9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #ZoomForThePeople #AgenticAI #TwinningAI #AIworkplatform ~
9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #ZoomForThePeople #AgenticAI
https://youtu.be/-5qey7FSykE
https://
-https://scott-macleod.
-https://www.youtube.com/@
*
Recording of
9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA
https://youtu.be/-5qey7FSykE
-https://
-https://scott-macleod.
-https://www.youtube.com/@
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
Video pic
https://x.com/WUaSPress/
9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA
https://youtu.be/-5qey7FSykE
-https://
-https://scott-macleod.
-https://www.youtube.com/@
9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA
— WorldUnivandSch (@WorldUnivAndSch) September 22, 2025
-https://t.co/skZExmv4uw
-https://t.co/HGL1qW8bvN
-https://t.co/J1sWsKFaEB
-https://t.co/5MgfBslDlO #QuakerColleges #ZoomForThePeople #AgenticAI #TwinningAI #RealisticVirtualEarthForMethylation #WUaSgenes~
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
Video pic
9/22/25 #MITOCWcentric wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA
— WUaSPress (@WUaSPress) September 22, 2025
-https://t.co/MzqRoX5ID6
-https://t.co/FJLYgpP6r2
-https://t.co/NdSMWvzSt6
-https://t.co/ZdmUSqVYJb #QuakerColleges #ZoomForThePeople #AgenticAI #TwinningAI #RealisticVirtualEarthForMethylation #WUaSgenes ~
https://x.com/WUaSPress/
* *
Universitians, friends, Friends at Friends Association for Higher Education (Quaker-informed FAHE), All,
Greetings from free MIT OCW-centric - https://ocw.mit.edu/ - wiki #GrowWithGoogleWUaS World Univ & Sch WUaS.
The next MIT OCW-centric - https://ocw.mit.edu/ & regarding previous versions of OCW - https://opencw.aprende.org/
Topic: M 9/22/25 open MIT OCW-centric wiki World Univ & Sch WUaS News and Q&A, with Zoom URL
Time: Sep 22, 2025 10:00 AM Pacific Time (US and Canada)
Join Zoom Meeting
https://us04web.zoom.us/j/
Meeting ID: 779 9002 1131
Passcode: pmcD6t
All the best, abolition-ally (a #MITOCW-centric wiki @WorldUnivAndSch #WUaSabolition movement is growing...
https://scott-macleod.
Scott
Scott GK MacLeod
Recording will be posted here -
https://www.youtube.com/@
Scott GK MacLeod
Recording will be posted here -
https://www.youtube.com/@
TwitterX and LinkedIN -
Open M 9/22/25 #MITOCWcentric #GrowWithGoogleWUaS wiki @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA meets at 10a Pacific Time with #ZoomWUaSURL:
https://
-https://scott-macleod.
-https://www.youtube.com/@
#ZoomForThePeople #AgenticAI #TwinningAI #AIworkplatform ~
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/TheOpenBand/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://lnkd.in/p/guTZphUq
https://lnkd.in/p/gPiEuPyK
https://lnkd.in/p/gqA-7c6t
https://
-https://scott-macleod.
-https://www.youtube.com/@
#ZoomForThePeople #AgenticAI #TwinningAI #AIworkplatform ~
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/TheOpenBand/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://lnkd.in/p/guTZphUq
https://lnkd.in/p/gPiEuPyK
https://lnkd.in/p/gqA-7c6t
* * * *
World University and School / WUaS
1st of 2 WUaS wings -
501 c 3 / similar non-profit https://www.
CC-4 licensed OCW.MIT.EDU - centric wing ... wiki ...
Agenda item 0
Monday, September 15, 2025
Bald eagle: 9/15/25 Recording of #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #GeminiAIreAIandML * (was - M 9/15/25 open MIT OCW-centric wiki World Univ & Sch WUaS News and Q&A, with Zoom URL)
9/15/25 Recording of #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #GeminiAIreAIandML
https://youtu.be/HX07JHmZTlU
Recording of M 9/15/25 #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #WUaSWeeklyBusinessMeeting
-https://youtu.be/HX07JHmZTlU
-https://
-https://scott-macleod.
-https://www.youtube.com/@
#GeminiAIreLearningAiML #GeminiAIreLegoRoboticsScratch #WUaSunivs~
Stanford arches' pic
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
Video pic -
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
No video image -
https://www.linkedin.com/
Both with video images -
https://www.linkedin.com/
https://www.linkedin.com/
Bald eagle: 9/15/25 Recording of #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #GeminiAIreAIandML * (was - M 9/15/25 open MIT OCW-centric wiki World Univ & Sch WUaS News and Q&A, with Zoom URL)
9/15/25 Recording of #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #GeminiAIreAIandML
https://youtu.be/HX07JHmZTlU
Recording of M 9/15/25 #MITOCW-centric @WorldUnivAndSch @WUaSPress #WUaSNewsAndQA #WUaSWeeklyBusinessMeeting
-https://youtu.be/HX07JHmZTlU
-https://
-https://scott-macleod.
-https://www.youtube.com/@
#GeminiAIreLearningAiML #GeminiAIreLegoRoboticsScratch #WUaSunivs~
Stanford arches' pic
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
Video pic -
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
No video image -
https://www.linkedin.com/
Both with video images -
https://www.linkedin.com/
https://www.linkedin.com/
Agenda item 1
The #QuakerColleges in US for ex don't have #MedicalSchools or #LawSchools or offer PhDs - & haven't graduated any #ComputerSciencePhDs or #CSMastersDegrees that I know of; Free #MITOCW-centric @WorldUnivAndSch seeks to do this online in all 200 countries https://wiki.
