Saturday, September 20, 2025

California poppy (Eschscholzia californica): With this #PhysicalMuseumRoom w #GoogleAI https://youtu.be/1XF-NG_35NE w #DemisHassabis #ScottPelley Develop TWO #WUaSHospitalRoomPrototypes in #Canyon94516shop ONE as #ToyotaAmbulanceVan for #WUaSTeachingHospitals in collab w #KaiserPerm w #GStreetViewRoom https://youtu.be/q9FBhEAXRY4 ~ * * * Methylation - and its potential relevance for aging reversal and extreme longevity How best w #Epinoma to add to #TextInTheSidebar this paper https://www.genomeweb.com/sample-preparation/epinoma-commercialize-methylation-preserving-amplification-chemistry-developed to a #RealisticVirtualEarthForMethylation #ForMethylationInfoTech & GENERATE #MolecularModelsIT in #GStreetView w #GTimeSlider #GMoleculeView #TensorFlowAI for #AgingReversal & #ExtremeLongevity ~

 



Begin developing a #RealisticvirtualEarthForAgingReversal in #Canyon94516shop in collab w #KaiserPermanente in #GStreetViewRoom 


With this #PhysicalMuseumRoom w #GoogleAI
https://youtu.be/1XF-NG_35NE w #DemisHassabis #ScottPelley
Develop TWO #WUaSHospitalRoomPrototypes in #Canyon94516shop ONE as #ToyotaAmbulanceVan for #WUaSTeachingHospitals in collab w #KaiserPerm w #GStreetViewRoom https://youtu.be/q9FBhEAXRY4 ~

https://x.com/WorldUnivAndSch/status/1969601107312984186

https://x.com/Q_YogaMacFlower/status/1969601212262859196


Hassabis image - 









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in 200 countries and in their main languages -  

With this #PhysicalMuseumRoom w #GoogleAI
https://youtu.be/1XF-NG_35NE w #DemisHassabis #ScottPelley
Develop TWO #WUaSHospitalRoomPrototypes in #Canyon94516shop in collab w #KaiserPerm w #GStreetViewRoom https://youtu.be/q9FBhEAXRY4 ONE  as #ToyotaAmbulanceVan for #WUaSTeachingHospitals in 200 countries ~









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Begin developing a #RealisticvirtualEarthForAgingReversal in #Canyon94516shop in collaboration with #KaiserPermanente in #GStreetViewRoom ...?

Begin developing a #RealisticvirtualEarthForAgingReversal in #Canyon94516shop in collab w #KaiserPermanente in #GStreetViewRoom https://youtu.be/q9FBhEAXRY4 & as #WUaSHospitalRoomPrototype, AND re Room https://youtu.be/1XF-NG_35NE #DemisHassabis #ScottPelley 1st for 1 #GeneticDrugTherapy?

https://x.com/WorldUnivAndSch/status/1960756291711991877

https://x.com/TheOpenBand/status/1960757685537923111

https://x.com/Q_YogaMacFlower/status/1960756668851216616

https://x.com/scottmacleod/status/1960756786300117404

https://x.com/HarbinBook/status/1960758127143608608

https://x.com/WUaSPress/status/1960757113678127511

https://x.com/sgkmacleod/status/1960756971554136456


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How to view Google Street View in a smart meeting room.

Igloo Vision

https://youtu.be/q9FBhEAXRY4


What's next for AI at DeepMind, Google's artificial intelligence lab | 60 Minutes

https://youtu.be/1XF-NG_35NE

demis hassabis scott pelley 60 minutes


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begin developing a realistic virtual earth for aging reversal in the Canyon 94516 shop at 670 Ridgecrest Rd on M Sep 1, 2025, would we begin with getting - in collaboration with Kaiser Permanente - smart screen panels for 5 sides of a room and a console like this
"How to view Google Street View in a smart meeting room." (Feb 23, 2022)
Igloo Vision:
https://youtu.be/q9FBhEAXRY4
... and to create a WUaS Hospital Room prototype, with a focus too on developing Pegman in Street View, as Avatar Agent Electronic Health Records at the street view, cell view and molecule view levels and AI libraries of these too,
and by first putting in some walls like at the 2:10 minute marker here into the shop -
"What's next for AI at DeepMind, Google's artificial intelligence lab | 60 Minutes"  (Apr 20, 2025)
https://youtu.be/1XF-NG_35NE
(Demis Hassabis Scott Pelley 60 Minutes)
... and would you also come into conversation in all of this with MIT, Harvard, Stanford, UCSF coders + as this room develops ... I think a Realistic Virtual Earth for Aging Reversal in a WUaS Hospital room prototype could garner the involvement of some of the greatest computer scientists and aging reversal medical doctor specialists in the world? (And all beginning Monday 9/1/25 with US federal and state of California law working effectively together in new ways).
Hugs, Scott

And could we develop this WUaS Academic Medical Center Realistic Virtual Earth for Aging Reversal further for a single genetic drug therapy or vaccine end product initially as well?



