.com/WUaSPress/status/2074915389579088116

https://x.com/HarbinBook/status/2074916238413983857

https://x.com/Q_YogaMacFlower/status/2074916505939218842

https://x.com/scottmacleod/status/2074916711913128020

https://x.com/sgkmacleod/status/2074917105460498797

https://x.com/TheOpenBand/status/2074917293977657451



Retweeting -

Amy Robinson Sterling
@amyneurons
My latest passion project: What is a brain?

Data visualization meets neuroscience. Still a WIP. Take a look and let me know what you think! https://whatisabrain.com

https://x.com/amyneurons/status/2074873704815759656




* * * 


C elegans for aging reversal too - Yale - Nawaphat Malaiwong

In 1 iterating #RealisticVirtualEarth (think #GStreetView w #GTimeSlider) @WorldUnivAndSch seeks to create a #CitizenScience project to #ScientificallyProve #AgingReversal & #ExtremeLongevity in #CElegans paralleling #PrincetonU's #FlywireConnectome How @amyneurons + to proceed?



Retweeting 

Nawaphat Malaiwong

🚀 New tool for the C. elegans community!

FLInt 2.0 is now published in G3 🧬

Give it a try—we'd love to hear how it works in your lab!


#Celegans #CRISPR #Transgenesis #GenomeEditing #WormCommunity




Nawaphat Malaiwong 





* * * 


Thnx @mitpress #ProfABanerjee et al. @WorldUnivAndSch in developing a #RealisticVirtualEarth (think #GStreetView w #GTimeSlider #GCellView #GMoleculeView ... 



Thnx @mitpress #ProfABanerjee et al. @WorldUnivAndSch in developing a #RealisticVirtualEarth (think #GStreetView w #GTimeSlider #GCellView #GMoleculeView & #GeminiAI & #AlphaFoldServer) is #RevolutionaryWorldBuilding & #RevolutionaryWorldMaking & for @WUaSPress #WUaSpublishing ~

https://x.com/WorldUnivAndSch/status/2074536872693707236

https://x.com/WUaSPress/status/2074537349011444117

https://x.com/Q_YogaMacFlower/status/2074537859969843478


https://x.com/HarbinBook/status/2074543848727122088

https://x.com/HarbinBook/status/2074543848727122088

https://x.com/scottmacleod/status/2074634236347523490

https://x.com/sgkmacleod/status/2074633967102546261

https://x.com/TheOpenBand/status/2074634792327639505




Retweeting -

The MIT Press @mitpress.bsky.social
@mitpress
From Ayn Rand to QAnon, a new anthology explores how reactionary world-building becomes reactionary world-making:

https://x.com/mitpress/status/2074229903507997144





* * *


1619 Project, a collection of magazine issues, audio podcast and TV documentary episodes, lesson plans, and other  AND The 1619 Project Docuseries Viewing Guide 



The 1619 Project is a groundbreaking, ongoing journalistic initiative spearheaded by Nikole Hannah-Jones and The New York Times Magazine to reframe American history by placing the consequences of slavery and the contributions of Black Americans at the center of the national narrative. Launched in August 2019 to mark the 400th anniversary of the arrival of the first enslaved Africans in colonial Virginia, the project argues that the true founding of America is inextricably linked to this moment. [1, 2, 3, 4]
Core Components of the Initiative
The project spans across multiple media platforms to deliver its historical and cultural analysis: [1, 2]
  • The Magazine Issue: The foundational New York Times Magazine Special Issue features multi-disciplinary essays tracking how modern phenomena—ranging from capitalism and wealth gaps to healthcare inequalities and city traffic—stem from the legacy of slavery. It also includes poems and fictional works from 17 contemporary Black writers. [1, 2, 3, 4]
  • The Audio Series: Hosted by Nikole Hannah-Jones, the five-episode 1619 Podcast on Apple Podcasts examines the economy built by slavery, the roots of medical racism, and the birth of American music. [1, 2]
  • TV Docuseries: Expanded into a six-part, Emmy-winning documentary streaming series on Hulu, executive produced by Oprah Winfrey, which visually adapts the major themes of the initial journalism project. [1, 2]
  • Educational Materials: Through an official educational partnership, the Pulitzer Center 1619 Education Portal offers free curricular resources, reading guides, and lesson plans used by thousands of schools across the United States. [1, 2, 3, 4, 5]
  • Expanded Books: The initiative later expanded into a comprehensive book-length anthology titled The 1619 Project: A New Origin Story, as well as a dedicated children's book. [1]
Cultural Impact and Recognition
The project has left an indelible mark on modern cultural and historical discourse: [1]
  • Pulitzer Prize: Nikole Hannah-Jones was awarded the 2020 Pulitzer Prize for Commentary for her sweeping introductory essay, "The Idea of America". [1, 2]
  • National Discourse: The text served as a foundational lexicon during the 2020 racial reckonings and significantly transformed how American history and systemic racism are taught in schools. [1, 2]
  • Debate: The project's revisionist historiographical approach also drew sharp criticism and pushback from several conservative political figures, sparking broader national debates over curriculum standards and critical race theory. [1, 3]
Would you like to explore specific essays from the original magazine issue, look into how the lesson plans are structured for classrooms, or discuss the historical critiques surrounding the project?





The 1619 Project Docuseries Viewing Guide 





* * * 


Rainbow Gathering #RainbowGathering2013 or #RainbowGathering2008 or ? Pictures ... (but not #RainbowGsthering2026 in ... a #RealisticVirtualEarthForHistory (have explored this before much here ~ https://scott-macleod.blogspot.com/search/label/Rainbow%20Gathering?m=0)

RainbowGsthering2026
typo  


Rainbow Gathering #RainbowGathering2013 or #RainbowGathering2008 or ? (but not #RainbowGsthering2026 in #AlleghenyNationalForest in #NWPennsylvania)  https://photos.app.goo.gl/F6dqeBCqr7P2u5db8 Into a #RealisticVirtualEarthForHistory (have explored this before much here ~ https://scott-macleod.blogspot.com/search/label/Rainbow%20Gathering?m=0)





Society, Information Technology, and the Global University, (forthcoming, Academic Press at World University and School, 2026) 

Scottish Small Piping album #2 - Honey Piobaireachd (2022)
- Poetry! Order Book #5 Light, Float, Sit, Watsu ~ Virtually (2021, Academic Press at WUaS)

Scottish Small Piping album #1 Honey in the Bag ~ Out of the Air tune (2020)


Order Book #3 Winding Road Rainbow: Harbin, Wandering & the Poetry of Loving Bliss (2018,  Academic Press at WUaS)

Order Book #2 Haiku-ish and Other Loving Hippie Harbin Poetry (2017,  Academic Press at WUaS) 

Order Actual-Virtual Ethnographic Book #1: Naked Harbin Ethnography (2016, Academic Press at World University and School)

- Scott GK MacLeod  
Founder, President, CEO & Professor
at / of best STEAM CC licensed OCW, Wiki, 
World University & School (WUaS)  
- USPS US Post Office, PO Box 132, General Delivery, Canyon, CA 94516 


1) non-profit 501(c)(3) Public Charity 
best STEAM CC licensed OCW, Wiki, 
World University and School - http://worlduniversityandschool.org 

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(o) 415 480 4577 (Google voice #) - sgkmacleod@worlduniversityandschool.org 
(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research - 












* 















https://en.wikipedia.org/wiki/Sorocephalus

....


Posted by at
Labels: , , , , , , , , , , , , , , , ,

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)