The #QuakerColleges in US for ex don't have #MedicalSchools or #LawSchools or offer PhDs - & haven't graduated any #ComputerSciencePhDs or #CSMastersDegrees that I know of; Free #MITOCW-centric @WorldUnivAndSch seeks to do this online in all 200 countries https://wiki.
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
Languages - in all 200 countries -
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
1 A
The #QuakerColleges https://
#BrynMawrCollege
#EarlhamCollege
#FriendsUniversity
#HaverfordCollege
#SwarthmoreCollege
#WilliamPennUniversity #FreeWUaSdegrees fr #FriendlyInformed #MITOCW-centric @WorldUnivAndSch #MedicalSchoolsWUaS #LawSchoolsWUaS #PhDsWUaS ~
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
The #QuakerColleges in US for ex don't have #MedicalSchools or #LawSchools or offer PhDs - & haven't graduated any #ComputerSciencePhDs or #CSMastersDegrees that I know of; Free #MITOCW-centric @WorldUnivAndSch seeks to do this online in all 200 countries https://wiki.
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
Languages - in all 200 countries -
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
1 A
The #QuakerColleges https://
#BrynMawrCollege
#EarlhamCollege
#FriendsUniversity
#HaverfordCollege
#SwarthmoreCollege
#WilliamPennUniversity #FreeWUaSdegrees fr #FriendlyInformed #MITOCW-centric @WorldUnivAndSch #MedicalSchoolsWUaS #LawSchoolsWUaS #PhDsWUaS ~
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
Agenda item 2
Fantastic #EricYuanCEO #AparnaBawaCOO #SmitaHashimCPO : #Zoomtopia2025 #ZoomForThePeople W 9/17/25 & re #AgenticAI !
GREAT @ericsyuan @AparnaBawa @smitahashim #Zoomtopia2025 #ZoomForThePeople W 9/17/25 & #AgenticAI ! How might https://ocw.mit.edu/ -
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
2 A
Fantastic #EricYuanCEO #AparnaBawaCOO #SmitaHashimCPO : #Zoomtopia2025 #ZoomForThePeople W 9/17/25 #AIworkplatform & #TwinningAI Much relevance for #MITOCW-centric wiki @WorldUnivAndSch in ~200 countries & 7k langs & @WUaSPress / #WUaSEducationalServicesStores re #AiAndMLWUaS esp
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
Retweeting -
Zoom
@Zoom
And that’s a wrap on #Zoomtopia2025!
Here’s a quick recap:
Groundbreaking AI innovations
Insights from industry leaders like Sal Khan, Marc Andreessen, Hayden Brown and more
7 curated tracks packed with practical takeaways
Actionable tips to level up your workday
A big thank you to everyone who joined us!
Catch the full replay — link in comments!
https://x.com/Zoom/status/
2 B
agentic ai
Agentic AI refers to autonomous, goal-oriented systems that can independently perceive, reason, plan, and act to achieve complex, multi-step objectives with minimal human oversight. Unlike traditional AI, which is reactive and follows predefined rules, agentic AI proactively learns and adapts to dynamic environments
2 C
Lego Masters Will Arnett
GREAT @ericsyuan @AparnaBawa @smitahashim #Zoomtopia2025 #ZoomForThePeople W 9/17/25 & #AgenticAI ! How might https://ocw.mit.edu/ -
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/WUaSPress/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
2 A
Fantastic #EricYuanCEO #AparnaBawaCOO #SmitaHashimCPO : #Zoomtopia2025 #ZoomForThePeople W 9/17/25 #AIworkplatform & #TwinningAI Much relevance for #MITOCW-centric wiki @WorldUnivAndSch in ~200 countries & 7k langs & @WUaSPress / #WUaSEducationalServicesStores re #AiAndMLWUaS esp
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
Retweeting -
Zoom
@Zoom
And that’s a wrap on #Zoomtopia2025!
Here’s a quick recap:
Groundbreaking AI innovations Insights from industry leaders like Sal Khan, Marc Andreessen, Hayden Brown and more 7 curated tracks packed with practical takeaways Actionable tips to level up your workday A big thank you to everyone who joined us!
Catch the full replay — link in comments!
https://x.com/Zoom/status/
2 B
agentic ai
Agentic AI refers to autonomous, goal-oriented systems that can independently perceive, reason, plan, and act to achieve complex, multi-step objectives with minimal human oversight. Unlike traditional AI, which is reactive and follows predefined rules, agentic AI proactively learns and adapts to dynamic environments
2 C
Lego Masters Will Arnett
searched on
'will arnett lego masters mindstorms robotics'
and found nothing
Agentic AI of Will Arnett in Lego Master's TV show could be developed to reach out to kids regarding Lego Robotics and to play with Lego Spike Prime robotics' kits too ?
2 D
Questions -
To Zoom's presenter at Upwork Hayden Brown,
ARE THEY BUILDING with Lego Robotics’ Kits, like Lego Spike Prime Robotics? .. where MIT OCW-centric wiki World Univ & Sch seeks to make #WUaSHomeRobootics central to our online free WUaS degrees from home …. And WUaS is an authorized reseller of 3 Lego Robotics’ kits - http://
AND
2 E
'will arnett lego masters mindstorms robotics'
and found nothing
Agentic AI of Will Arnett in Lego Master's TV show could be developed to reach out to kids regarding Lego Robotics and to play with Lego Spike Prime robotics' kits too ?