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Dear Byron & Cindy (Hann MDs), Ed (Smyth MD, Kaiser Permanente NorCal), Drs., Pin/Sid (Mazumdar HHS), Peter (Norvig, Google AI), George (Church, Harvard Med Sch), US Senator Alex Padilla from CA,  (John Tadler, Allegheny County Police Lt. in Pgh, and re FBI workshop in 2013), US Senator from MA and former Harvard Law Professor Elizabeth Warren, Friends/Quakers, UUs, Yogis, scientists, ecologists & evolutionary biologists, All, 

How are you? Great to see you, Byron, when I returned from Massachusetts recently. If we could begin developing a realistic virtual earth for aging reversal in the Canyon 94516 shop at 670 Ridgecrest Rd on M Sep 1, 2025, would we begin with getting - in collaboration with Kaiser Permanente - smart screen panels for 5 sides of a room and a console like this
"How to view Google Street View in a smart meeting room." (Feb 23, 2022)
Igloo Vision:
https://youtu.be/q9FBhEAXRY4
... and to create a WUaS Hospital Room prototype, with a focus too on developing Pegman in Street View, as Avatar Agent Electronic Health Records at the street view, cell view and molecule view levels and AI libraries of these too,
and by first putting in some walls like at the 2:10 minute marker here into the shop -
"What's next for AI at DeepMind, Google's artificial intelligence lab | 60 Minutes"  (Apr 20, 2025)
https://youtu.be/1XF-NG_35NE
(Demis Hassabis Scott Pelley 60 Minutes)
... and would you also come into conversation in all of this with MIT, Harvard, Stanford, UCSF coders + as this room develops ... I think a Realistic Virtual Earth for Aging Reversal in a WUaS Hospital room prototype could garner the involvement of some of the greatest computer scientists and aging reversal medical doctor specialists in the world? (And all beginning Monday 9/1/25 with US federal and state of California law working effectively together in new ways).
Hugs, Scott

And could we develop this WUaS Academic Medical Center Realistic Virtual Earth for Aging Reversal further for a single genetic drug therapy or vaccine end product initially as well?

Best regards, abolitionally, kindly,

Scott

Wednesday, August 13, 2025
American Holly (Ilex opaca): "Society, Information Technology, and the Global University" upcoming book @WUaSPress, Pt 2 * * * Cuttyhunk public library today - Tuesday August 12, 2025 * * * Re: Developments in Canyon 94516 (continuing - Greetings from Cuttyhunk island, Massachusetts. And thanks Ed and John for precipitating my and the MIT OCW-centric wiki World University and School's 200 virtual online WUaS Medical Schools and the WUaS Academic Medical Center moving forward ...) 







* * * 



Methylation - and its potential relevance for aging reversal and extreme longevity


How best w #Epinoma to add to #TextInTheSidebar this paper
https://www.genomeweb.com/sample-preparation/epinoma-commercialize-methylation-preserving-amplification-chemistry-developed to a #RealisticVirtualEarthForMethylation #ForMethylationInfoTech & GENERATE #MolecularModelsIT in #GStreetView w #GTimeSlider #GMoleculeView #TensorFlowAI for #AgingReversal & #ExtremeLongevity ~








Retweeting -

george church
@geochurch

Epinoma to Commercialize Methylation-Preserving Amplification Chemistry Developed at UChicago
Sep 19, 2025 | Andrew P. Han






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Methylation is the addition of a methyl group (CH3) to another molecule - to DNA, RNA, proteins, lipids, and other molecules



Photographs of a standalone methyl group (image.gif
) are not possible because it is a highly reactive intermediate that exists for only a fraction of a second. However, molecular models, chemical diagrams, and molecular videography of methylation events are available. 


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photos of methyl molecule ch3 molecular videography of methylation

Methylation



george church
@geochurch

Epinoma to Commercialize Methylation-Preserving Amplification Chemistry Developed at UChicago
Sep 19, 2025 | Andrew P. Han

https://www.genomeweb.com/sample-preparation/epinoma-commercialize-methylation-preserving-amplification-chemistry-developed

https://x.com/geochurch/status/1969134045524013290




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Genome-wide single-molecule analysis of DNA methylation reveals heterogeneous patterns

