Dear George (Church), Yogi Jarvis Chen (in the Harvard TH Chan school of Public Health), Alex (Plesa, Wyss Institute at Harvard), Peter (Norvig, Google AI), Sundar (Pichai), Yoga friends & family in their 80s and 90s ~ Ma/Janie, and Alden (Briscoe - who went to Quaker George School in Philadelphia before Harvard college), & QuakerunitarianYogini & veterinarian & cousin Annie (Brown in NE Oregon) in her 60s, Dick (Robb MD, possibly posthumously, also an ophthalmology professor in Harvard Medical School), and Maitreyi (Mazumdar MD - a professor in Harvard Medical School too), Vivek (Buch MD, professor of surgery in the Stanford Medical School), MacLeod kin or family, Doortje (Van Kooten, and Angela, and your father Victor, and please forward), Valerie & Ed Smyth MDs, & Marlynn Wei MD JD (co-author of "The Harvard Medical School Guide to Yoga: 8 Weeks to Strength, Awareness, and Flexibility," 2017, Harvard Press), Pin/Sid Mazumdar, HHS, all,
Yoga greetings (as in 8 limbs of Yoga) from Orinda in the SF East Bay, for these email restorative Yoga explorations' on Saturday October 17, 2026 (and as we may live to 150 and well beyond:) ... around 8 am Your Time ...
1
How to explore with a #YogaGeneticsApp even Yoga-promising #RejuvenatingGenes such as SRSF1 and with YOGA asana INVERSIONS, in ways we can experiment with doing Yoga, and in our avatar agent electronic health records emerging from little G Pegman in a FORKED Google.Street View with time slider on the digital side ... and with a digital-physical #RealisticVirtualEarthForYoga?
1 a
How best to dev a #RealisticVirtualEarth a #RVEforYogaAsana #RVEforGeneExpression #RVEforSRSF1 in a #YogaGeneticsApp with modeling https://x.com/
& other #RejuvenatingGenes ?
1 b
Peter (Norvig), Bruce Brad MacLeod (CS emeritus professor at the Univ of Maine, and 1st cousin), Sundar (Pichai), others, how best to begin to create an iterating #YogaGeneticsApp potentially on our smartphones at World Univ & Sch in a #GrowWithGoogle program, and so that we doers of Yoga asana could be begin to experiment with Yoga asana expression of rejuvenating genes, such as #SRSF1gene ... and as scientists continue to develop AAV Adeno-associated virus (AAV) gene vaccines to deliver genes like #SRSF1 and possibly thousands of others - and for aging reversal? How for Yoga practitioners and explorers to begin to generate data (in our AvatarAgentEHR) even while doing Yoga inverted poses and their effects on #SRSF1 rejuvenating gene expression ? Potentially a WUaS generative AI Yoga research tool for people doing Yoga movements ...
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Let's explore inversions restoratively Yoga-wise, and re 'de-hunching over' my mother too re her asking about this ... with Yoga asana tomorrow around 8 am, your time ...
Beginning around 1:08:00 minute marker -
A
1:08
opening the chest area - per Yogini Angela (Farmer here in Greece)...
'almost like I have wings'
B
1:09:15
Viparti Karani explorations
Legs up wall, sacrum on brick ... and interweave one's fingers behind the block - with block on lowest or middle height ?? - and to explore opening your chest further eg at 1:11...
C
1:15
Then still with your pelvis on the block, draw your knees up over your body ..
D
1:17
Then come onto the floor off the block, and draw your neck long with your fingers behind your head in both directions
D a
release your arms onto the ground
E
1:18
Adho Mukha Svanasana (dog pose) explorations
F
1:19
And then some twists on your shins, or on a chair
until about 1;22
G
And then on your own,
explore doing Savasana ...
Of course you can explore Angela teaching further in this video ... and re your riffing with her Yoga words & in your further Yoga explorations.
In developing this potential
Yoga Genetics' App
possibly viewed in the back of digital glasses or VR Goggles, how might we begin to learn and experiment with even the gene expression of SRSF1 in Viparita Karani (and thousands of other potential rejuvenating gene expressions ... and as we could see them becoming expressed even? How would the possible digital glasses or head band we were wearing via contact with skin, or with / as brainwave headsets, stream SRSF1 gene expression and similar data via the web into our avatar agent EHR (emerging from Google Pegman) such that we could see differences in rejuvenating gene expressions as we changed Yoga poses ?) ... All brainstorming, since I don't know how Harvard's Alex Plesa with possibly George Church created this modeling - https://x.com/amplesa/
Yogically (as in 8 limbs of Yoga) as we may live to 150 and well beyond:) and in exploring this Yoga-wise , Desiderata prose poem greetings (https://www.desiderata.com/
Scott
AND
Saturday, October 10, 2026
Indian sandalwood flowers: Sat 10/10/26 - Restorative Yoga class on Saturdays (and as we may live to 150 and well beyond:)? * Yoga greetings (as in 8 limbs of Yoga) from Marin, north of SF in California, for these email restorative Yoga explorations' on Saturday October 10, 2026 (and as we may live to 150 and well beyond:) ... possibly even infinitely per George Church at the Harvard Aging Reversal and Drug Development conference to me in Cambridge, MA, by implication, on 10/2/26 ... around 8 am Your Time ... How to Yoga or join or merge extending in both directions at the same time, and re even reversing the arrow of time, and extending it infinitely (and in our avatar agent electronic health records from G.Street View with time slider from little G Pegman on the digital side ... and for digital-physical corresponding in a #RealisticVirtualEarthForYoga)
AND
am adding all of these restorative Yoga explorations here in an ongoing way -
Thursday, August 13, 2026
Lotus maculatus: Restorative Yoga explorations' classes' Blog posts since December 2025 with 'Yoga' blog label too here - https://scott-macleod.