2 D
Questions -
To Zoom's presenter at Upwork Hayden Brown,
ARE THEY BUILDING with Lego Robotics’ Kits, like Lego Spike Prime Robotics? .. where MIT OCW-centric wiki World Univ & Sch seeks to make #WUaSHomeRobootics central to our online free WUaS degrees from home …. And WUaS is an authorized reseller of 3 Lego Robotics’ kits - http://
AND
2 E
Great @EricYuan, Marc Andreessen - A #
https://scott-macleod.
Agenda item 3
What #AgingReversal #GeneticDrugTherapies are likely to work for #MuscleWastingReversal & #SpinalCompressionReversal & possibly per 1 variable - #heightWUaS? What #YogaGenetics with #YogaEthics for performance - #HigherFasterStronger & more supple bodies https://scott-macleod.
What #AgingReversal #GeneticDrugTherapies are likely to work for #MuscleWastingReversal & #SpinalCompressionReversal & possibly per 1 variable - #heightWUaS? What #YogaGenetics with #YogaEthics for performance - #HigherFasterStronger & more supple bodies https://scott-macleod.
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
3 B
Without a shot or a vaccine, how to feed #CElegans to extend life 100x, from 3 weeks to 300 weeks, re #ExtremeLongevityWUaS #AgingReversalWUaS & per @geochurch https://youtu.be/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
3 BA
Gemini -
What #Aging Reversal #Genetic Drug Therapies are likely to work for #Muscle Wasting Reversal & #Spinal Compression Reversal & possibly per 1 variable - #height? What #Yoga Genetics with #Yoga Ethics #Aging Reversal #Genetic Drug Therapies are open targets or good candidates for randomized clinical trials for #Higher Faster Stronger & more supple bodies' performance?
This is a very complex and multi-faceted question that touches on areas of cutting-edge research, speculative science, and philosophical concepts. I'll break down the response into the different components you've asked about, based on the most current information available from scientific and medical research.
1. Genetic Drug Therapies for Muscle Wasting Reversal
...
3 C
What are the specific genes for higher faster stronger (more supple too) athletics ... and with application to people who might live over 122 years of age?
Gemini AI
For higher, faster, and stronger athletic performance, the genes ACTN3 (also known as the "speed gene") and ACE are the most studied and well-documented, with ACTN3 influencing fast-twitch muscle fibers and ACE impacting endurance and cardiovascular efficiency.
Here's a more detailed explanation:
ACTN3 (alpha-actinin-3):
This gene codes for a protein found in fast-twitch muscle fibers, which are crucial for explosive movements and power.
A common polymorphism (R577X) in the ACTN3 gene has two main variants:
RR genotype: Individuals with this genotype tend to have more fast-twitch muscle fibers and are often associated with strength and power-based sports.
3 D
higher, faster, stronger, all re Olympics too & re more supple bodie, also re "Yoga genetics"
"A Billion Years of Evolution in a Single Afternoon — George Church"
https://youtu.be/olmHHxFQwxo
Height
12 minute marker
Multigenic trait
http://www.scottmacleod.com/
https://scott-macleod.
What #AgingReversal #GeneticDrugTherapies are likely to work for #MuscleWastingReversal & #SpinalCompressionReversal & possibly per 1 variable - #heightWUaS? What #YogaGenetics with #YogaEthics for performance - #HigherFasterStronger & more supple bodies https://scott-macleod.
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/scottmacleod/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
3 B
Without a shot or a vaccine, how to feed #CElegans to extend life 100x, from 3 weeks to 300 weeks, re #ExtremeLongevityWUaS #AgingReversalWUaS & per @geochurch https://youtu.be/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
3 BA
Gemini -
What #Aging Reversal #Genetic Drug Therapies are likely to work for #Muscle Wasting Reversal & #Spinal Compression Reversal & possibly per 1 variable - #height? What #Yoga Genetics with #Yoga Ethics #Aging Reversal #Genetic Drug Therapies are open targets or good candidates for randomized clinical trials for #Higher Faster Stronger & more supple bodies' performance?
This is a very complex and multi-faceted question that touches on areas of cutting-edge research, speculative science, and philosophical concepts. I'll break down the response into the different components you've asked about, based on the most current information available from scientific and medical research.
1. Genetic Drug Therapies for Muscle Wasting Reversal
...
3 C
What are the specific genes for higher faster stronger (more supple too) athletics ... and with application to people who might live over 122 years of age?
Gemini AI
For higher, faster, and stronger athletic performance, the genes ACTN3 (also known as the "speed gene") and ACE are the most studied and well-documented, with ACTN3 influencing fast-twitch muscle fibers and ACE impacting endurance and cardiovascular efficiency.
Here's a more detailed explanation:
ACTN3 (alpha-actinin-3):
This gene codes for a protein found in fast-twitch muscle fibers, which are crucial for explosive movements and power.
A common polymorphism (R577X) in the ACTN3 gene has two main variants:
RR genotype: Individuals with this genotype tend to have more fast-twitch muscle fibers and are often associated with strength and power-based sports.