Oxford Nanopore Technologies

https://youtu.be/zCjLY2dWxBg



CH3 - (Methyl anion) Molecular Geometry, Bond Angles

https://youtu.be/eT4mkIsc6bM 


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Photographs of a standalone methyl group (
image.gif
) are not possible because it is a highly reactive intermediate that exists for only a fraction of a second. However, molecular models, chemical diagrams, and molecular videography of methylation events are available. 
Photos of the methyl group (
image.gif
) 
Since a methyl radical (
image.gif
), cation (
image.gif
), or anion (
image.gif
) cannot be photographed directly, images depict its molecular structure using artistic renderings, 3D models, and chemical diagrams. 
  • Stock images: Websites like Shutterstock and Alamy offer stock images with illustrations and 3D renderings of the methyl group.
  • Vector illustrations: These images show the methyl group's structural formula (
    image.gif
    ) and its position as an alkyl functional group within larger organic compounds.
  • Molecular model variations: Videos and images illustrate the geometry of the methyl group depending on whether it is a radical (trigonal planar), a cation (trigonal planar), or an anion (trigonal pyramidal). 
Molecular videography of methylation 
Molecular videography of methylation does not typically exist as a traditional video recording, as the event occurs on an atomic scale. Instead, the process is demonstrated using animations and simulations that show a methyl group attaching to a molecule. These videos often focus on biological processes such as DNA methylation. 
  • Epigenetics and DNA methylation: Educational videos from sources like NutraNourish and YouTube show how a methyl group is added to a DNA molecule to regulate gene expression. The videos use molecular models to illustrate the biological impact of this chemical modification.
  • Nanopore sequencing animations: Videos from sources like Nanopore Technologies demonstrate how single-molecule analysis techniques can reveal heterogeneous patterns of DNA methylation across the genome.
  • Lecture and tutorial animations: Channels such as MadMedicine and Study.com feature animated explanations that break down the methylation process for educational purposes, covering topics like DNA methylation and organic chemistry



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Methylation is the biological process of adding a methyl group (a small molecule) to other molecules, including DNA and proteins, and it's crucial for regulating gene expression by turning genes "on" or "off". This process, which is an epigenetic mechanism, influences cellular functions, and alterations in methylation patterns are associated with various health conditions, from heart disease and cancer to autoimmune disorders and aging. Diet, lifestyle, and aging can impact methylation levels, with factors like folic acid and vitamin B12 intake affecting the process. 
What is methylation?
  • Chemical Process: Methylation is the addition of a methyl group (CH3) to another molecule, a fundamental biochemical process across biology and chemistry.
  • Molecular Targets: Methyl groups are added to DNA, RNA, proteins, lipids, and other molecules.
How does it work in the body?
  • Gene Regulation: DNA methylation can change the activity of a gene without altering its DNA sequence. When a methyl group attaches to a DNA segment in a gene's promoter, it typically "silences" or turns the gene "off," preventing protein production.
  • Epigenetics: Methylation is a key component of epigenetics, a system of gene regulation that controls gene activity and expression.
  • Imprinting: This process regulates gene expression that differs between maternal and paternal genomes.
  • Cell Division: Methylation patterns can be maintained as cells divide, helping to pass on genetic information and regulate cell differentiation. 
Why is it important?
  • Health & Disease: Aberrant methylation patterns have been linked to diseases such as cancer, heart disease, anxiety, and autoimmune conditions. 
  • Aging: DNA methylation levels change with age, and these changes can be used as an "epigenetic clock" to estimate biological age. 
  • Development: Methylation is vital for normal development and for regulating cell differentiation in various tissues. 
What influences methylation?
  • Diet: Nutrients like folic acid, vitamin B12, and vitamin B6 act as methyl donors, providing the methyl groups needed for methylation. 
  • Lifestyle: Exercise and avoiding toxins can positively influence methylation, while poor lifestyle choices can negatively impact it. 
  • Environment: Exposure to environmental factors can affect methylation patterns.


--

Society, Information Technology, and the Global University (2025, forthcoming) 

- Scott GK MacLeod  
Founder, President, CEO & Professor
CC-4 licensed MIT OCW-centric, Wiki, 
World University & School (WUaS) 
- USPS US Post Office, General Delivery, Canyon, CA 94516 


1) non-profit 501(c)(3) Public Charity 
MIT OCW-centric, 

2) for profit general stock company WUaS Corporation in CA - http://worlduniversityandschool.org/AcademicPress.html

(m) 412 478 0116 - sgkmacleod@gmail.com 


World Univ & Sch Innovation Research - 







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https://upload.wikimedia.org/wikipedia/commons/thumb/8/8e/California_Poppies_%2826444987332%29.jpg/1532px-California_Poppies_%2826444987332%29.jpg?20160730225659























https://www.mostlynatives.com/sites/default/files/styles/main_plant_photo_breakpoints_theme_mostly_natives_wide_1x/public/eschscholziacmaritima1.jpg?itok=U6LyvDNQ&timestamp=1412750101












https://en.wikipedia.org/wiki/Eschscholzia_californica

https://simple.wikipedia.org/wiki/Eschscholzia_californica

https://commons.wikimedia.org/wiki/Category:Eschscholzia_californica


https://calscape.org/Eschscholzia-californica-ssp.-maritima-'Coastal-Form'-(Coastal-California-Poppy)


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