AAAAAPS
some inquiries with Gemini AI about -
yoga asana and gene expression & SRSF1 gene studies
How best to dev a #RealisticVirtualEarth a #RVEforYogaAsana #RVEforGeneExpression #RVEforSRSF1 in a #YogaGeneticsApp with modeling https://x.com/amplesa/status/
& other #RejuvenatingGenes ?
https://x.com/Q_YogaMacFlower/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/sgkmacleod/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/sgkmacleod/
*
#SRSF1gene & other #RejuvenatingGenes
#SRSF1gene & other #RejuvenatingGenes list of all possible emerging targets even?
*
How best to develop a #RealisticVirtualEarth a #RVEforYogaAsana a #RVEforGeneExpression a #RVEforSRSF1 in a #Yoga GeneticsApp with such modeling as https://x.com/amplesa/
& w host of related RejuvenatingGenes ?
yoga asana and gene expression
How could one begin to study yoga asana and gene expression with regard to a specific gene, SRSF1 gene, in terms of aging reversal even?
While yoga positively impacts general gene expression and reduces inflammation, there are currently no studies linking specific asanas directly to the SRSF1 gene. To study this, researchers would use transcriptomic profiling to track whether physical practices can modulate RNA splicing factors. Because SRSF1 is a recently discovered genetic target for cellular rejuvenation, connecting everyday lifestyle habits to its specific activation remains an uncharted scientific frontier.
Are there any studies whatsoever of yoga asanas impact on specific genes and gene expression?
Yes, scientific studies have shown that yoga and mind-body interventions alter the expression of specific genes. Research using genomic profiling demonstrates that regular practice downregulates pro-inflammatory genes, such as NF-kB and TNF, while upregulating longevity- and repair-related genes, including SIRT-1, KLOTHO, AMPK, and the DNA-repair gene OGG1.
How could I begin to develop even transcriptomic profiling on my apple macbook air laptop computer to track whether physical yoga asena practices can modulate RNA splicing factors for the SRS F1 gene and newly in a realistic virtual earth for gene expression, think a forked Google Street view with time slider at the molecular level & also
How best to add #SRSF1 gene to #RealisticVirtualEarth #RVEforGeneExpression in our #DigitalHealthTwins #AvatarAgentEHR in #ForkedGoogleStreetView as #RVEforAgingReversal?
Retweeting -
Alex Plesa
In search for new rejuvenation factors, we tested our top 90 genes by overexpressing them in human aged skin fibroblasts. Using the resulting gene expression profiles, we mapped out a landscape of fibroblast aging and rejuvenation, and identified SRSF1 as a promising target. 4/8
And which Yoga asanas might be especially good to study regarding SRSF1 gene expression & aging reversal re above?
AAAAAPPS
Also -
Searched 'george church age reversal #HarvardARDD2026 new' Found reference to #SRSF1gene -
Searched 'george church age reversal #HarvardARDD2026 new' Found reference to #SRSF1gene - https://share.google/aimode/
Retweeting -
Alex Plesa
In search for new rejuvenation factors, we tested our top 90 genes by overexpressing them in human aged skin fibroblasts. Using the resulting gene expression profiles, we mapped out a landscape of fibroblast aging and rejuvenation, and identified SRSF1 as a promising target. 4/8
AAAAAPPPS
Jarvis Chen Harvard Chan School & Yoga ...
Jarvis Chen appointed lecturer on social and behavioral sciences
AAAAAPPPPS
Alex Plesa
AAAAAPPPPPS
And how to interoperate all the above with a #realisticVirtualHarbinHotSp
I'd like to visit a #
https://x.com/HarbinBook/
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/WorldUnivAndSch/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
I'd like to visit a realistic virtual harbin hot springs in a forked google street view with time slider and or make this for STEM ethnographic research per the book "Naked Harbin Ethnography" @ WUaS Press at World Univ & Sch building on MIT OCW in 7 languages eg with ai studio & for VR Goggles too - how?
*
https://en.wikipedia.org/wiki/Bingdi_lotus
....
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