3 D
higher, faster, stronger, all re Olympics too & re more supple bodie, also re "Yoga genetics"
"A Billion Years of Evolution in a Single Afternoon — George Church"
https://youtu.be/olmHHxFQwxo
Height
12 minute marker
Multigenic trait
http://www.scottmacleod.com/
https://scott-macleod.
Agenda item 4
Caenorhabditis elegans
100x lifespan by adding copies of genes back into this organism per George Church's
How soon could humans reverse the aging process with genetic engineering?
https://youtu.be/bnCEIPQFNnk ?
How ?
4 A
100x lifespan by adding copies of genes back into this organism per George Church's
How soon could humans reverse the aging process with genetic engineering?
https://youtu.be/bnCEIPQFNnk ?
How ?
4 A
What genes to add to #CElegans (nematode worm w 302 backbone neurons) to 100x lifespan, from 3 weeks to 300 weeks re #ExtremeLongevity #AgingReversal & per @geochurch https://youtu.be/
https://x.com/WorldUnivAndSch/
https://x.com/sgkmacleod/
https://x.com/WUaSPress/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
Caenorhabditis elegans
The organism with 302 neurons serving as its backbone is the nematode worm
3 weeks lifespan
https://scott-macleod.
Agenda item 5
Friday, September 19, 2025
Purple Needlegrass (Stipa pulchra): How best can MIT OCW-centric wiki World University and School revolutionize education with machine learning and AI? and How best can #MIT OCW centric Wiki @WorldUnivAndSch - http://
5 A
How best can MIT OCW-centric wiki World University and School revolutionize education with machine learning and AI?
How best can #MIT OCW centric Wiki @WorldUnivAndSch - http://
Gemini -
How WUaS can revolutionize education with AI for enjoyment
World University and School (WUaS) can leverage machine learning and AI to make education intensely enjoyable by transforming the passive act of content consumption into an active, immersive, and personalized experience. This can be done by applying AI principles—such as those articulated by Peter Norvig—to create a system that is not only effective but also highly engaging across all academic levels, from high school to doctoral studies.
1. Making Learning Intensely Enjoyable
The key to making education enjoyable is to make it interactive and personally meaningful. AI can achieve this through:
Gamification and Challenge-Based Learning: AI can turn learning modules into games by introducing quests, badges, leaderboards, and collaborative challenges. A student might be tasked with "solving the quantum computing mystery," where the AI dynamically adjusts the difficulty of the puzzles based on their progress. This makes the learning process feel like an adventure.
Personalized, Immersive Narratives: AI can create a story-driven curriculum. For a history course, the AI could generate an interactive historical narrative where the student is a character making decisions that affect the course of events. In a medical degree (MD) program, the student could interact with a hyper-realistic AI patient, diagnosing and treating their conditions in a simulated environment.
AI-Powered Socratic Tutors: Rather than simply providing answers, AI can act as a Socratic guide, asking thoughtful questions to prompt critical thinking. This makes studying for a PhD or Law degree, which requires deep analysis and argumentation, less about rote memorization and more about an intellectual sparring match, a process that is highly satisfying for learners.
2. Tailoring Enjoyment Across Degree Levels
The approach to making learning enjoyable must be customized for the unique demands of each degree level:
High School (IB) & Associate's (AA/AS): At these foundational levels, the focus can be on micro-learning and bite-sized gamification. Students could learn about biology by playing a game where they build a virtual cell, or grasp math concepts through puzzles that unlock new skills. The AI provides constant, positive reinforcement.
Bachelor's & Master's Degrees: The AI can facilitate collaborative projects with global peers. The enjoyment comes from working with a diverse team on real-world problems. For example, a student in an urban planning course might collaborate with a team from another continent to design a sustainable city, with the AI providing data and feedback.
Law & Medical Degrees (MD): The enjoyment at these professional levels comes from high-stakes simulation. The AI can create complex legal case studies with shifting variables or present simulated medical emergencies that require real-time decision-making. The satisfaction is derived from mastering a difficult challenge and seeing the direct application of their knowledge in a realistic, risk-free environment.
PhD: For doctoral studies, enjoyment is found in discovery and original research. The AI can act as a research assistant, analyzing vast amounts of academic literature, identifying novel connections, and even suggesting new research questions. This frees up the student to focus on the creative, intellectually stimulating parts of their research.
3. Online from Home in All 200 Countries . . .
https://scott-macleod.
5 B
Purple Needlegrass (Stipa pulchra): How best can MIT OCW-centric wiki World University and School revolutionize education with machine learning and AI? and How best can #MIT OCW centric Wiki @WorldUnivAndSch - http://
5 A
How best can MIT OCW-centric wiki World University and School revolutionize education with machine learning and AI?
How best can #MIT OCW centric Wiki @WorldUnivAndSch - http://
Gemini -
How WUaS can revolutionize education with AI for enjoyment
World University and School (WUaS) can leverage machine learning and AI to make education intensely enjoyable by transforming the passive act of content consumption into an active, immersive, and personalized experience. This can be done by applying AI principles—such as those articulated by Peter Norvig—to create a system that is not only effective but also highly engaging across all academic levels, from high school to doctoral studies.
1. Making Learning Intensely Enjoyable
The key to making education enjoyable is to make it interactive and personally meaningful. AI can achieve this through:
Gamification and Challenge-Based Learning: AI can turn learning modules into games by introducing quests, badges, leaderboards, and collaborative challenges. A student might be tasked with "solving the quantum computing mystery," where the AI dynamically adjusts the difficulty of the puzzles based on their progress. This makes the learning process feel like an adventure.
Personalized, Immersive Narratives: AI can create a story-driven curriculum. For a history course, the AI could generate an interactive historical narrative where the student is a character making decisions that affect the course of events. In a medical degree (MD) program, the student could interact with a hyper-realistic AI patient, diagnosing and treating their conditions in a simulated environment.
AI-Powered Socratic Tutors: Rather than simply providing answers, AI can act as a Socratic guide, asking thoughtful questions to prompt critical thinking. This makes studying for a PhD or Law degree, which requires deep analysis and argumentation, less about rote memorization and more about an intellectual sparring match, a process that is highly satisfying for learners.
2. Tailoring Enjoyment Across Degree Levels
The approach to making learning enjoyable must be customized for the unique demands of each degree level:
High School (IB) & Associate's (AA/AS): At these foundational levels, the focus can be on micro-learning and bite-sized gamification. Students could learn about biology by playing a game where they build a virtual cell, or grasp math concepts through puzzles that unlock new skills. The AI provides constant, positive reinforcement.
Bachelor's & Master's Degrees: The AI can facilitate collaborative projects with global peers. The enjoyment comes from working with a diverse team on real-world problems. For example, a student in an urban planning course might collaborate with a team from another continent to design a sustainable city, with the AI providing data and feedback.
Law & Medical Degrees (MD): The enjoyment at these professional levels comes from high-stakes simulation. The AI can create complex legal case studies with shifting variables or present simulated medical emergencies that require real-time decision-making. The satisfaction is derived from mastering a difficult challenge and seeing the direct application of their knowledge in a realistic, risk-free environment.
PhD: For doctoral studies, enjoyment is found in discovery and original research. The AI can act as a research assistant, analyzing vast amounts of academic literature, identifying novel connections, and even suggesting new research questions. This frees up the student to focus on the creative, intellectually stimulating parts of their research.
3. Online from Home in All 200 Countries . . .
https://scott-macleod.
5 B
How best can #MITOCWcentric Wiki @WorldUnivAndSch - http://
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/sgkmacleod/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/scottmacleod/
Gemini: How best can MIT OCW-centric wiki World University and School - http://
https://g.co/gemini/share/
5 C
How best can MIT OCW-centric wiki World University and School - http://
https://g.co/gemini/share/
Based on World University and School's (WUaS) mission and a synthesis of Peter Norvig's work and broader trends in educational AI, here is a strategic plan for how WUaS can use machine learning and AI to achieve its goals of providing free degrees and wiki schools in all 200 countries and 7,159 languages.
The Foundation: Content and Scalability
The core of WUaS is its wiki model, which aims to adapt and build upon MIT OpenCourseWare (OCW) materials. The primary challenge is not just translating content, but adapting it to be culturally and pedagogically relevant to a global audience. AI and machine learning can address this on a massive scale:
Machine Translation and Localization: To make a course available in 7,159 languages
https://scott-macleod.
Agenda item 6
Saturday, September 20, 2025
California poppy (Eschscholzia californica): With this #PhysicalMuseumRoom w #GoogleAI https://youtu.be/
Begin developing a #
With this #PhysicalMuseumRoom w #GoogleAI
https://youtu.be/1XF-NG_35NE w #DemisHassabis #ScottPelley
Develop TWO #WUaSHospitalRoomPrototypes in #Canyon94516shop ONE as #ToyotaAmbulanceVan for #WUaSTeachingHospitals in collab w #KaiserPerm w #GStreetViewRoom https://
https://x.com/WorldUnivAndSch/
https://x.com/Q_YogaMacFlower/
Hassabis image -
https://x.com/HarbinBook/
https://x.com/WUaSPress/
https://x.com/scottmacleod/
https://x.com/sgkmacleod/
https://x.com/TheOpenBand/
*
in 200 countries and in their main languages -
With this #PhysicalMuseumRoom w #GoogleAI
https://youtu.be/1XF-NG_35NE w #DemisHassabis #ScottPelley
Develop TWO #WUaSHospitalRoomPrototypes in #Canyon94516shop in collab w #KaiserPerm w #GStreetViewRoom https://
https://youtu.be/1XF-NG_35NE
https://youtu.be/q9FBhEAXRY4
https://scott-macleod.
Agenda item 7
Add to #TextInTheSidebar this paper
https://www.genomeweb.com/
https://www.genomeweb.com/
Methylation - and its potential relevance for aging reversal and extreme longevity ?
How best w #Epinoma to add to #TextInTheSidebar this paper
https://www.genomeweb.com/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/TheOpenBand/
https://x.com/scottmacleod/
Retweeting -
george church
@geochurch
Epinoma to Commercialize Methylation-Preserving Amplification Chemistry Developed at UChicago
Sep 19, 2025 | Andrew P. Han
https://www.genomeweb.com/
https://x.com/geochurch/
https://scott-macleod.
7 A
AND could this - George Church's Twitter post = be a response to item 3 and 3 B, - regarding adding copies of genes back into the body even to reverse aging?
7 B
How could methylation at the molecular level lead to gene expression to extreme longevity for C Elegans from 3 weeks to 300 weeks of life, so 100 times longer than C Elegans maximum lifespan presently?
A lifespan of 300 weeks for C. elegans is a speculative scenario that dramatically exceeds the current maximum observed lifespan, even with genetic manipulation. Current longevity interventions using methylation pathways achieve impressive, yet far more modest, lifespan extensions. A 100-fold increase would require a complex and synergistic cascade of unprecedented epigenetic changes, rather than a single modification.
If such extreme longevity were possible through methylation, it would likely involve three coordinated molecular processes: a fundamental epigenetic reset, reprogramming of major metabolic pathways, and robust stabilization of the genome.
1. Epigenetic resetting and silencing of aging programs
Aging is associated with "epigenetic drift," the gradual erosion of the epigenome that disrupts gene expression patterns over time. Extreme longevity via methylation would require a mechanism to actively prevent or reverse this degradation, effectively "rebooting" the organism's gene expression to a youthful state.
This would involve:
- Widespread demethylation: Aging is linked to the age-dependent accumulation of the repressive N6-adenine methylation (6mA) mark in transposable elements, leading to their upregulation. To achieve extreme longevity, a hypothetical mechanism would need to prevent this build-up. This could involve hyperactivation of the N6-adenine demethylase, NMAD-1, to maintain youthful methylation patterns and keep transposable elements silenced.
- Targeted histone modification: Methylation can also occur on histones, the proteins around which DNA is wound. For instance, high levels of the activating H3K4me3 mark are linked to active transcription, while the repressive H3K27me3 mark is associated with silenced genes. In worms, deficiencies in the COMPASS complex, which mediates H3K4me3, and reductions of the H3K27me3 demethylase UTX-1 can both extend lifespan, suggesting a delicate balance is key. For extreme longevity, methylation would need to be precisely controlled to silence "pro-aging" genes while keeping "longevity" genes active.
2. Genetic reprogramming of metabolic and cellular maintenance pathways
Extreme lifespan extension would necessitate changes far beyond simply slowing down aging. It would require reprogramming fundamental biological processes through precise epigenetic control of metabolic genes.
This could include:
- Upregulation of stress-response genes: Extreme longevity would need a vastly enhanced cellular defense system. Methylation patterns could be altered to maintain the overexpression of genes regulated by the transcription factors DAF-16 (FOXO) and SKN-1 (Nrf2), which are involved in stress resistance and lifespan extension. For instance, methylation could permanently boost the expression of antioxidants like sod-3, heat-shock proteins, and detoxification enzymes to a level that prevents age-related damage.
- Enhanced autophagy and proteostasis: The natural decline in the cell's ability to clear damaged proteins and organelles would need to be reversed. This could be achieved by methylation driving the persistent upregulation of autophagy genes, potentially controlled by the transcription factor HLH-30 (TFEB), a pathway inhibited by the mTOR pathway.
- Constitutive activation of metabolic pathways: Longevity is linked to nutrient sensing pathways like insulin/IGF-1 signaling (IIS). A dramatic extension of lifespan might involve methylation mimicking a state of permanent dietary restriction by reducing IIS signaling. This could be achieved by hyper-methylating key IIS-promoting genes, leading to the continual activation of the longevity-associated DAF-16 and SKN-1 transcription factors.
3. Genome stabilization and suppression of genomic instability
Aging is associated with increasing genomic instability, as transposable elements (TEs) become more active and the machinery for DNA repair becomes less efficient. A 100-fold increase in lifespan would require a mechanism to maintain genomic integrity indefinitely.
This could involve:
- Permanent TE silencing: A powerful methylation-based system would have to keep TEs silenced throughout the organism's entire lifespan. In normal worms, N6-adenine methylation of TEs increases with age, leading to their transcription. To achieve extreme longevity, this process would need to be suppressed or reprogrammed, potentially by a constitutively active demethylase like NMAD-1.
- Improved DNA repair: The methylation could upregulate DNA repair mechanisms that would otherwise deteriorate with age. This would prevent the gradual accumulation of mutations and maintain the health of the organism's DNA over its extended life.
Why this is a hypothetical scenario
While methylation is a crucial part of lifespan regulation, a 100-fold increase (from 3 weeks to 300 weeks) is beyond the current understanding of biological limits. Factors that make this scenario highly speculative include:
- An "epigenetic ceiling": Combining lifespan-extending interventions in C. elegans has shown that effects can be additive, but they appear to hit an upper limit, such as in daf-2;set double mutants, which reached approximately 100 days.
- Complexity and coordination: Achieving a 100-fold extension would not just require altering one pathway but orchestrating the simultaneous, and likely permanent, modulation of dozens of interconnected pathways. The off-target effects of such massive, long-term epigenetic manipulation are unknown and could be lethal or lead to severe health decline, regardless of lifespan.
- The unknown factors of aging: A 100-fold extension may be impossible because aging involves more complex and poorly understood mechanisms that simply cannot be overcome by altering methylation patterns.
Agenda item 8
Sunday, September 21, 2025
Great egret (Ardea alba): Is Toyota a Shinto or Buddhist company in Japan? * No, but the company's foundational ethics are influenced by #Shintoism, #Buddhism, #Confucianism, #Daoism. Toyota's Way - https://global.toyota/en/
8 A
No, but the company's foundational ethics are influenced by #Shintoism, #Buddhism, #Confucianism, #Daoism. Toyota's Way - https://global.toyota/en/
https://x.com/Q_YogaMacFlower/
https://x.com/HarbinBook/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://x.com/TheOpenBand/
https://lnkd.in/p/gyDnfwyH
https://lnkd.in/p/gGKyHGUR ~
https://lnkd.in/p/gJyGKJfz
Agenda item 99
MIT OCW-centric wiki World University and School's two beginning wings' web pages are working again and still in a single domain URL ...
Again -
MIT OCW-centric wiki World University and School's two beginning wings' web pages are working again after about 3 weeks of being down !
I think WUaS's 2 wings
AND
will also remain together for the foreseeable future in one domain URL. And the downtime was due to our WUaS web host Gate.com VERIFICATION process ... and potentially in communication with the US federal government I postulate. And see - https://scott-macleod.
* * * *
WUaS Corporation
2nd of 2 WUaS wings -
for profit general stock company legal entity in the state of California -
WUaS Corporation - WUaS Press
WUaS Corporation / Academic Press in 7159 languages with machine learning
Agenda item A
Could or how could Chengdiao Fan help the WUaS Corporation multi -list on stock exchanges, such as the Silicon Valley Long-term Stock Exchange, and the NASDAQ + ... and with WUaS's Stanford Mine Pi partnering email ... and in WUaS seeking to code for all 7.9 billion people on the planet from here - https://wiki.
Great: #DrChengdiaoFan, 1 of 2 #PiFounders, to speak @ #TOKEN2049inSingapore-1 of the largest crypto events in the world! W partnering email fr #StanfordMinePi to @WUaSPress /#WUaSCorp how best @WorldUnivAndSch to distrib #PiCrypto https://minepi.com/
https://x.com/WUaSPress/
Agenda item B
Toyota Robotics & Boston Dynamics' Atlas
Appreciating #ToyotaRoboticsBostonDynamics #PhysicalDigitalSim How best to code for #LBMs in #RealisticVirtualEarth #ForSurgery in #
https://x.com/WorldUnivAndSch/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://remma.fr/en/model/
https://scott-macleod.
Appreciating #ToyotaRoboticsBostonDynamics #PhysicalDigitalSim How best to code for #LBMs in #RealisticVirtualEarth #ForSurgery in #
https://x.com/WorldUnivAndSch/
https://x.com/WorldUnivAndSch/
https://x.com/WUaSPress/
https://x.com/HarbinBook/
https://x.com/TheOpenBand/
https://x.com/Q_YogaMacFlower/
https://x.com/sgkmacleod/
https://x.com/scottmacleod/
https://remma.fr/en/model/
https://scott-macleod.
Agenda item C
Lego Spike Prime Robotics' kits - for check out or in library use? - in the Contra Costa libraries? Learn AI and Machine Learning with Lego Robotics and Scratch programming language - for kids and adults?
Amy, (Contra Costa public library system),
Thanks, and I just got back pretty recently in the SF East Bay after 3 weeks away.
Waiting a bit to look at this form again - https://ccclib.org/program-
Can kids learn the basics of coding for #AIandMLWUaS & #LLMs with #ScratchProgrammingLanguage & playing w eg #LegoSpikePrimeRoboticsKit?
#GeminiAIreLearningAIandML
#GeminiAIreLegoAndScratch
https://g.co/gemini/share/
https://youtube.com/shorts/
https://wiki.
https://x.com/WorldUnivAndSch/
AND
Machine Learning for Kids
Teach a computer to play a game
https://
Teachable Machine
Train a computer to recognize your own images, sounds, & poses.
https://teachablemachine.
https://
... and until I can get my Lego Spike Prime robotics' kit out of storage and explore these a little further myself ... (and I would be doing this as an individual, but potentially letting people know about free online MIT OCW-centric World Univ & Sch degrees from home, and after WUaS becomes accredited further).
Might the Contra Costa library system be interested eventually in getting some Lego Spike Prime robotics' kits and for library patrons - from WUaS Educational Services stores? (The WUaS Press / WUaS Educational Services' Store is actually an authorized reseller of 3 Lego Robotics' kits - http://
Thanks,
Scott
https://
https://scott-macleod.
Amy, (Contra Costa public library system),
Thanks, and I just got back pretty recently in the SF East Bay after 3 weeks away.
Waiting a bit to look at this form again - https://ccclib.org/program-
Can kids learn the basics of coding for #AIandMLWUaS & #LLMs with #ScratchProgrammingLanguage & playing w eg #LegoSpikePrimeRoboticsKit?
#GeminiAIreLearningAIandML
#GeminiAIreLegoAndScratch
https://g.co/gemini/share/
https://youtube.com/shorts/
https://wiki.
https://x.com/WorldUnivAndSch/
AND
Machine Learning for Kids
Teach a computer to play a game
https://
Teachable Machine
Train a computer to recognize your own images, sounds, & poses.
https://teachablemachine.
https://
... and until I can get my Lego Spike Prime robotics' kit out of storage and explore these a little further myself ... (and I would be doing this as an individual, but potentially letting people know about free online MIT OCW-centric World Univ & Sch degrees from home, and after WUaS becomes accredited further).
Might the Contra Costa library system be interested eventually in getting some Lego Spike Prime robotics' kits and for library patrons - from WUaS Educational Services stores? (The WUaS Press / WUaS Educational Services' Store is actually an authorized reseller of 3 Lego Robotics' kits - http://
Thanks,
Scott
https://
https://scott-macleod.
C a
Scott,
At this time I don't think the library is interested in purchasing any Lego Spike Prime robotics' kits as circulating countywide items. I can't speak for the Friends of the Library groups at any individual locations or to the interest of a library in hosting a program. Please go ahead and fill out the program proposal and then individual branches can reach out to you for more information.
Thank you,
Amy Mockoski (she/her) Librarian III- Youth Services Contra Costa County Library 777 Arnold Drive, Suite 210, Martinez, CA 94553 Email: amy.mockoski@library. Web: www.ccclib.org
|
From: Scott MacLeod <sgkmacleod@
Sent: Friday, September 19, 2025 11:50 AM
Sent: Friday, September 19, 2025 11:50 AM
C b
Dear Amy, & Byron (who has lived in Moraga since the late 1990s),
Great to hear from you. Thanks for your email just now. I explore setting up a Lego Spike Prime Robotics' club in libraries further in today's M 9/22/25 WUaS News and Q&A in Agenda Item C on the WUaS Corp / the WUaS Educational Services' Store / WUaS Academic Press in 7159 known living languages' wing, which video recording I'll post soon here - https://
Let me talk with my friend from Reed College in Portland Oregon, from 1979, Byron Hann MD PhD, who has lived in Moraga since around 1998 ... and regarding his knowledge of possibly Moraga or Contra Costa Library systems' Friends of the Library people, or how even to explore C county in one way or another (perhaps via the CC Friends of teh Library) getting possibly Lego Spike Prime robotics' kits from WUaS itself, if I start this Lego Robotics with Scratch programming club ... Brainstorming, Could MIT OCW-centric wiki World Univ & Sch WUaS get the WUaS Educational Services' Stores for robotics, books, computers, hospital technologies / Academic Press at WUaS OPERATIONAL ... and with PUBLIC libraries' SYSTEMS in all 58 counties in the state of California (and please see the PS, PPS and PPPS) - AND regarding the free online MIT OCW-centric WUaS degrees from home that WUaS will offer as WUaS accredits?
Thanks so much,
Scott
Scott GK MacLeod
Will post the video here soon -
and here -
PS
Searched on
What library systems in California counties have lego spike prime robotics kits ?
Multiple California library systems provide Lego Spike Prime robotics kits, often through in-library events rather than as take-home items. Availability can also vary by branch. Contacting your local library branch is the best way to confirm their specific offerings.
Library systems offering Lego Spike Prime kits
- Redwood City Public Library (San Mateo County): The library system's Schaberg Branch offers free, multi-week LEGO Spike Prime robotics sessions.
- Santa Cruz Public Libraries (Santa Cruz County): The Boulder Creek branch hosts multi-part series that use LEGO Spike Prime kits to teach engineering and programming skills.
- Sacramento Public Library (Sacramento County): The Orangevale branch has hosted events that allow kids to design, build, and program robots using the kits.
- San José Public Library (Santa Clara County): Several events using Lego Spike robotics have been held at various branches within this system.
- Riverside County Library System (Riverside County): Some branches, like the one in El Cerrito, have offered Lego Robotics events featuring Spike Prime kits.
Contra Costa County Library
The Contra Costa County Library does not explicitly list Lego Spike Prime kits as a lendable item. However, the system does offer other robotics and maker resources. Some programs include:
- Raspberry Pi Kits: These are available for checkout and teach coding.
- Other STEAM Kits: The library provides "grab-and-go" kits for building, coding, and nature exploration.
- Lego Clubs: Events like the "Lego Club" are held at various branches and provide standard Lego blocks for building.
To see if Lego Spike Prime kits have been added, or to learn about the current availability of robotics programs, you should contact the Contra Costa County Library directly
PPS
Further -
While WUaS is an AUTHORIZED reseller of 3 Lego Robotics' kits including Lego Spike Prime Robotics' kits - http://
PPPS
Could there be an opportunity here for Contra Costa county library patrons to play with Lego Spike Prime robotics' kits and with the Scratch programming language, and for kids and adults to learn the basics of AI and ML ... and hands on by playing?
Am seeking at WUaS to explore this further ...
Best regards,
Scott
--
--
Society, Information Technology, and the Global University (2025, forthcoming)
Scottish Small Piping album #2 - Honey Piobaireachd (2022)
- https://twitter.com/
Scottish Small Piping album #1 Honey in the Bag ~ Out of the Air tune (2020)
Order Book #4 To the Dance or the Pools? ~ Virtually! How different it is to soak at Harbin Hot Springs, than to realize it in virtual reality (2019)
Order Book #3 Winding Road Rainbow: Harbin, Wandering & the Poetry of Loving Bliss (2018)
Order Book #2 Haiku-ish and Other Loving Hippie Harbin Poetry (2017)
Order Actual-Virtual Ethnographic Book #1: Naked Harbin Ethnography (2016)
- Scott GK MacLeod
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki,
World University & School (WUaS)
- USPS US Post Office, General Delivery, Canyon, CA 94516
1) non-profit 501(c)(3) Public Charity
MIT OCW-centric,
World University and School - http://
2) for profit general stock company WUaS Corporation in CA - http://
(o) 415 480 4577 - sgkmacleod@
(m) 412 478 0116 - sgkmacleod@gmail.com
World Univ & Sch Innovation Research -
*
.jpg/1599px-Red-tailed_Hawk_(45812546121).jpg)
_in_flight.jpg?20110325035341)
https://en.wikipedia.org/wiki/Red-tailed_hawk
https://commons.wikimedia.org/wiki/Category:Buteo_jamaicensis
https://commons.wikimedia.org/wiki/Category:Buteo_jamaicensis_borealis
...
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